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Akademický článek

Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y 4 Receptor Positive Allosteric Modulator VU0506013.

Autor: Schüß C; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany., Vu O; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States., Mishra NM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Tough IR; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London SE1 1UL, U.K., Du Y; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States., Stichel J; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany., Cox HM; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London SE1 1UL, U.K., Weaver CD; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States., Meiler J; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Institute for Drug Discovery, Leipzig University, Leipzig 04103, Germany., Emmitte KA; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Beck-Sickinger AG; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Jul 13; Vol. 66 (13), pp. 8745-8766. Date of Electronic Publication: 2023 Jun 20.

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Akademický článek

Structure-activity relationship studies in a new series of 2-amino-N-phenylacetamide inhibitors of Slack potassium channels.

Autor: Qunies AM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA; Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, USA., Mishra NM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA., Spitznagel BD; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA., Du Y; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA., Acuña VS; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA., David Weaver C; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA., Emmitte KA; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, USA. Electronic address: kyle.emmitte@unthsc.edu.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Nov 15; Vol. 76, pp. 129013. Date of Electronic Publication: 2022 Sep 29.

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Akademický článek

Large intraspinal cement leak during multilevel cement-augmented screw fixation.

Autor: Jain M; Orthopaedics, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India montu_jn@yahoo.com., Nayak M; Orthopaedics, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India., Sahoo A; Orthopaedics, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India., Mishra NM; Anaesthesia, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India.

Publikováno v: BMJ case reports [BMJ Case Rep] 2021 Dec 23; Vol. 14 (12). Date of Electronic Publication: 2021 Dec 23.

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Akademický článek

Highly Selective Y 4 Receptor Antagonist Binds in an Allosteric Binding Pocket.

Autor: Schüß C; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany., Vu O; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States., Schubert M; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany., Du Y; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States., Mishra NM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Tough IR; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London SE1 1UL, U.K., Stichel J; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany., Weaver CD; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States., Emmitte KA; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Cox HM; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London SE1 1UL, U.K., Meiler J; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Institute for Drug Discovery, Leipzig University, Leipzig 04103, Germany., Beck-Sickinger AG; Institute of Biochemistry, Leipzig University, Leipzig 04103, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Mar 11; Vol. 64 (5), pp. 2801-2814. Date of Electronic Publication: 2021 Feb 17.

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Akademický článek

VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons.

Autor: Spitznagel BD; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States., Mishra NM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Qunies AM; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States.; Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Prael FJ 3rd; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37240, United States., Du Y; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37240, United States., Kozek KA; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37240, United States.; Vanderbilt Medical Scientist Training Program, Vanderbilt University, Nashville, Tennessee 37232, United States., Lazarenko RM; Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee 37212, United States., Denton JS; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee 37212, United States., Emmitte KA; Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas 76107, United States., Weaver CD; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37240, United States.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2020 Nov 04; Vol. 11 (21), pp. 3658-3671. Date of Electronic Publication: 2020 Oct 14.

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