Výsledky vyhledávání - "Mishel Davis"

Molecular Consequences of Silencing Mutant K-ras in Pancreatic Cancer Cells: Justification for K-ras–Directed Therapy

Autor: Rolf A. Brekken, Shane E. Holloway, Guo Liang Shen, Mishel Davis, Jason B. Fleming

Publikováno v: Molecular Cancer Research. 3:413-423

Mutation of the K-ras gene is an early event in the development of pancreatic adenocarcinoma and, therefore, RNA interference (RNAi) directed toward mutant K-ras could represent a novel therapy. In this study, we examine the phenotypic and molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122bc80ef8a3db961e2bce0a3a7632a3
https://doi.org/10.1158/1541-7786.mcr-04-0206

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A Clinically Relevant Model of Human Pancreatic Adenocarcinoma Identifies Patterns of Metastasis Associated with Alterations of the TGF-β/Smad4 Signaling Pathway

Autor: Shane E. Holloway, Jason B. Fleming, Mishel Davis, Raffat Jaber

Publikováno v: International Journal of Gastrointestinal Cancer. 33:61-70

Genetic alterations impacting the TGF-β/Smad4 pathway are found in nearly all pancreatic adenocarcinomas, and recent reports have identified a relationship between DPC4/Smad4 expression and patient survival. In this study we use a clinically relevan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fc641c1fffc1d9ce45b147d6d54afa
https://doi.org/10.1385/ijgc:33:1:61

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TEXT prose and poetry October 2013

Autor: Brigita Orel, Grace Dwyer, Mishel Davis, Sue Woolfe, Simon Holloway

Publikováno v: TEXT. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe61b62fafbb35266a9ba008afc6a354
https://doi.org/10.52086/001c.27574

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Complement Proteins Are Present in Developing Endochondral Bone and May Mediate Cartilage Cell Death and Vascularization

Autor: Marcel E. Nimni, Reuben Eisenstein, José A. Andrades, José Becerra, Mishel Davis, Nino Sorgente

Publikováno v: Experimental Cell Research. 227:208-213

Normal endochondral bone formation follows a temporal sequence: immature or resting chondrocytes move away from the resting zone, proliferate, flatten, become arranged into columns, and finally become hypertrophic, disintegrate, and are replaced by b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae5e9beb0d4803ae96e0409122b6492
https://doi.org/10.1006/excr.1996.0269

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Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion

Autor: Matthew D. Silverman, Peter I. Lelkes, Gladys Lopez, Ramagopal J. Tumuluri, Mishel Davis, James T. Rosenbaum

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 22(4)

Elevated plasma homocysteine is an independent risk factor for atherosclerosis. We hypothesized that homocysteine enhances monocyte/human aortic endothelial cell (HAEC) interactions, a pivotal early event in atherogenesis, by upregulating endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66686ffd09e9ecd7c28526236198e8e
https://pubmed.ncbi.nlm.nih.gov/11950695

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