Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Misha V. Golynskiy"'
Publikováno v:
ChemBioChem. 14:1553-1563
Proper protein folding is a prerequisite for protein stability and enzymatic activity. Although directed evolution can be a powerful tool to investigate enzymatic function and to isolate novel activities, well-designed libraries of folded proteins ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09ba9eb00917401bfb966e6d0f44af6
https://doi.org/10.1002/cbic.201300326
https://doi.org/10.1002/cbic.201300326
Autor:
Stan F.J. van de Graaf, Leo W. J. Klomp, Saskia W.C. van Mil, Maarten Merkx, Ingrid T. G. W. Bijsmans, Misha V. Golynskiy, Lieke M. van der Velden
Publikováno v:
Hepatology, 75(2), 740-752. Wiley
Hepatology (Baltimore, Md.), 57(2), 740-752. John Wiley and Sons Ltd
Hepatology (Baltimore, Md.), 57(2), 740-752. John Wiley and Sons Ltd
Bile acids are pivotal for the absorption of dietary lipids and vitamins and function as important signaling molecules in metabolism. Here, we describe a genetically encoded fluorescent bile acid sensor (BAS) that allows for spatiotemporal monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05988a6272b9b5417d6fb30ccb6a1a8
https://doi.org/10.1002/hep.26012
https://doi.org/10.1002/hep.26012
Publikováno v:
ChemBioChem, 11(16), 2264-2267. Wiley-VCH Verlag
No wash, just go: Classical antibody-detection methods rely on heterogeneous detection schemes that involve multiple, time-consuming binding and washing steps. Here we present a new concept to translate the antigen–antibody interaction directly int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7870de1ba6999326cd85f4fb5a51235
https://research.tue.nl/en/publications/00fe0e91-0aa4-4fd2-bad8-7f7fee8650dd
https://research.tue.nl/en/publications/00fe0e91-0aa4-4fd2-bad8-7f7fee8650dd
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 12:699-709
The manganese transport regulator (MntR) of Bacillus subtilis is a metalloregulatory protein responsible for regulation of genes involved in manganese uptake by this organism. MntR belongs to the iron-responsive DtxR family, but is allosterically reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7213e12e6094325d3117460d701d184
https://doi.org/10.1007/s00775-007-0216-z
https://doi.org/10.1007/s00775-007-0216-z
Publikováno v:
Biochemistry. 44:3380-3389
MntR is a metalloregulatory protein that helps to modulate the level of manganese in Bacillus subtilis. MntR shows a metal-response profile distinct from other members of the DtxR family of metalloregulatory proteins, which are generally considered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7b7666ff443df0e0ede53945451ca9
https://doi.org/10.1021/bi0480741
https://doi.org/10.1021/bi0480741
Publikováno v:
Journal of Organometallic Chemistry. 690:534-538
The synthesis and characterization of two Group VI pentacarbonyl complexes (pfepp)M(CO) 5 (M = Cr 1 , Mo 2 ; pfepp = PPh 2 C 2 F 5 ) are reported. Thermolysis of M(CO) 6 and pfepp in refluxing octane afforded 1 and 2 in moderate yields. These complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23afe79415c67b0755aa99083f0f6db6
https://doi.org/10.1016/j.jorganchem.2004.09.034
https://doi.org/10.1016/j.jorganchem.2004.09.034
Publikováno v:
Methods in Molecular Biology ISBN: 9781627032926
In the past decade, in vitro evolution techniques have been used to improve the performance or alter the activity of a number of different enzymes and have generated enzymes de novo. In this review, we provide an overview of the available in vitro me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14351792d203b996c603a6c476dbc2f4
https://europepmc.org/articles/PMC6924924/
https://europepmc.org/articles/PMC6924924/
Autor:
William E. Draper, Wendy A. Breyer, Rebecca K. Phillips, Kate E. Stoll, Seth M. Cohen, Richard G. Brennan, Howard F. Jenkinson, Joseph I. Kliegman, Hattie K. Brown, Rhoda A. T. Brew-Appiah, Nicholas S. Jakubovics, Misha V. Golynskiy, Arthur Glasfeld
Manganese is an essential nutrient for many pathogenic bacteria and has been linked to virulence in a number of species (1–3). A cofactor for a variety of enzymes involved in fighting oxidative stress, manganese is taken up in bacteria by NRAMP and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a54112d01e25140cdbe59cc9a19d6b
https://europepmc.org/articles/PMC3586275/
https://europepmc.org/articles/PMC3586275/
Manganese transport regulator (MntR) is a member of the diphtheria toxin repressor (DtxR) family of transcription factors that is responsible for manganese homeostasis in Bacillus subtilis. Prior biophysical studies have focused on the metal-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61aeeb9c8a4c612bd0e8b6534664b9d8
https://europepmc.org/articles/PMC2561245/
https://europepmc.org/articles/PMC2561245/
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 58:m70-m71
In the title complex, [Cr(C14H10F5P)2(CO)4], a slightly distorted octahedral geometry is present about the Cr atom which sits at a center of inversion, while the groups about the P atom are in a slightly distorted tetrahedral arrangement. The Cr—P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9d0f3241863bf40e05b5056a53e073c
https://doi.org/10.1107/s1600536802001356
https://doi.org/10.1107/s1600536802001356