Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mischa G. Vrouwe"'
Autor:
Alex Pines, Madelon Dijk, Matthew Makowski, Elisabeth M. Meulenbroek, Mischa G. Vrouwe, Yana van der Weegen, Marijke Baltissen, Pim J. French, Martin E. van Royen, Martijn S. Luijsterburg, Leon H. Mullenders, Michiel Vermeulen, Wim Vermeulen, Navraj S. Pannu, Haico van Attikum
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
An integrated network of chaperones and protein degradation machineries called the proteostasis network (PN) is required to maintain protein homeostasis. Here the authors show that one of the components of the PN, the chaperonin TRiC, interacts with
Externí odkaz:
https://doaj.org/article/349d895dc8574c5db3919c1594d1d33a
Autor:
Leon H.F. Mullenders, Pim J. French, Haico van Attikum, Madelon Dijk, Martijn S. Luijsterburg, Navraj S. Pannu, Mischa G. Vrouwe, Martin E. van Royen, Wim Vermeulen, Elisabeth M. Meulenbroek, Michiel Vermeulen, Matthew M. Makowski, Alex Pines, Yana van der Weegen, Marijke P. Baltissen
Publikováno v:
Nature Communications, 9
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, 9, pp. 1-14
Nature Communications, 9:1040. Nature Publishing Group
Nature Communications, 9, 1-14
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, 9, pp. 1-14
Nature Communications, 9:1040. Nature Publishing Group
Nature Communications, 9, 1-14
Transcription-blocking DNA lesions are removed by transcription-coupled nucleotide excision repair (TC-NER) to preserve cell viability. TC-NER is triggered by the stalling of RNA polymerase II at DNA lesions, leading to the recruitment of TC-NER-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95a3006f2bd3708c2945b52996de77a
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847541/pdf/41467_2018_Article_3484.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847541/pdf/41467_2018_Article_3484.pdf
Publikováno v:
DNA Repair, 10(7), 743-750
A network of DNA damage surveillance systems is triggered by sensing of DNA lesions and the initiation of a signal transduction cascade that activates genome-protection pathways including nucleotide excision repair (NER). NER operates through coordin
Publikováno v:
Journal of Cell Science, 124(3), 435-446
Activation of signaling pathways by UV radiation is a key event in the DNA damage response and initiated by different cellular processes. Here we show that non-cycling cells proficient in nucleotide excision repair (NER) initiate a rapid but transien
Autor:
Nicolas H. Thomä, Kaoru Sugasawa, Paul J. Hensbergen, Syota Matsumoto, Anton J.L. de Groot, Leon H.F. Mullenders, Alex Pines, Jurgen A. Marteijn, André M. Deelder, Martijn S. Luijsterburg, Medine Cansoy, Harry Vrieling, Wim Vermeulen, Dimitris Typas, Mischa G. Vrouwe
Publikováno v:
Journal of Cell Biology, 199(2), 235-249. Rockefeller University Press
The Journal of Cell Biology
The Journal of Cell Biology
PARP1-mediated poly(ADP-ribosyl)ation of DDB2 prolongs its occupation on UV-damaged chromatin and promotes the recruitment of the chromatin remodeler ALC1.
The WD40-repeat protein DDB2 is essential for efficient recognition and subsequent remova
The WD40-repeat protein DDB2 is essential for efficient recognition and subsequent remova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a4773e8c2c7efe468d12e9439a4bd2
https://hdl.handle.net/1887/98481
https://hdl.handle.net/1887/98481
Autor:
Louise von Stechow, Anton J.L. de Groot, Harry Vrieling, Bob van de Water, Branislav Misovic, Jordi Carreras Puigvert, Dimitris Typas, Christian D. Kelstrup, Erik H.J. Danen, Mischa G. Vrouwe, Jesper V. Olsen, Leon H.F. Mullenders, Alex Pines
Publikováno v:
Molecular and Cellular Biology, 31(24), 4964-4977
Molecular and Cellular Biology
Molecular and Cellular Biology
Cellular responses to DNA-damaging agents involve the activation of various DNA damage signaling and transduction pathways. Using quantitative and high-resolution tandem mass spectrometry, we determined global changes in protein level and phosphoryla
Autor:
Mischa G. Vrouwe, Leon H.F. Mullenders
Publikováno v:
The DNA Damage Response: Implications on Cancer Formation and Treatment ISBN: 9789048125609
A network of DNA damage surveillance systems warrants genomic stability under conditions where cells and organisms are continuously exposed to DNA damaging agents. This network includes DNA repair pathways, but also signaling pathways that activate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6c7b74e81954ed9261cd2b02d50d69
https://doi.org/10.1007/978-90-481-2561-6_11
https://doi.org/10.1007/978-90-481-2561-6_11
Autor:
Marcel M.A.M. Mannens, Elhaam Elghalbzouri-Maghrani, Firouz Darroudi, Mischa G. Vrouwe, Egbert J.W. Redeker, Barbara C. Godthelp, Leon H.F. Mullenders, Peter Schouten, Zahurul A. Bhuiyan, Matty Meijers, Albert Pastink
Publikováno v:
Human molecular genetics, 16(12), 1478-1487. Oxford University Press
Cornelia de Lange syndrome (CdLS) is a rare dominantly inherited multisystem disorder affecting both physical and mental development. Heterozygous mutations in the NIPBL gene were found in about half of CdLS cases. Scc2, the fungal ortholog of the NI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7474912d9187fa5556477077e09f560
https://pure.amc.nl/en/publications/increased-dna-damage-sensitivity-of-cornelia-de-lange-syndrome-cells-evidence-for-impaired-recombinational-repair(d21feb3e-66e2-4860-a05d-44a4e2db0224).html
https://pure.amc.nl/en/publications/increased-dna-damage-sensitivity-of-cornelia-de-lange-syndrome-cells-evidence-for-impaired-recombinational-repair(d21feb3e-66e2-4860-a05d-44a4e2db0224).html
Autor:
Jan H.J. Hoeijmakers, Petros Kolovos, Frank Grosveld, Maria Tresini, Wilfred F. J. van IJcken, Mischa G. Vrouwe, René H. Medema, Jurgen A. Marteijn, Jeroen Demmers, Wim Vermeulen, Loes Snijder, Daniël O. Warmerdam, Leon H.F. Mullenders
Publikováno v:
Nature, 523(7558), 53-+. Nature Publishing Group
Nature, 523(7558), 53
Nature, 523(7558), 53. Nature Publishing Group
Nature, 523(7558), 53
Nature, 523(7558), 53. Nature Publishing Group
In response to DNA damage, tissue homoeostasis is ensured by protein networks promoting DNA repair, cell cycle arrest or apoptosis. DNA damage response signalling pathways coordinate these processes, partly by propagating gene-expression-modulating s