Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Misato Uraki"'
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 41:301-307
An in situ perfused rat liver system is useful for studying the hepatic disposition of drugs and their metabolites. However, the effects of the perfusion conditions on drug disposition are unclear. We examined the effects of conditions such as flow r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26d8f2602db4ccfc8f38a23372c4ce1
https://doi.org/10.1007/s13318-015-0259-4
https://doi.org/10.1007/s13318-015-0259-4
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 47(11)
1. The effects of adjuvant-induced arthritis (AA) on the stereoselective hepatic disposition and chiral inversion of "profens" have scarcely been investigated. Ibuprofen (IB) undergoes unidirectional chiral inversion from R-IB to S-IB and is metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01542d64d81ce93843181c3c4981d26
https://pubmed.ncbi.nlm.nih.gov/27774827
https://pubmed.ncbi.nlm.nih.gov/27774827
Publikováno v:
Journal of pharmaceutical sciences. 106(4)
The reactive metabolites of diclofenac (DF) such as 1-O-acyl glucuronide (DF-Glu) are hypothesized to result in idiosyncratic hepatotoxicity. However, it is unclear whether inflammation affects the hepatic disposition of DF and its metabolites. To cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffd977769eacb3f52bf7d89e437396a
https://pubmed.ncbi.nlm.nih.gov/28062205
https://pubmed.ncbi.nlm.nih.gov/28062205
Publikováno v:
Xenobiotica. 38:1410-1421
1. The effects of adjuvant-induced arthritis on the chiral inversion of 'profens', a type of non-steroidal anti-inflammatory drug, have hardly been investigated. The authors investigated the effects of adjuvant-induced arthritis on the chiral inversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de8d481c1320f77b3b8f49ac2368aad
https://doi.org/10.1080/00498250802483768
https://doi.org/10.1080/00498250802483768
Autor:
Ayami Ito, Ayano Yamada, Satoshi Uno, Misato Uraki, Yuki Shinozaki, Masahiro Iwaki, Atsushi Kawase
Publikováno v:
Biopharmaceuticsdrug disposition. 30(1)
In this study, a real-time reverse transcription-polymerase chain reaction was used to determine the effects of adjuvant-induced arthritis (AA) on the amounts of mRNA of 12 types of rat ATP-binding cassette (ABC) and solute carrier (SLC) transporters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73a0b4a81c8a3cf85f198c854cd3d7c
https://pubmed.ncbi.nlm.nih.gov/19152228
https://pubmed.ncbi.nlm.nih.gov/19152228