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Autor:
Yoshiyuki, Taoda, Toshiyuki, Akiyama, Kenji, Tomita, Misato, Fujiwara-Kitamura, Yoshinori, Tamura, Takashi, Kawasuji, Eriko, Matsuoka, Erika, Akihisa, Takahiro, Seki, Tomokazu, Yoshinaga
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 64:128664
We have been conducting exploratory research to develop human immunodeficiency virus type-1 (HIV-1) integrase-LEDGF/p75 allosteric inhibitors (INLAIs). Here, we report on a newly designed compound with a tricyclic scaffold that shows promise as an in