Shedding of N-acetylglucosaminyltransferase-V is regulated by maturity of cellular N-glycan

Autor: Tetsuya Hirata, Misaki Takata, Yuko Tokoro, Miyako Nakano, Yasuhiko Kizuka

Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)

Cleavage of the glycan-branching enzyme N-acetylglucosaminyltransferase-V (GnT-V) by signal peptide peptidase-like 3 (SPPL3) protease and extracellular secretion of active glycan GnT-V depend on GnT-V’s own glycosylation state.

Externí odkaz: https://doaj.org/article/02b58c5f888d4facb73bd2211aa34b20

Peptide Sequence Mapping around Bisecting GlcNAc-Bearing N-Glycans in Mouse Brain

Autor: Yoichiro Harada, Sushil Kumar Mishra, Yuki Ohkawa, Naoyuki Taniguchi, Yasuhiko Kizuka, Haruna Akatsuka, Misaki Takata, Emi Ito, Miyako Nakano

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8579, p 8579 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 16; Pages: 8579

N-glycosylation is essential for many biological processes in mammals. A variety of N-glycan structures exist, of which, the formation of bisecting N-acetylglucosamine (GlcNAc) is catalyzed by N-acetylglucosaminyltransferase-III (GnT-III, encoded by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4de0203ad01f2b7f523f1a5fd6daae9
https://doi.org/10.3390/ijms22168579