Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Misaki Sugai"'
Autor:
Akira Sakai, Naohiro Tsuyama, Tetsuya Ohira, Misaki Sugai-Takahashi, Takashi Ohba, Yusuke Azami, Yoshiko Matsumoto, Iwadate Manabu, Satoshi Suzuki, Maki Sato, Mitsuaki Hosoya, Tetsuo Ishikawa, Shinichi Suzuki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract To investigate the effects of radiation exposure due to the Fukushima nuclear power plant accident, following the disaster Fukushima Prefecture launched thyroid ultrasound examinations of residents who were generally younger than 18 years at
Externí odkaz:
https://doaj.org/article/7e389e3a18d048829a717b88fbaf290c
Autor:
Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Daisuke Iizuka, Misaki Sugai-Takahashi, Moe Muramatsu, Akira Sakai
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-15 (2022)
Abstract Background The DNA damage response (DDR) is a mechanism that protects cells against radiation-induced oxidative DNA damage by causing cell cycle arrest and apoptosis. TP63 is a member of the tumour suppressor TP53 gene family, and ΔNp63α,
Externí odkaz:
https://doaj.org/article/9aa9bd7fe56b4073953ba20e26d25001
Autor:
Yusuke Azami, Naohiro Tsuyama, Yu Abe, Misaki Sugai-Takahashi, Ken-ichi Kudo, Akinobu Ota, Karnan Sivasundaram, Moe Muramatsu, Tomonari Shigemura, Megumi Sasatani, Yuko Hashimoto, Shigehira Saji, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Multiple myeloma (MM) cells are derived from mature B cells based on immunoglobulin heavy chain (IgH) gene analysis. The onset of MM is often caused by a reciprocal chromosomal translocation (cTr) between chr 14 with IgH and chr 11 with CCND
Externí odkaz:
https://doaj.org/article/81747abd10d746a997909ec4057a1be8
Autor:
Tsuyoshi Matsuoka, Toshifumi Yodoshi, Misaki Sugai, Masato Hiyane, Takashi Matsuoka, Hideki Akeda, Masaharu Ohfu, Satoshi Komoto, Koki Taniguchi
Publikováno v:
Case Reports in Pediatrics, Vol 2013 (2013)
We report a case of mild encephalopathy with a reversible splenial lesion (MERS) associated with acute gastroenteritis caused by rotavirus (RV) infection. The patient (male, 4 years and 3 months old) was admitted to our hospital for diarrhea and afeb
Externí odkaz:
https://doaj.org/article/831ac6738f744f4e8f3290f82ca7a2a7
Autor:
Masafumi Onodera, Misaki Sugai-Takahashi, Yuko Hashimoto, Tomonari Shigemura, Karnan Sivasundaram, Yusuke Azami, Akinobu Ota, Shigehira Saji, Megumi Sasatani, Ichiro Hanamura, Akira Sakai, Yu Abe, Kenji Kamiya, Naohiro Tsuyama, Ken-ichi Kudo, Takayuki Ikezoe, Moe Muramatsu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Multiple myeloma (MM) cells are derived from mature B cells based on immunoglobulin heavy chain (IgH) gene analysis. The onset of MM is often caused by a reciprocal chromosomal translocation (cTr) between chr 14 with IgH and chr 11 with CCND1. We pro
Autor:
Takayuki Ikezoe, Kenji Kamiya, Moe Muramatsu, Megumi Sasatani, Karnan Sivasundaram, Yuko Hashimoto, Naohiro Tsuyama, Akira Sakai, Masafumi Onodera, Akinobu Ota, Yusuke Azami, Misaki Sugai, Ichiro Hanamura, Yu Abe, Miwa Fukami, Ken-ichi Kudo, Shigehira Saji
Publikováno v:
Blood. 138:4711-4711
Multiple myeloma (MM) cells are derived from mature B cells based on immunoglobulin heavy chain (IgH) gene analysis. The onset of MM is often caused by a reciprocal chromosomal translocation (cTr) between chr 14 with IgH and chr 11 with CCND1. We pro
Autor:
Moe Muramatsu, Masafumi Onodera, Ichiro Hanamura, Misaki Sugai, Yusuke Azami, Yuko Hashimoto, Takayuki Ikezoe, Megumi Sasatani, Ken-ichi Kudo, Kenji Kamiya, Akira Sakai, Naohiro Tsuyama, Sivasundaram Karnan, Akinobu Ota, Yu Abe, Tomonari Shigemura
Publikováno v:
Blood. 136:18-19
The cellular origin of multiple myeloma (MM) has not yet been identified. Based on immunoglobulin heavy chain (IgH) gene analysis, myeloma cells are derived from mature B cells. Chromosomal aberrations such as trisomy and chromosomal translocation (c
Autor:
Yukari Yanai, Misaki Sugai, Fumihiko Kawamura, Yu Abe, Atsushi Katafuchi, Akira Sakai, Kenji Kamiya, Naohiro Tsuyama, Aki Yanagi
Publikováno v:
Oncology Letters
Chromosomal translocation is a key process in the oncogenic transformation of somatic cells. Previously, artificial induction of chromosomal translocation was performed using homologous recombination-mediated loxP labeling of target regions followed
Autor:
Naohiro Tsuyama, Karnan Sivasundaram, Akira Sakai, Ichiro Hanamura, Megumi Sasatani, Tomonari Shigemura, Yusuke Azami, Yuko Hashimoto, Yu Abe, Yukari Yanai, Akinobu Ota, Aki Yanagi, Misaki Sugai, Masafumi Onodera, Moe Muramatsu, Takayuki Ikezoe, Kenji Kamiya
Publikováno v:
Blood. 134:3057-3057
The cellular origin of multiple myeloma (MM) has not ben identified. Based on the results of transplantation experiments using bone marrow samples from MM patients in immunodeficient mice, so-called myeloma stem cells have been inferred to be present
Autor:
Akira Sakai, Takayuki Ikezoe, Yu Abe, Naohiro Tsuyama, Megumi Sasatani, Kenji Kamiya, Akinobu Ota, Aki Yanagi, Masafumi Onodera, Yukari Yanai, Karnan Sivasundaram, Tomonari Shigemura, Misaki Sugai, Ichiro Hanamura
Publikováno v:
Blood. 132:1896-1896
We previously established normal B cell-derived induced pluripotent stem cells (BiPSCs; BiPSC13 and MIB2-6). BiPSCs are known to maintain VDJ rearrangement of the IgH gene, and they can be induced by the tet-off system to express activation-induced c