Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Misa Mizumori"'
Autor:
Maggie Ham, Joonho Wang, Chikako Watanabe, Jonathan D. Kaunitz, Paul H. Guth, Takanari Nakano, Misa Mizumori, Yasutada Akiba, Takuya Inoue, Eli Engel
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 335:607-613
Luminal ATP increases duodenal bicarbonate secretion (DBS) via brush border P2Y receptors. Because ATP is sequentially dephosphorylated to adenosine (ADO) and the brush border highly expresses adenosine deaminase (ADA), we hypothesized that luminal [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda5504395c1ce405cf867e41d0ca613
https://doi.org/10.1124/jpet.110.171520
https://doi.org/10.1124/jpet.110.171520
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G781-G791
Presence of taste receptor families in the gastrointestinal mucosa suggests a physiological basis for local and early detection of a meal. We hypothesized that luminal l-glutamate, which is the primary nutrient conferring fundamental umami or protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076caf2109646d9641a714c5542079c3
https://doi.org/10.1152/ajpgi.90605.2008
https://doi.org/10.1152/ajpgi.90605.2008
Publikováno v:
The Journal of Physiology. 587:3651-3663
Regulation of localized extracellular pH (pHo) maintains normal organ function. An alkaline microclimate overlying the duodenal enterocyte brush border protects the mucosa from luminal acid. We hypothesized that intestinal alkaline phosphatase (IAP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::299828ae0cf8b72f95b640876f9e6230
https://doi.org/10.1113/jphysiol.2009.172270
https://doi.org/10.1113/jphysiol.2009.172270
Autor:
Jonathan D. Kaunitz, Eli Engel, Tetsu Takeuchi, Misa Mizumori, Claudiu T. Supuran, Paul H. Guth, Shu Lim, Paul W. N. Lee, Justin G. Meyerowitz, Yasutada Akiba
Publikováno v:
The Journal of Physiology. 573:827-842
The duodenum must absorb ∼450 mmol of H+ per 24 h in order to decrease [H+] of the luminal content by 6 log orders over its 15 cm length (Feldman & Colturi, 1984). HCl in the duodenal lumen is neutralized by HCO3− secreted by the pancreas and duo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::028b69606abd792729a817e737244067
https://doi.org/10.1113/jphysiol.2006.107581
https://doi.org/10.1113/jphysiol.2006.107581
Autor:
Tetsu Takeuchi, Soichiro Miura, Hiromasa Ishii, Keita Uehara, Hiromasa Nakamizo, Ryota Hokari, Hajime Higuchi, Masayuki Adachi, Misa Mizumori, Hiroshi Kishikawa, Lin Wang
Publikováno v:
Digestive Diseases and Sciences. 47:2070-2078
Phorbol esters induce inflammation in rodents by activating protein kinase C. We determined whether nuclear factor-kappaB (NF-kappaB) and tumor necrosis factor-alpha (TNF-alpha) play role in the formation of gastric ulcer induced by phorbol-12-myrist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b35ad182cac92c3cf015e8a3d00edbd9
https://doi.org/10.1023/a:1019633114854
https://doi.org/10.1023/a:1019633114854
Autor:
Fukiko, Kawai, Satoshi, Otani, Tomohiko, Sano, Misa, Mizumori, Hitoshi, Kurata, Naoaki, Dan, Hiroyuki, Uetake, Kenichi, Sugihara, Mamoru, Watanabe
Publikováno v:
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 107(2)
A 52-year-old man underwent abdominoperineal resection of the rectum, a partial hepatectomy, and intrahepatic arterial infusion chemotherapy for rectal cancer and liver metastases in 2001. Due to recurrent liver metastases, additional hepatectomies w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ad11fdb89f60de1d7780bf09a2fa694
https://pubmed.ncbi.nlm.nih.gov/20134127
https://pubmed.ncbi.nlm.nih.gov/20134127
Publikováno v:
Mizumori, Misa; Akiba, Yasutada; & Kaunitz, Jonathan D.(2009). Lubiprostone Stimulates Duodenal Bicarbonate Secretion in Rats. Digestive Diseases and Sciences, 54(10), pp 2063-2069. doi: 10.1007/s10620-009-0907-0. Retrieved from: http://www.escholarship.org/uc/item/85n4t2hz
Digestive Diseases and Sciences
Digestive Diseases and Sciences
Background Lubiprostone, a bicyclic fatty acid, is used for the treatment of chronic constipation. No published study has addressed the effect of lubiprostone on intestinal ion secretion in vivo. Aim The aim of this study was to test the hypothesis t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7b1395b135f65761ef807de0ecd6f6
http://www.escholarship.org/uc/item/85n4t2hz
http://www.escholarship.org/uc/item/85n4t2hz
Publikováno v:
The Journal of physiology. 587(Pt 14)
Regulation of localized extracellular pH (pH(o)) maintains normal organ function. An alkaline microclimate overlying the duodenal enterocyte brush border protects the mucosa from luminal acid. We hypothesized that intestinal alkaline phosphatase (IAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd49d333cb457c0055d9bc4dc580ce1c
https://pubmed.ncbi.nlm.nih.gov/19602628
https://pubmed.ncbi.nlm.nih.gov/19602628
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 294(6)
We hypothesized that the function of duodenocyte apical membrane acid-base transporters are essential for H+absorption from the lumen. We thus examined the effect of inhibition of Na+/H+exchanger-3 (NHE3), cystic fibrosis transmembrane regulator (CFT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a0db7b18d4347b9eed0f837a801aee
https://pubmed.ncbi.nlm.nih.gov/18420826
https://pubmed.ncbi.nlm.nih.gov/18420826
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e423c523f603648b8d2ae0b409a9d959
https://doi.org/10.1096/fasebj.22.1_supplement.935.13
https://doi.org/10.1096/fasebj.22.1_supplement.935.13