Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Misa, Nguyen"'
Autor:
Mohammad Asikur Rahman, Grace Yang, Judy Lee, Misa Nguyen, Young-Woo Nam, Meng Cui, Miao Zhang, Razan Orfali, Naglaa Salem El-Sayed
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: In the activated state of small-conductance Ca(2+)-activated potassium (K(Ca) 2) channels, calmodulin interacts with the HA/HB helices and the S4-S5 linker. CyPPA potentiates K(Ca) 2.2a and K(Ca) 2.3 channel activity but not t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b2468662e99ca8ed6786ee0f6b6f12
https://doi.org/10.1111/bph.15676
https://doi.org/10.1111/bph.15676
Autor:
Adam Viegas, Khalid Zoghebi, Simin Rahighi, Keykavous Parang, Razan Orfali, Meng Cui, Young-Woo Nam, Misa Nguyen, Miao Zhang, Eman H M Mohammed
Publikováno v:
Acta Physiologica. 231
Aim Small-conductance Ca2+ -activated potassium (SK) channels are activated exclusively by increases in intracellular Ca2+ that binds to calmodulin constitutively associated with the channel. Wild-type SK2 channels are activated by Ca2+ with an EC50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3312b5fde71c7232d3183ccc03e127f3
https://doi.org/10.1111/apha.13552
https://doi.org/10.1111/apha.13552
Autor:
Young-Woo, Nam, Meng, Cui, Razan, Orfali, Adam, Viegas, Misa, Nguyen, Eman H M, Mohammed, Khalid A, Zoghebi, Simin, Rahighi, Keykavous, Parang, Miao, Zhang
Publikováno v:
Acta physiologica (Oxford, England). 231(1)
Small-conductance CaSite-directed mutagenesis, electrophysiological recordings and molecular dynamic (MD) simulations were utilized.Mutations that decrease hydrophobicity at the HA-S4-S5 interface lead to CaThe electrophysiological data and MD simula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f60cd66dabee2941bcc7afd96f7f2318
https://pubmed.ncbi.nlm.nih.gov/33119956
https://pubmed.ncbi.nlm.nih.gov/33119956