Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Misa, Mochizuki"'
Autor:
Ryoji Ito, Yusuke Ohno, Yunmei Mu, Yuyo Ka, Shuko Ito, Maiko Emi-Sugie, Misa Mochizuki, Kenji Kawai, Motohito Goto, Tomoyuki Ogura, Riichi Takahashi, Akira Niwa, Tatsutoshi Nakahata, Mamoru Ito
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Human hematopoietic stem cell (HSC)-transferred humanized mice are valuable models for exploring human hematology and immunology. However, sufficient recapitulation of human hematopoiesis in mice requires large quantities of enriched human C
Externí odkaz:
https://doaj.org/article/5fb3c7fe2ac54a79a530db9b5302a07c
Autor:
Ikumi Katano, Asami Hanazawa, Iyo Otsuka, Takuya Yamaguchi, Misa Mochizuki, Kenji Kawai, Ryoji Ito, Motohito Goto, Takahiro Kagawa, Takeshi Takahashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer in the clinic. Further discovery of novel drugs or therapeutic protocols that enhance efficacy requires reliable animal models that recapitulate human immune res
Externí odkaz:
https://doaj.org/article/b20ff092b5244208bc65b09380250c63
Autor:
Takuya Yamaguchi, Ikumi Katano, Iyo Otsuka, Ryoji Ito, Misa Mochizuki, Motohito Goto, Takeshi Takahashi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite recent advances in immunodeficient mouse models bearing human red blood cells (hRBCs), the elimination of circulating hRBCs by residual innate immune systems remains a significant challenge. In this study, we evaluated the role of mouse compl
Externí odkaz:
https://doaj.org/article/21811b9530d34276b0c169803db5834e
Autor:
Yuki Yoshimura, Kazuomi Nakamura, Misako Seno, Misa Mochizuki, Kenji Kawai, Satoshi Koba, Tatsuo Watanabe
Publikováno v:
Experimental Animals. 72:95-102
Autor:
Yuki, Yoshimura, Kazuomi, Nakamura, Misako, Seno, Misa, Mochizuki, Kenji, Kawai, Satoshi, Koba, Tatsuo, Watanabe
Publikováno v:
Experimental animals.
c-Fos is a useful marker gene of neuron activation for neuroscience and physiology research. The mechanism and function of neural networks have been elucidated using c-Fos reporter knock-in (KI) mice, but the small size of the mice makes it difficult
Autor:
Riichi Takahashi, Jochen Welcker, Yuyo Ka, Kayo Tomiyama, Misa Mochizuki, Ryoji Ito, Taichi Yamamoto, Tomoyuki Ogura, Motohito Goto, Mamoru Ito, Kenji Kawai, Ikumi Katano, Eiko Nishinaka
Publikováno v:
Immunology Letters. 229:55-61
Humanized mice are widely used to study the human immune system in vivo and develop therapies for various human diseases. Human peripheral blood mononuclear cells (PBMC)-engrafted NOD/Shi-scid IL2rγnull (NOG) mice are useful models for characterizat
Autor:
Ryoji Ito, Ikumi Katano, Immanuel W.H. Kwok, Lai Guan Ng, Miyuki Ida-Tanaka, Yusuke Ohno, Yunmei Mu, Hanako Morita, Eiko Nishinaka, Chiyoko Nishime, Misa Mochizuki, Kenji Kawai, Tay Hui Chien, Zhao Yunqian, Fan Yiping, Liew Hui Hua, Teja Celhar, Jerry Kok Yen Chan, Takeshi Takahashi, Motohito Goto, Tomoyuki Ogura, Riichi Takahashi, Mamoru Ito
Publikováno v:
Cell Reports. 41:111841
Neutrophils are critical mediators during the early stages of innate inflammation in response to bacterial or fungal infections. A human hematopoietic system reconstituted in humanized mice aids in the study of human hematology and immunology. Howeve
Autor:
Masahiko, Yasuda, Ritsuki, Uchida, Yoko, Kamai, Hanako, Morita, Mai, Tanaka, Tomoko, Ishida, Misa, Mochizuki, Masafumi, Yamamoto, Nobuhito, Hayashimoto, Kenji, Kawai
Publikováno v:
Experimental animals. 71(1)
Pneumocystis (P.) carinii is known to cause fatal pneumonia in immunocompromised rats. Cases of P. carinii interstitial pneumonia in immunocompetent rats have been shown histologically to present with perivascular lymphoid cuffs, which have previousl
Autor:
Iyo Otsuka, Motohito Goto, Takuya Yamaguchi, Misa Mochizuki, Ikumi Katano, Ryoji Ito, Takeshi Takahashi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Despite recent advances in immunodeficient mouse models bearing human red blood cells (hRBCs), the elimination of circulating hRBCs by residual innate immune systems remains a significant challenge. In this study, we evaluated the role of mouse compl
Autor:
Takahiro Kagawa, Motohito Goto, Kenji Kawai, Takeshi Takahashi, Ryoji Ito, Iyo Otsuka, Ikumi Katano, Takuya Yamaguchi, Asami Hanazawa, Misa Mochizuki
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer in the clinic. Further discovery of novel drugs or therapeutic protocols that enhance efficacy requires reliable animal models that recapitulate human immune responses to