Výsledky vyhledávání - "Mirza Suljagic"

Akademický článek

Curcumin Decreases Viability and Inhibits Proliferation of Imatinib-Sensitive and Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines

Autor: Esma Bilajac, Lejla Mahmutović, Una Glamočlija, Amar Osmanović, Altijana Hromić-Jahjefendić, Murtaza M. Tambuwala, Mirza Suljagić

Publikováno v: Metabolites, Vol 13, Iss 1, p 58 (2022)

Chronic myeloid leukemia (CML) is a myeloproliferative haematological malignancy characterized by constitutive activation of BCR-ABL1 tyrosine kinase in the majority of patients. BCR-ABL1 expression activates signaling pathways involved in cell proli

Externí odkaz: https://doaj.org/article/e759d15870f54a63884596b104ed4850

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Akademický článek

Metformin and Thymoquinone Synergistically Inhibit Proliferation of Imatinib-Resistant Human Leukemic Cells

Autor: Una Glamoclija, Lejla Mahmutovic, Esma Bilajac, Violeta Soljic, Katarina Vukojevic, Mirza Suljagic

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Chemotherapy resistance is one of the major challenges in cancer treatment, including leukemia. A massive array of research is evaluating combinations of drugs directed against different intracellular signaling molecules to overcome cancer resistance

Externí odkaz: https://doaj.org/article/e4620f43516a4b5bb51f86a13a6db159

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The Predictive Significance of Metastasis-Associated in Colon Cancer-1 (MACC1) in Primary Breast Cancer

Autor: Jasminka, Prguda-Mujic, Karin, Milde-Langosch, Volkmar, Mueller, Mirza, Suljagic, Jozo, Coric, Daria, Ler

Publikováno v: Annals of clinical and laboratory science. 48(2)

Metastasis-Associated in Colon Cancer-1(MACC1) was first identified as a transcriptional activator of the HGF/MET pathway. Deregulation of HGF/MET signaling is reported as a prognostic marker for tumorigenesis, early stage invasion, and metastasis wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d652e3cdeeeb17dc9701e8c32c564162
https://pubmed.ncbi.nlm.nih.gov/29678846

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Autoencoder-aided measurement of concentration from a single line of speckle

Autor: Bernd Dammann, Mirza Suljagic, Kenan Šehić, Emir Karamehmedovic, Mirza Karamehmedovic

Publikováno v: Karamehmedović, M, Sehic, K, Dammann, B, Suljagić, M & Karamehmedović, E 2019, ' Autoencoder-aided measurement of concentration from a single line of speckle ', Optics Express, vol. 27, no. 20, pp. 29098-29123 . https://doi.org/10.1364/OE.27.029098

We demonstrate that a single 6mm line sample of simulated near-field speckleintensity suffices for accurate estimation of the concentration of dielectric micro-particles over a range from 104 to 6 · 106 particles per ml. For this estimation, we anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a04a4b12ea0ad96a47d5e9286bae8b5
https://doi.org/10.1364/oe.27.029098

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Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells

Autor: Mirza Suljagic, Luca Laurenti, Dimitar G. Efremov, Michela Tarnani, Sami N. Malek, Muhammad Mansoor Alam

Publikováno v: Leukemia. 24(12)

The PI3K/Akt pathway is activated in response to various microenvironmental stimuli that regulate the survival and proliferation of chronic lymphocytic leukemia (CLL) B-cells, including triggering of the B-cell receptor (BCR). Although this pathway i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6f6381d2f69c196cdd5a289ad27546
https://pubmed.ncbi.nlm.nih.gov/20861921

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The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling

Autor: Mirza Suljagic, Dimitar G. Efremov, Pablo G. Longo, Emerald Perlas, Giuseppe Leone, Luca Laurenti, Sara Bennardo

Publikováno v: Blood. 116(23)

Inhibition of antigen-dependent B-cell receptor (BCR) signaling is considered a promising therapeutic approach in chronic lymphocytic leukemia (CLL), but experimental in vivo evidence to support this view is still lacking. We have now investigated wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91574509b4d68d85ed09e914fcf92dde
https://pubmed.ncbi.nlm.nih.gov/20716772

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The Nature of the Antigen Determines Leukemia Development and Behavior in the Eμ-TCL1 Transgenic Mouse Model of CLL

Autor: Dimitar G. Efremov, Julia Eckl-Dorna, Daniel Bilbao, Stephen H. Clarke, Hongsheng Wang, Stefano Iacovelli, Richard J. Cornall, Mirza Suljagic, Stefania Gobessi, Carlo M. Croce, Sara Bennardo

Publikováno v: Blood. 120:181-181

Abstract 181 Studies conducted over the past decade have revealed a strong association between the mutational status of the immunoglobulin heavy-chain variable region (IGHV) genes and clinical course in patients with chronic lymphocytic leukemia (CLL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6177ccc830632e66389d126aca71178b
https://doi.org/10.1182/blood.v120.21.181.181

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The Syk Inhibitor R788 (FosD) Inhibits Tumor Growth in the TCL1 Transgenic Mouse Model of CLL by Blocking Antigen-Dependent BCR Signaling

Autor: Dimitar G. Efremov, Mirza Suljagic, Pablo G. Longo, Luca Laurenti

Publikováno v: Blood. 114:887-887

Abstract 887 CLL B-cells depend on various signals from the microenvironment for survival and proliferation. Among these, antigenic stimuli that are propagated through the B-cell receptor (BCR) are considered particularly important for the developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4af2cbff35d2dc9dbee5a2e6602b4ff4
https://doi.org/10.1182/blood.v114.22.887.887

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Chronic Lymphocytic Leukemia B-Cells Lack or Express Markedly Reduced Levels of the Phosphatase PHLPP, Which Regulates B-Cell Receptor Induced AKT Activation

Autor: Luca Laurenti, Mirza Suljagic, Dimitar G. Efremov, Pablo G. Longo, Sami N. Malek, Muhammad Mansoor Alam

Publikováno v: Blood. 112:2080-2080

The PI3K/AKT pathway plays a central role in regulating cellular growth and survival. This pathway is activated by signals derived from various receptors and is tightly regulated through the action of several phosphatases, including SHIP and PTEN, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87259b508599bdf89980f6e578776456
https://doi.org/10.1182/blood.v112.11.2080.2080

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