Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mirza Peljto"'
Autor:
Tulsi Patel, Christopher Reeder, Esteban O. Mazzoni, Laurie A. Boyer, Richard A. Young, Hynek Wichterle, Scott McCuine, Seraphim R. Thornton, Shaun Mahony, David K. Gifford, Mirza Peljto
Publikováno v:
Nature neuroscience
Hox genes controlling motor neuron subtype identity are expressed in rostrocaudal patterns that are spatially and temporally collinear with their chromosomal organization. Here we demonstrate that Hox chromatin is subdivided into discrete domains tha
Autor:
Famke Aeffner, G. David Young, Maryam Jangani, Mirza Peljto, Joseph S. Krueger, Joshua C. Black, Justin K Major, Michael O Ports, Nathan T. Martin
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 96(12)
Tissue image analysis (tIA) is emerging as a powerful tool for quantifying biomarker expression and distribution in complex diseases and tissues. Pancreatic ductal adenocarcinoma (PDAC) develops in a highly complex and heterogeneous tissue environmen
Autor:
Lance C. Kam, Hynek Wichterle, Mackenzie W. Amoroso, Mirza Peljto, Peng Shi, Stéphane Nedelec
Publikováno v:
The Journal of Neuroscience. 32:1496-1506
Formation of functional motor circuits relies on the ability of distinct spinal motor neuron subtypes to project their axons with high precision to appropriate muscle targets. While guidance cues contributing to motor axon pathfinding have been ident
Autor:
Hynek Wichterle, Mirza Peljto
Publikováno v:
Current Opinion in Neurobiology. 21:43-51
Richness of neural circuits and specificity of neuronal connectivity depend on the diversification of nerve cells into functionally and molecularly distinct subtypes. Although efficient methods for directed differentiation of embryonic stem cells (ES
Publikováno v:
Cell Stem Cell. 7:355-366
SummaryCultured ESCs can form different classes of neurons, but whether these neurons can acquire specialized subtype features typical of neurons in vivo remains unclear. We show here that mouse ESCs can be directed to form highly specific motor neur
Autor:
Hynek Wichterle, Mirza Peljto
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493926800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f141608c1c448c22128842c3a124f3be
https://doi.org/10.1007/7653_2014_15
https://doi.org/10.1007/7653_2014_15
Autor:
Holger Lange, Mirza Peljto, Joseph S. Krueger, Steven J. Potts, G. David Young, Nicholas D. Landis
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493926800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b99cec74fbffa1582f5e25c77a8410b
https://doi.org/10.1007/7653_2014_21
https://doi.org/10.1007/7653_2014_21
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493926800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab984dc679b9c8df2c7380688eb8e347
https://doi.org/10.1007/7653_2014_19
https://doi.org/10.1007/7653_2014_19
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 482
A growing number of specific cell types have been successfully derived from embryonic stem cells (ES cells), including a variety of neural cells. In vitro generated cells need to be extensively characterized to establish functional equivalency with t
Autor:
Mirza Peljto, Hynek Wichterle
Publikováno v:
Current Protocols in Stem Cell Biology
Controlled differentiation of embryonic stem (ES) cells into clinically relevant cell types is a fundamental goal of stem cell research. This unit describes one of the most efficient protocols for conversion of mouse ES cells into a defined type of n