Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mirxan Farizyan"'
Publikováno v:
Chemical Science. 14:4357-4362
We describe the sterically controlled iodination of arenes through an isodesmic C–H/C–I bond metathesis approach. The protocol gives direct access to a complementary product spectrum with respect to traditional methods.
Aryl iodides are key motifs in organic chemistry due to their versatility as linchpins in metal-mediated cross-coupling reactions for synthesis and drug discovery. These scaffolds are typically prepared indirectly from prefunctionalized starting mate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559e568d9aea6dfcdaabbc2c3ab105c5
https://doi.org/10.26434/chemrxiv-2023-6s3s1
https://doi.org/10.26434/chemrxiv-2023-6s3s1
Autor:
Philipp Wedi, Christian Mück-Lichtenfeld, Mirxan Farizyan, Klaus Bergander, Manuel van Gemmeren
Publikováno v:
Angewandte Chemie. 133:15770-15779
Publikováno v:
European Journal of Organic Chemistry. 2020:6318-6327
Publikováno v:
Angewandte Chemie (International Ed. in English)
The regioselective functionalization of heteroarenes is a highly attractive synthetic target due to the prevalence of multiply substituted heteroarenes in nature and bioactive compounds. Some substitution patterns remain challenging: While highly eff
We describe a palladium catalyzed non-directed late-stage deuteration of arenes. Key aspects include the use of D2O as a convenient and easily available deuterium source and the discovery of highly active N,N-bidentate ligands containing an N-acyl su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e25799a855d580baa8c2159654d5624
https://doi.org/10.33774/chemrxiv-2021-vtsnn-v2
https://doi.org/10.33774/chemrxiv-2021-vtsnn-v2
We describe a palladium catalyzed non-directed late-stage deuteration of arenes. Key aspects include the use of D2O as a convenient and easily available deuterium source and the discovery of highly active N,N-bidentate ligands containing an N-acyl su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432c29d87281bb3781ade90454b97d34
https://doi.org/10.26434/chemrxiv-2021-vtsnn
https://doi.org/10.26434/chemrxiv-2021-vtsnn
Autor:
Philipp Wedi, Mirxan Farizyan, Klaus Bergander, Christian Mück-Lichtenfeld, Manuel van Gemmeren
Palladium catalysts have recently been discovered that enable the directing group-free C–H activation and functionalization of arenes without requiring an excess of the arene substrate. By overcoming this long standing challenge, the resulting synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b75217b1e50c3ceb6842e46c9b0120
https://doi.org/10.26434/chemrxiv.10012025
https://doi.org/10.26434/chemrxiv.10012025
Autor:
Ken Yamazaki, Pablo Gabriel, Graziano Di Carmine, Julia Pedroni, Mirxan Farizyan, Trevor Hamlin, Darren J. Dixon
A new iridium-catalyzed reductive generation of both stabilized and unstabilized azomethine ylides and their application to functionalized pyrrolidine synthesis via [3+2] dipolar cycloaddition reactions is described. Proceeding under mild reaction co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8540bcb428661070670e083beb83bd7
https://doi.org/10.26434/chemrxiv.13587995.v2
https://doi.org/10.26434/chemrxiv.13587995.v2
Publikováno v:
Journal of the American Chemical Society
We describe a palladium-catalyzed nondirected late-stage deuteration of arenes. Key aspects include the use of D2O as a convenient and easily available deuterium source and the discovery of highly active N,N-bidentate ligands containing an N-acylsulf