Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Miruto Tanaka"'
Autor:
Miruto Tanaka, Shinsuke Nakamura, Tomohisa Sakaue, Takumi Yamamoto, Masashi Maekawa, Anri Nishinaka, Hiroto Yasuda, Kaori Yunoki, Yuji Sato, Masaaki Sawa, Kohichiro Yoshino, Masamitsu Shimazawa, Masahiko Hatano, Takeshi Tokuhisa, Shigeki Higashiyama, Hideaki Hara
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:927-942
Background: Endothelial cell activation is tightly controlled by the balance between VEGF (vascular endothelial cell growth factor) and Notch signaling pathway. VEGF destabilizes blood vessels and promotes neovascularization, which are common feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8e6ea50a3a87bc36ed2b747c223745
https://doi.org/10.1161/atvbaha.123.318987
https://doi.org/10.1161/atvbaha.123.318987
Publikováno v:
Current Neurovascular Research. 18:85-92
Background: Neovascular age-related macular degeneration (AMD) with choroidal neovascularization (CNV) is a leading cause of blindness in elderly people. Anti-vascular endothelial growth factor (anti-VEGF)-drugs are used to treat AMD patients; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6009456a0342f86ffa074b3afff9f1
https://doi.org/10.2174/1567202618666210518133634
https://doi.org/10.2174/1567202618666210518133634
Autor:
Wataru Otsu, Hideshi Tsusaki, Shinsuke Nakamura, Kodai Ishida, Tomohiro Yako, Miruto Tanaka, Hideaki Hara, Masamitsu Shimazawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:937-946
The corneal epithelium is continuously exposed to oxygen, light, and environmental substances. Excessive exposure to those stresses is thought to be a risk factor for eye diseases. Photokeratitis is damage to the corneal epithelium resulting in a pai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb581c2d311ed240a15b40945bd7a197
https://doi.org/10.1248/bpb.b21-00017
https://doi.org/10.1248/bpb.b21-00017
Autor:
Koichi Takahashi, Norifumi Tanida, Yohei Miyamoto, Yoshiki Kuse, Miruto Tanaka, Yuta Yoshino, Yuki Inoue, Hideaki Hara
Publikováno v:
BPB Reports. 4:1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908b051ccb98bce7299d25d20d0fb061
https://doi.org/10.1248/bpbreports.4.1_1
https://doi.org/10.1248/bpbreports.4.1_1
Publikováno v:
Biochemical and Biophysical Research Communications. 533:1406-1412
Dysregulation of endothelial cell proliferation and migration are hallmarks of angiogenic diseases. Among them, excessive ocular angiogenesis is a major cause of blindness. Vascular endothelial growth factor (VEGF)-VEGF receptor 2 (VEGFR2) signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee4d51ebe2097e3828c7a061202383b
https://doi.org/10.1016/j.bbrc.2020.10.032
https://doi.org/10.1016/j.bbrc.2020.10.032
Autor:
Anri Nishinaka, Miruto Tanaka, Kota Aoshima, Aika Kuriyama, Takahiro Sasaki, Wataru Otsu, Hiroto Yasuda, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara
Publikováno v:
The FASEB Journal. 36
Neovascular glaucoma (NVG) is caused by the formation of new blood vessels in the angle, iris, and cornea in retinal ischemic disease, such as proliferative diabetic retinopathy (PDR) and retinal vein occlusion (RVO), which can reduce the visual acui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96681f6b2646420ef6a06be3ebbf8d60
https://doi.org/10.1096/fj.202101917r
https://doi.org/10.1096/fj.202101917r
Autor:
Miruto Tanaka, Naoki Chinen, Masamitsu Shimazawa, Shiori Ando, Shinsuke Nakamura, Hideaki Hara
Publikováno v:
In Vivo. 34:3247-3254
Background/aim In spinal muscular atrophy (SMA), systemic deficiency of survival motor neurons (SMN) caused by loss or mutation of SMN1 leads to SMA symptoms. SMA was, for a long time, considered as a selective motor-neuron disease. However, accumula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d41cc3eb05719e49b4cfb366a52b2977
https://doi.org/10.21873/invivo.12161
https://doi.org/10.21873/invivo.12161
Autor:
Takumi Yamamoto, Tomomi Masuda, Miruto Tanaka, Hideaki Hara, Anri Nishinaka, Yae Hidaka, Takahiko Imai, Shinsuke Nakamura, Masamitsu Shimazawa, Yuki Inoue
Publikováno v:
The FASEB Journal. 35
Anti-vascular endothelial growth factor (VEGF) therapies are now the first-line treatment for many ocular diseases, but some patients are non-responders to these therapies. The purpose of this study was to determine whether the level of adiponectin i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1b7e4bfa549315a5209730654aa200
https://doi.org/10.1096/fj.202001740rr
https://doi.org/10.1096/fj.202001740rr
Autor:
Junko Ito, Yasuhiro Noda, Masamitsu Shimazawa, Hideaki Hara, Miruto Tanaka, Akiyoshi Kakita, Shinsuke Nakamura
Publikováno v:
International Journal of Medical Sciences
Amyotrophic lateral sclerosis (ALS) is a serious disease characterized by the degeneration of motor neurons resulting in muscle weakness and paralysis. The neuroendocrine polypeptide VGF is localized in the central nervous system and peripheral endoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67a943c11ffc71fb72854409ce1a802
https://pubmed.ncbi.nlm.nih.gov/32174778
https://pubmed.ncbi.nlm.nih.gov/32174778
Autor:
Anri Nishinaka, Masamitsu Shimazawa, Takumi Yamamoto, Miruto Tanaka, Shinsuke Nakamura, Koki Nitta, Hideaki Hara
Publikováno v:
Experimental Eye Research. 204:108453
Retinal vein occlusion (RVO) is an intractable eye disease that results in reduced visual acuity, associated with retinal ischemia, hemorrhage, and edema. RVO results in excessive ROS production in the retina, causing inflammation and retinal edema.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3354e0e460e9ab6cde0a2308cda3db93
https://doi.org/10.1016/j.exer.2021.108453
https://doi.org/10.1016/j.exer.2021.108453