Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mirta Canevari"'
Autor:
Paola Brun, Ignazio Castagliuolo, Mariano Schiavon, Fm Veronese, Mirta Canevari, Gianfranco Pasut, M Cardin
Publikováno v:
International Journal of Pharmaceutics. 368:171-177
Chronic inflammatory bowel diseases (IBDs) are still waiting for improved and innovative therapeutic treatments, which can overcome the limits of the current approaches. Since IBDs affect mainly the lower tract of the intestine, a localized therapy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8275ea10231d25052e84291f43e60c
https://doi.org/10.1016/j.ijpharm.2008.09.058
https://doi.org/10.1016/j.ijpharm.2008.09.058
Autor:
Ruth Duncan, Franco Bordin, Frazia Bettio, Andrea Guiotto, Fm Veronese, Mirta Canevari, Christine Marzano, Francesca Greco
Publikováno v:
Biomacromolecules. 7:3534-3541
Psoralens are well-known photosensitizers, and 8-methoxypsoralen and 4,5',8-trimethylpsoralen are widely used in photomedicine as "psoralens plus UVA therapy" (PUVA), in photopheresis, and in sterilization of blood preparations. In an attempt to impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf209118399e1b4e145ddea88b74e1c
https://doi.org/10.1021/bm060760n
https://doi.org/10.1021/bm060760n
Autor:
Akinobu Kurita, Olivier Lavanchy, Norimasa Kaneda, Mirta Canevari, Francesco M. Veronese, Andrea Guiotto, Takeshi Yaegashi, Takeshi Matsuzaki, Piero Orsolini, Seigo Sawada, Christine Deuschel
Publikováno v:
Journal of Medicinal Chemistry. 47:1280-1289
Despite the high antitumor activity of camptothecins, few derivatives have been developed and tested for human treatment of solid tumors, due to unpredictable toxicity mainly connected to their poor water solubility. We report the conjugation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071b0601ea367e5bba3066983254f8da
https://doi.org/10.1021/jm031072e
https://doi.org/10.1021/jm031072e
Efficient and chemoselective N-acylation of 10-amino-7-ethyl camptothecin with poly(ethylene glycol)
Autor:
Francesco M. Veronese, Christine Deuschel, Andrea Guiotto, Piero Orsolini, Seigo Sawada, Takeshi Yaegashi, Akinobu Kurita, Takeshi Matsuzaki, Norimasa Kaneda, Mirta Canevari, Olivier Lavanchy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:1803-1805
A new poly(ethylene glycol) (PEG) conjugate of 10-amino-7-ethyl camptothecin, a potent antitumor analogue of camptothecin, has been synthesized and preliminary in vivo tests have been performed. Successful chemoselective N-acylation of 10-amino-7-eth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73eae2e42fb80c167f7a130b735526e2
https://doi.org/10.1016/j.bmcl.2003.12.098
https://doi.org/10.1016/j.bmcl.2003.12.098
Autor:
Mirta Canevari, Stefano Moro, Francesco M. Veronese, Andrea Guiotto, Piero Orsolini, Michela Pozzobon
Publikováno v:
Bioorganicmedicinal chemistry. 12(19)
Branched poly(ethylene glycols) (PEG2) are nowadays widely used for protein and peptides bioconjugation, for their favourable properties (such as the ability to protect the protein surface in an 'umbrella like' fashion). The discovery that mPEG(2)-Ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4508052033cba6b0143e963cf5bfa6dc
https://pubmed.ncbi.nlm.nih.gov/15351387
https://pubmed.ncbi.nlm.nih.gov/15351387
Autor:
Mirta Canevari, Francesco M. Veronese, Riccardo Manganelli, Michela Pozzobon, Marino Scarin, Andrea Guiotto
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 58(1)
Nisin is a natural antimicrobial peptide produced by Lactococcus lactis and widely employed as food preservative. Its low solubility in neutral aqueous solutions, its instability at physiological pH and its rapid breakdown by proteolytic enzymes has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f528ea7c4e0c91a36d375e2ff3def04d
https://pubmed.ncbi.nlm.nih.gov/12595036
https://pubmed.ncbi.nlm.nih.gov/12595036