Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Miroslawa Szczepanska-Konkel"'
Autor:
Monika Sakowicz-Burkiewicz, Kornelia Sałaga-Zaleska, Maciej Jankowski, Kamil Dąbkowski, Ewelina Kreft, Miroslawa Szczepanska-Konkel
Publikováno v:
Journal of Vascular Research. 58:38-48
Diabetes through adenosine A1 receptor (A1R) and P2 receptors (P2Rs) may lead to disturbances in renal microvasculature. We investigated the renal microvascular response to Ap4A, an agonist of P2Rs, in streptozotocin-induced diabetic rats. Using lase
Publikováno v:
Pharmacological Reports. 68:71-74
Background Diabetic nephropathy is characterized by the dysfunction of renal microvasculature. The involvement of the P2X7 receptor, being a part of the purinergic system, is presumable in this process. The aim of our study was to investigate the P2X
Autor:
Marzena Domanska-Sadynica, Monika Zagorska, Anna Tyrańska-Fobke, Miroslawa Szczepanska-Konkel, Przemyslaw Zuratynski, Grzegorz Krzykowski, Zenon Jakubowski, Daniel Slezak, Krzysztof Sworczak, Marlena Robakowska, Jakub Kraszewski
Publikováno v:
Postępy Nauk Medycznych. 31
Autor:
Maciej Jankowski, Miroslawa Szczepanska-Konkel, Malgorzata Kasztan, Robert Kowalski, Ewelina Kreft
Publikováno v:
Nephrology Dialysis Transplantation. 27:3443-3448
BACKGROUND Kidney noradrenergic innervation regulates tubular function. Adenosine triphosphate (ATP)-a co-transmitter of norepinephrine-acts on purinoceptors, including ion channel receptor, P2X. P2X receptor agonists, α,β-methylene ATP (α,β-meAT
Autor:
E. Szamocka, Miroslawa Szczepanska-Konkel, Robert Kowalski, Maciej Jankowski, Stefan Angielski
Publikováno v:
Acta Physiologica. 202:193-201
Aim To investigate in vivo effects of P2X receptor activation on sodium and water excretion in urine. Methods The clearance experiments were carried out in anaesthetized rats during intravenous infusion (2 μmol kg(-1) + 20 nmol (kg min)(-1) , v = 40
Publikováno v:
Nephron Physiology. 106:p13-p18
Background/Aims: P1,P4-diadenosine tetraphosphate (Ap4A) is a vasoactive dinucleotide possessing natriuretic activity. It is unclear, however, which part of the nephron is the target site of action for Ap4A. Methods: We evaluated the tubular sites of
Autor:
Ewelina Kreft, Agnieszka Piwkowska, Dorota Rogacka, Maciej Jankowski, Irena Audzeyenka, Malgorzata Kasztan, Miroslawa Szczepanska-Konkel
Publikováno v:
American journal of physiology. Renal physiology. 311(1)
Purinoceptors (adrengeric receptors and P2 receptors) are expressed on the cellular components of the glomerular filtration barrier, and their activation may affect glomerular permeability to albumin, which may ultimately lead to albuminuria, a well-
Publikováno v:
Experimental Cell Research. 286:152-163
The activity of adenosine kinase (AK) was significantly impaired in splenocytes isolated from diabetic rats. Administration of insulin to diabetic animals restored AK activity, protein, and mRNA levels in diabetic splenocytes. Experiments performed o
Autor:
Agnieszka Ćwiklińska, Ewa Król, Ewa Wieczorek, Robert Kowalski, Kamil Dabkowski, Miroslawa Szczepanska-Konkel, Anna Gliwińska, Barbara Kortas-Stempak, Maciej M. Jankowski, Monika Cackowska, Agnieszka Kuchta
Publikováno v:
Atherosclerosis. 263:e272
Publikováno v:
British Journal of Pharmacology. 121:635-642
The aim of the study was to investigate whether cicletanine (CIC), as a potential inhibitor of cyclic GMP phosphodiesterase, is able to restore glomerular response to atrial natriuretic factor (ANF) in rats under conditions of diet deprived of sodium