Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Miroslava, Vosahlikova"'
Autor:
Hana Ujcikova, Kristina Cechova, Michal Jagr, Lenka Roubalova, Miroslava Vosahlikova, Petr Svoboda
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231721 (2020)
Opioid addiction is recognized as a chronic relapsing brain disease resulting from repeated exposure to opioid drugs. Cellular and molecular mechanisms underlying the ability of organism to return back to the physiological norm after cessation of dru
Externí odkaz:
https://doaj.org/article/1d66f37a229843e996750502c0ab8910
Autor:
Jonas Kaufman, Lenka Roubalova, Jiřina Slaninová, Martin Alda, Miroslava Vosahlikova, Petr Svoboda
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 394:955-965
Lithium (Li) represents a first choice mood stabilizer for bipolar disorder (BD). Despite extensive clinical use, questions regarding its mechanism of action and pathological mechanism of renal function impairment by Li remain open. The present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b7f1388d3ec2023e4d3b9158756a213
https://doi.org/10.1007/s00210-020-02036-4
https://doi.org/10.1007/s00210-020-02036-4
Autor:
Lenka Roubalova, Miroslava Vosahlikova, Jana Brejchova, Jan Sykora, Vladimir Rudajev, Petr Svoboda
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135664 (2015)
HEK293 cells stably expressing PTX-insensitive δ-opioid receptor-Gi1α (C351I) fusion protein were homogenized, treated with low concentrations of non-ionic detergent Brij-58 at 0°C and fractionated by flotation in sucrose density gradient. In opti
Externí odkaz:
https://doaj.org/article/3a23d0cc122340e9900855eebd1b7165
Autor:
Miroslava Vosahlikova, Hana Ujcikova, Lenka Roubalova, Stanislav Musil, Martina Hlouskova, Martin Alda, Petr Svoboda
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 392:785-799
Regulation of Na+/K+-ATPase in bipolar disorder and lithium therapy has been investigated for more than 40 years. Contradictory results in this area may be caused by the difference between acute and long-term Li effects on cell metabolism and varianc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508532acddd8bba96b8b2f8cd53565d3
https://doi.org/10.1007/s00210-019-01631-4
https://doi.org/10.1007/s00210-019-01631-4
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(9)
Lithium is regarded as a unique therapeutic agent for the management of bipolar disorder (BD). In efforts to explain the favourable effects of lithium in BD, a wide range of mechanisms was suggested. Among those, the effect of clinically relevant con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be88d0370a040b9a5dcea103601fde8
https://pubmed.ncbi.nlm.nih.gov/33991653
https://pubmed.ncbi.nlm.nih.gov/33991653
Autor:
Martina Hlouskova, Stanislav Musil, Miroslava Vosahlikova, Lenka Roubalova, Hana Ujcikova, Martin Alda, Petr Svoboda
Publikováno v:
Biochemical Pharmacology. 154:452-463
The functional state of δ-opioid receptor signaling cascade in live cells exposed to a therapeutic concentration of lithium for a prolonged period of time (weeks) is not known because the previous studies of Li interference with OR were oriented to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd34008c3d185642c5bce82de827cc7
https://doi.org/10.1016/j.bcp.2018.06.004
https://doi.org/10.1016/j.bcp.2018.06.004
Autor:
Lenka Roubalova, Martin Alda, Oleksandr Chernyavskiy, Hana Ujcikova, Miroslava Vosahlikova, Petr Svoboda, Jana Brejchova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:1099-1112
Background The effect of long-term exposure of live cells to lithium cations (Li) was studied in HEK293 cells cultivated in the presence of 1 mM LiCl for 7 or 21 days. The alteration of Na+/K+-ATPase level, protein composition and biophysical state o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c20f773a3b35eeac156e67708e1806c
https://doi.org/10.1016/j.bbagen.2017.02.011
https://doi.org/10.1016/j.bbagen.2017.02.011
Autor:
Kristina Cechova, Petr Svoboda, Hana Ujcikova, Miroslava Vosahlikova, Michal Jágr, Lenka Roubalova
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231721 (2020)
PLoS ONE
PLoS ONE
Opioid addiction is recognized as a chronic relapsing brain disease resulting from repeated exposure to opioid drugs. Cellular and molecular mechanisms underlying the ability of organism to return back to the physiological norm after cessation of dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4c4e0a21267c144797696abc318f54
https://doaj.org/article/1d66f37a229843e996750502c0ab8910
https://doaj.org/article/1d66f37a229843e996750502c0ab8910
Autor:
Miroslava, Vosahlikova, Lenka, Roubalova, Kristina, Cechova, Jonas, Kaufman, Stanislav, Musil, Ivan, Miksik, Martin, Alda, Petr, Svoboda
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 102
Lithium (Li) is a typical mood stabilizer and the first choice for treatment of bipolar disorder (BD). Despite an extensive clinical use of Li, its mechanisms of action remain widely different and debated. In this work, we studied the time-course of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90eb2e4c2f456d781c7adc6ee8e9d13b
https://pubmed.ncbi.nlm.nih.gov/32360816
https://pubmed.ncbi.nlm.nih.gov/32360816
Autor:
Miroslava Vosahlikova, Šárka Pokorná, Martin Hof, Piotr Jurkiewicz, Jan Sýkora, Lukasz Cwiklik, Petr Svoboda, Adéla Melcrová
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 35(35)
Regulation of cell metabolism, membrane fusion, association of proteins with cellular membranes, and cellular signaling altogether would not be possible without Ca2+ ions. The distribution of calcium within the cell is uneven with the negatively char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ad69bd8d8bf31838f21b79a7e8c544
https://pubmed.ncbi.nlm.nih.gov/31393734
https://pubmed.ncbi.nlm.nih.gov/31393734