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Neurobehavioural changes in rats after neonatal anoxia: effect of antioxidant stobadine pretreatment
Autor:
Eduard, Ujházy, Miroslava, Schmidtová, Michal, Dubovický, Jana, Navarova, Ingrid, Brucknerová, Mojmír, Mach
Publikováno v:
Neuro endocrinology letters. 27
The aim of this study was to evaluate the effect of the synthetic pyridoindole antioxidant stobadine (STO, 50mg/kg/day) on behavioural alterations induced by acute neonatal anoxia in rat offspring.STO was administered orally from day 15 of gestation
Publikováno v:
Neuro endocrinology letters. 27
To assess the time course of biochemical responses to neonatal anoxia.Neonatal anoxia was induced by placing 2-day-old rat pups into a glass chamber with 100% N(2) atmosphere, T=36.5 degrees C, for 20 minutes. The samples of serum, brain, lungs and l