Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Miroslava, Didiasova"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Enolase is a glycolytic enzyme, which catalyzes the inter-conversion of 2-phosphoglycerate to phosphoenolpyruvate. Altered expression of this enzyme is frequently observed in cancer and accounts for the Warburg effect, an adaptive response of tumor c
Externí odkaz:
https://doaj.org/article/3f3c5ec6461e422bb34602aa531856af
Autor:
Miroslava Didiasova, Antje Banning, Heiko Brennenstuhl, Sabine Jung-Klawitter, Claudio Cinquemani, Thomas Opladen, Ritva Tikkanen
Publikováno v:
Cells, Vol 9, Iss 2, p 477 (2020)
Succinic semialdehyde dehydrogenase deficiency (SSADH-D) is a genetic disorder that results from the aberrant metabolism of the neurotransmitter γ-amino butyric acid (GABA). The disease is caused by impaired activity of the mitochondrial enzyme succ
Externí odkaz:
https://doaj.org/article/2fe4b8fc534446b4beecf75e55f07846
Publikováno v:
Molecules, Vol 23, Iss 5, p 1003 (2018)
Aberrant activation of hedgehog (Hh) signaling has been observed in a wide variety of tumors and accounts for more than 25% of human cancer deaths. Inhibitors targeting the Hh signal transducer Smoothened (SMO) are widely used and display a good init
Externí odkaz:
https://doaj.org/article/c70ebae2295f489c802ce6059e0fea17
Autor:
Anna Gungl, Miroslava Didiasova, Djuro Kosanovic, Walter Klepetko, Ralph T. Schermuly, Aleksandar Petrovic, Grazyna Kwapiszewska, Malgorzata Wygrecka, Marius M. Zucker, Lukasz Wujak, Liliana Schaefer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1604-1616
Pulmonary hypertension (PH) is characterized by a thickening of the distal pulmonary arteries caused by medial hypertrophy, intimal proliferation and vascular fibrosis. Low density lipoprotein receptor-related protein 1 (LRP1) maintains vascular home
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ff4131305d5018da63f708c6ca5836
https://doi.org/10.1016/j.bbadis.2019.03.012
https://doi.org/10.1016/j.bbadis.2019.03.012
Autor:
Heiko, Brennenstuhl, Miroslava, Didiasova, Birgit, Assmann, Mariarita, Bertoldi, Gianluca, Molla, Sabine, Jung-Klawitter, Oya, Kuseyri Hübschmann, Julian, Schröter, Thomas, Opladen, Ritva, Tikkanen
Publikováno v:
International Journal of Molecular Sciences
Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare, monogenic disorder affecting the degradation of the main inhibitory neurotransmitter γ-amino butyric acid (GABA). Pathogenic variants in the ALDH5A1 gene that cause an enzymatic dysf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0fe64b90af976995ab17286583623f6
https://pubmed.ncbi.nlm.nih.gov/33203024
https://pubmed.ncbi.nlm.nih.gov/33203024
Autor:
Antje Banning, Heiko Brennenstuhl, Claudio Cinquemani, Thomas Opladen, Sabine Jung-Klawitter, Miroslava Didiasova, Ritva Tikkanen
Publikováno v:
Cells, Vol 9, Iss 2, p 477 (2020)
Cells
Cells
Succinic semialdehyde dehydrogenase deficiency (SSADH-D) is a genetic disorder that results from the aberrant metabolism of the neurotransmitter γ-amino butyric acid (GABA). The disease is caused by the impaired activity of the mitochondrial enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66352d070c957f13a728e18975b6d506
https://www.mdpi.com/2073-4409/9/2/477
https://www.mdpi.com/2073-4409/9/2/477
Autor:
Nelli Baal, Ingrid Henneke, Grazyna Kwapiszewska, Leigh M. Marsh, Holger Hackstein, Dariusz Zakrzewicz, Marc W. Nolte, de Maat S, Martin Witzenrath, Malgorzata Wygrecka, Ralph T. Schermuly, Werner Seeger, Con Panousis, P. Markart, Lukasz Wujak, Katrin Reppe, Djuro Kosanovic, Miroslava Didiasova, Holger Müller-Redetzky, Helena Frey, Liliana Schaefer, Coen Maas
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 196:186-199
Acute respiratory distress syndrome is characterized by alveolar epithelial cell injury, edema formation, and intraalveolar contact phase activation.To explore whether C1 esterase inhibitor (C1INH), an endogenous inhibitor of the contact phase, may p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1f046f676262dfd92b1ed360955c85
https://doi.org/10.1164/rccm.201604-0712oc
https://doi.org/10.1164/rccm.201604-0712oc
Autor:
Malgorzata Wygrecka, Matthias Lauth, Dariusz Zakrzewicz, Philipp Markart, Liliana Schaefer, Miroslava Didiasova, Jochen Wilhelm, Werner Seeger, Lukasz Wujak, Rajeev Singh, Grazyna Kwapiszewska
Publikováno v:
The FASEB Journal. 31:1916-1928
Pirfenidone is an antifibrotic drug, recently approved for the treatment of patients with idiopathic pulmonary fibrosis (IPF). Although pirfenidone exhibits anti-inflammatory, antioxidant, and antifibrotic properties, the molecular mechanism underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1213789d7b5cf6f6126fd5abebdb26
https://doi.org/10.1096/fj.201600892rr
https://doi.org/10.1096/fj.201600892rr
Autor:
Grazyna Kwapiszewska, Anna Gungl, Jochen Wilhelm, Leigh M. Marsh, Helene Thekkekara Puthenparampil, Katharina Sinn, Miroslava Didiasova, Walter Klepetko, Djuro Kosanovic, Ralph T. Schermuly, Lukasz Wujak, Benjamin Weiss, Liliana Schaefer, Marc Schneider, Michael Kreuter, Andrea Olschewski, Werner Seeger, Horst Olschewski, Malgorzata Wygrecka
Publikováno v:
Idiopathic interstitial pneumonias.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bc6f751732ad5296f5085be03584e6
https://doi.org/10.1183/13993003.congress-2019.pa1280
https://doi.org/10.1183/13993003.congress-2019.pa1280
Autor:
Matthias Krämer, Argen Mamazhakypov, Malgorzata Wygrecka, Liliana Schaefer, Miroslava Didiasova, Fotis Drakopanagiotakis, Philipp Markart
Publikováno v:
Cellular signalling. 65
Pirfenidone (PFD) is an orally available synthetic drug which has been approved for the treatment of idiopathic pulmonary fibrosis. In addition to its anti-fibrotic properties, PFD also exerts anti-tumor effects in cancer models by inducing alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0945a9dec1d98f1af2dee762a04939ba
https://pubmed.ncbi.nlm.nih.gov/31693876
https://pubmed.ncbi.nlm.nih.gov/31693876