Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Miroslav Terinek"'
Publikováno v:
The Journal of organic chemistry. 80(23)
An asymmetric total synthesis of the nootropic alkaloid (-)-huperzine A was completed using a cascade sequence initiated by an intramolecular aza-Prins reaction and terminated by a stereoelectronically guided fragmentation of a cyclobutylcarbinyl cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c008c72d8c2a9c7db03361e58d331c6
https://pubmed.ncbi.nlm.nih.gov/26355759
https://pubmed.ncbi.nlm.nih.gov/26355759
Autor:
Miroslav Terinek, Andrea Vasella
Publikováno v:
Helvetica Chimica Acta. 88:10-22
The gluco-configured analogue 15 of nagstatin (1) and the methyl ester 14 were synthesized via condensation of the thionolactams 17 or 18 with the β-amino ester 19. The silyl ethers 20 and 21 resulting from 17 were desilylated to 22 and 23; these al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f8526420585f6d6fb893ed3b567937
https://doi.org/10.1002/hlca.200490286
https://doi.org/10.1002/hlca.200490286
Autor:
Miroslav Terinek, Andrea Vasella
Publikováno v:
Tetrahedron: Asymmetry. 16:449-469
The inhibition of snail β-mannosidase by the manno-configured amino- and hydroxy-lactams and -imidazoles 7–10 was compared to the inhibition of the β-glucosidases from Caldocellum saccharolyticum and from sweet almonds by the gluco-configured ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1997baec6fd5f9a83ac0888f806ad7
https://doi.org/10.1016/j.tetasy.2004.11.068
https://doi.org/10.1016/j.tetasy.2004.11.068
Autor:
Andrea Vasella, Miroslav Terinek
Publikováno v:
Helvetica Chimica Acta. 87:3035-3049
The gluco- and manno-tetrahydropyridoimidazole-2-acetates and -acetic acids 16 and 17, and 20 and 21, respectively, were synthesized by condensation, in the presence of HgCl2, of the known thionolactam 26 with the β-amino ester 25 that was obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347b6d0cd3bfa77a50ec537536257ed8
https://doi.org/10.1002/hlca.200490273
https://doi.org/10.1002/hlca.200490273
Autor:
Andrea Vasella, Miroslav Terinek
Publikováno v:
Helvetica Chimica Acta. 86:3482-3509
It was shown that retaining β-glucosidases and galactosidases of families 1–3 feature a strong interaction between C(2)OH of the substrate and the catalytic nucleophile. An analogous interaction can hardly take place for retaining β-mannosidases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09f0cce1165cf54d1f4acdc3ef95ecde
https://doi.org/10.1002/hlca.200390293
https://doi.org/10.1002/hlca.200390293
Publikováno v:
Collection of Czechoslovak Chemical Communications. 62:1325-1341
Four optically pure isomers of methyl 11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate (1a-1d) were synthesized using an approach reverse to the classical Corey procedure, the key intermediates being the easily accessible (-)- and (+)-enantiomers of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cba4e916b143fc4133359e6b3f8b6061
https://doi.org/10.1135/cccc19971325
https://doi.org/10.1135/cccc19971325
Publikováno v:
Organic letters. 15(4)
The acetylcholinesterase inhibitor (-)-huperzine A was synthesized from (S)-4-hydroxycyclohex-2-enone in 17 steps by a route that involved two cyclobutane fragmentations. The first of these employed a retro-aldol cleavage to generate the α-pyridone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8927256f8d44d2cc545558064d59732
https://pubmed.ncbi.nlm.nih.gov/23346936
https://pubmed.ncbi.nlm.nih.gov/23346936
Publikováno v:
ChemInform. 28
Four optically pure isomers of methyl 11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate (1a-1d) were synthesized using an approach reverse to the classical Corey procedure, the key intermediates being the easily accessible (-)- and (+)-enantiomers of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e08dead60161c3e28e18ed7d14379e
https://doi.org/10.1002/chin.199751266
https://doi.org/10.1002/chin.199751266
Autor:
Andrea Vasella, Miroslav Terinek
Publikováno v:
ChemInform. 35
The D-manno-tetrahydroimidazopyridine-2-phosphonate 11 was prepared via a high-yielding Pd(PPh3)(4)-catalysed diphenylphosphonylation of the manno-iodoimidazole 12, followed by transesterification to the diethyl phosphonate 14 and dealkylation, provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150b7634c3e9775dc3059a90a479884d
https://doi.org/10.1002/chin.200432205
https://doi.org/10.1002/chin.200432205
Autor:
Andrea Vasella, Miroslav Terinek
Publikováno v:
XXIst International Carbohydrate Symposium 2002.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60453591cb15d3b3463191fd66ef92bb
https://doi.org/10.1100/tsw.2002.643
https://doi.org/10.1100/tsw.2002.643