Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Miroslav Sisa"'
Publikováno v:
Molecules, Vol 15, Iss 8, Pp 5196-5245 (2010)
Flavonoids and their photochemical transformations play an important role in biological processes in nature. Synthetic photochemistry allows access to molecules that cannot be obtained via more conventional methods. This review covers all published s
Externí odkaz:
https://doaj.org/article/35b6e2670aef4bd7be6e1ffc472d498d
Autor:
Miroslav Sisa, Lukáš Konečný, Veronika Temml, Alejandro Carazo, Přemysl Mladěnka, Přemysl Landa
Publikováno v:
Archiv der Pharmazie. 356
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24b9106e93fd18abf7fee6d77ca14214
https://doi.org/10.1002/ardp.202200549
https://doi.org/10.1002/ardp.202200549
Autor:
Galyna Bila, Andriy Mokhir, Hong-Gui Xu, Wenjie Gong, Miroslav Sisa, Rostyslav Bilyy, Steffen Daum, Insa Klemt, Michael Schmitt, Margot Schikora, Leopold Sellner, Christoph Alexiou, Christina Janko
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition
The folding and export of proteins and hydrolysis of unfolded proteins are disbalanced in the endoplasmic reticulum (ER) of cancer cells, leading to so‐called ER stress. Agents further augmenting this effect are used as anticancer drugs including c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ade35816b81431eeecde371982b3d3
https://opus4.kobv.de/opus4-fau/files/16609/ANIE_ANIE202100054.pdf
https://opus4.kobv.de/opus4-fau/files/16609/ANIE_ANIE202100054.pdf
Autor:
Veronika Temml, Veronika Jarosova, Miroslav Sisa, Premysl Landa, Marcela Dvorakova, Tomas Vanek
Publikováno v:
European journal of medicinal chemistry. 204
Based on the significant anti-inflammatory activity of natural quinone primin (5a), series of 1,4-benzoquinones, hydroquinones, and related resorcinols were designed, synthesized, characterized and tested for their ability to inhibit the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c05d275b980234b6cbbca5f079c22eb
https://pubmed.ncbi.nlm.nih.gov/32738413
https://pubmed.ncbi.nlm.nih.gov/32738413
Publikováno v:
Chemical Engineering Journal. 421:127783
Climbazole (CBZ) and fluconazole (FCZ) belong to the class of azole antifungal drugs that are widely used in medicine and as ingredients of cosmetics, and in result have been frequently detected in municipal and domestic wastewater and in natural wat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a79e79dc19986616610b5733ba72408
https://doi.org/10.1016/j.cej.2020.127783
https://doi.org/10.1016/j.cej.2020.127783
Autor:
Christina Janko, Maxim D. Lootsik, Tetyana Dumych, Christoph Alexiou, Andriy Mokhir, Leopold Sellner, Rostyslav Bilyy, Miroslav Sisa, Martin Herrmann, Evgenia Bila, Steffen Daum, M. S. Viktor Reshetnikov
Publikováno v:
Angewandte Chemie. 129:15751-15755
Cancer cells produce elevated levels of reactive oxygen species, which has been used to design cancer specific prodrugs. Their activation relies on at least a bimolecular process, in which a prodrug reacts with ROS. However, at low micromolar concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe9d1e344a256830a27b66482007a07
https://doi.org/10.1002/ange.201706585
https://doi.org/10.1002/ange.201706585
Publikováno v:
Tetrahedron. 73:5297-5301
An efficient and short synthetic procedures affording the biologically active natural products primin, miconidin, olivetol, grevillol, and cardol (adipostatin A) in high yields are reported. The two strategies involve Sonogashira and Suzuki cross-cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac1cd915089a7c7a064aa2bd3e98500
https://doi.org/10.1016/j.tet.2017.07.029
https://doi.org/10.1016/j.tet.2017.07.029
Autor:
Miroslav Sisa, Tomas Vanek
Publikováno v:
Current Pharmaceutical Design. 22:1767-1807
This review covers the chemical reactions, synthesis, and biological activities of tetracyclic diterpenoids including ent-kauranes, ent-beyeranes, ent-atisanes, ingenanes, tyglianes, stemodanes, stemaranes, sordarin, salvileucalin B, harringtonolide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbae050c8aa11aa183bf16d4d88ab0d
https://doi.org/10.2174/1381612822666160105112218
https://doi.org/10.2174/1381612822666160105112218
Autor:
Mirela-Corina Codreanu, Jiří Friml, Miroslav Strnad, Annemieke Madder, Daniël Van Damme, Anna-Mária Szatmári, Dieter Buyst, Evelien Mylle, Joanna Schneider-Pizoń, Ana I. Caño-Delgado, Ladislav Kohout, Simone Di Rubbo, Jaroslava Hniliková, Jos Van den Begin, Miroslav Sisa, Niloufer G. Irani, Eugenia Russinova, Josep Vilarrasa-Blasi, Kiril Mishev
Publikováno v:
Nature Chemical Biology. 8:583-589
Receptor-mediated endocytosis is an integral part of signal transduction as it mediates signal attenuation and provides spatial and temporal dimensions to signaling events. One of the best-studied leucine-rich repeat receptor-like kinases in plants,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ca8fdee8f18ce25b0e4d96056f68c3
https://doi.org/10.1038/nchembio.958
https://doi.org/10.1038/nchembio.958
Publikováno v:
Molecules
Molecules, Vol 15, Iss 8, Pp 5196-5245 (2010)
Molecules, Vol 15, Iss 8, Pp 5196-5245 (2010)
Flavonoids and their photochemical transformations play an important role in biological processes in nature. Synthetic photochemistry allows access to molecules that cannot be obtained via more conventional methods. This review covers all published s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f00e0bfc21e590f2863c4c9bf0b82a
https://doi.org/10.3390/molecules15085196
https://doi.org/10.3390/molecules15085196