Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Miroslav Penka"'
Autor:
Inge Vangenechten, Petr Smejkal, Jiri Zavrelova, Ondrej Zapletal, Alexander Wild, Jan Jacques Michiels, Zwi Berneman, Jan Blatny, Angelika Batorova, Tatiana Prigancova, Miroslav Penka, Alain Gadisseur
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e335-e346 (2022)
Background von Willebrand disease (VWD) is a genetic bleeding disorder caused by defects of von Willebrand factor (VWF), quantitative (type 1 and 3) or qualitative (type 2). The laboratory phenotyping is heterogenic making diagnosis difficult. Object
Externí odkaz:
https://doaj.org/article/75dd3755ee8443b3a845469109e1de0d
Autor:
Lenka Besse, Lenka Sedlarikova, Fedor Kryukov, Jana Nekvindova, Lenka Radova, Ondrej Slaby, Petr Kuglik, Martina Almasi, Miroslav Penka, Marta Krejci, Zdenek Adam, Ludek Pour, Sabina Sevcikova, Roman Hajek
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137294 (2015)
Poor outcome of extramedullary disease in multiple myeloma patients and lack of outcome predictors prompt continued search for new markers of the disease. In this report, we show circulating microRNA distinguishing multiple myeloma patients with extr
Externí odkaz:
https://doaj.org/article/1c18f8435a574f45a2322070f78e88ad
Autor:
Karthick Raja Muthu Raja, Lucie Rihova, Lenka Zahradova, Maria Klincova, Miroslav Penka, Roman Hajek
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47077 (2012)
BACKGROUND: Regulatory T (Treg) cells play an important role in the maintenance of immune system homeostasis. Multiple myeloma (MM) is a plasma cell disorder frequently associated with impaired immune cell numbers and functions. METHODS: We analyzed
Externí odkaz:
https://doaj.org/article/8cf8adbe7bbc4b2991ac3f9babec0bc9
Autor:
Alena Buliková, Miroslav Penka
Publikováno v:
Vnitrni lekarstvi. 68(8)
Antiphosholipid syndrome (APS) is defined by the presence of clinical and laboratory criteria, it means by presence of antiphospholipid antibodies. Venous thromboembolism belongs to the most frequent clinical manifestation of this syndrome. Here we s
Autor:
Tomas Jelinek, Renata Bezdekova, David Zihala, Tereza Sevcikova, Anjana Anilkumar Sithara, Lenka Pospisilova, Sabina Sevcikova, Petra Polackova, Martin Stork, Zdenka Knechtova, Ondrej Venglar, Veronika Kapustova, Tereza Popkova, Ludmila Muronova, Zuzana Chyra, Matous Hrdinka, Michal Simicek, Juan-Jose Garcés, Noemi Puig, Maria-Teresa Cedena, Artur Jurczyszyn, Jorge J. Castillo, Miroslav Penka, Jakub Radocha, Maria Victoria Mateos, Jesús F. San-Miguel, Bruno Paiva, Ludek Pour, Lucie Rihova, Roman Hajek
Publikováno v:
Journal of clinical oncology
PURPOSE Primary plasma cell leukemia (PCL) is the most aggressive monoclonal gammopathy. It was formerly characterized by ≥ 20% circulating plasma cells (CTCs) until 2021, when this threshold was decreased to ≥ 5%. We hypothesized that primary PC
Publikováno v:
Vnitřní lékařství. 67:175-179
Pembrolizumab belongs to so called immune checkpoint inhibitors. Frequent adverse event of this therapy is hypothyroidism. The authors present a case report of patient treated with pembrolizumab for non-small cell lung carcinoma, in whom severe hypot
Autor:
Antonin Hlusi, Ester Zápotocká, Petr Smejkal, Jan Blatný, R. Hrdličková, Miroslav Penka, Zdeňka Hajšmanová
Publikováno v:
Transfuze a hematologie dnes. 27:73-90
Publikováno v:
Neoplasma. 68:1341-1350
Thrombosis is the most common complication in BCR-ABL1 negative myeloproliferative neoplasms (MPN) that significantly impacts patients' mortality. Generally, there is an agreement on risk factors that possibly contribute to the increased risk of thro
Autor:
Jan Novotný, Miroslav Penka
Publikováno v:
Intervenční a akutní kardiologie. 19:215-221
Po cestě za idealnim antitrombotikem s terapeutickou ucinnosti při dobrem bezpecnostnim profilu s možnosti parenteralniho podavani, rychlým nastupem ucinku, bez nutnosti rutinni laboratorni kontroly, minimem lekových a potravinových interakci a
Autor:
Jana Lindušková, Markéta Šejnohová, Michael Doubek, Leoš Křen, Miroslav Penka, Pavel Polák, Andrea Pavlíková
Publikováno v:
Vnitřní lékařství. 67:E26-E28
Autoři předkladaji kazuistiku 59lete ženy dosetřovane pro recentně zjistěnou pancytopenii během hospitalizace pro oboustrannou intersticialni pneumonii bez zjistěneho vyvolavajiciho agens. Soucasně byly přitomny systemove symptomy nechutens