Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Miroslav N, Nenov"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Growing body of evidence suggests that cardiovascular risk factor, asymmetric dimethylarginine (ADMA), can be implicated in the pathogenesis of neurodegenerative and psychiatric disorders. In part, ADMA can affect brain health negatively modulating c
Externí odkaz:
https://doaj.org/article/6488eb7dd62f442ba1eb330f2268327d
Autor:
Melissa C. Knouse, Andre U. Deutschmann, Miroslav N. Nenov, Mathieu E. Wimmer, Lisa A. Briand
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Glutamate signaling within the nucleus accumbens underlies motivated behavior and is involved in psychiatric disease. Although behavioral sex differences in these processes are well-established, the neural mechanisms driving these
Externí odkaz:
https://doaj.org/article/b34a4c012d1f428cb0cf682f82d382fb
Autor:
Alexey S. Averin, Maxim V. Konakov, Oleg Y. Pimenov, Miliausha H. Galimova, Alexey V. Berezhnov, Miroslav N. Nenov, Vladimir V. Dynnik
Publikováno v:
Membranes, Vol 12, Iss 12, p 1239 (2022)
Various models, including stem cells derived and isolated cardiomyocytes with overexpressed channels, are utilized to analyze the functional interplay of diverse ion currents involved in cardiac automaticity and excitation–contraction coupling cont
Externí odkaz:
https://doaj.org/article/33d8166891dc493cb7eb5da0664f995f
Autor:
Jessica Di Re, Wei-Chun J. Hsu, Cihan B. Kayasandik, Nickolas Fularczyk, T. F. James, Miroslav N. Nenov, Pooran Negi, Mate Marosi, Federico Scala, Saurabh Prasad, Demetrio Labate, Fernanda Laezza
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
The axon initial segment (AIS) is a highly regulated subcellular domain required for neuronal firing. Changes in the AIS protein composition and distribution are a form of structural plasticity, which powerfully regulates neuronal activity and may un
Externí odkaz:
https://doaj.org/article/c2065099e1604f758c3ff8744faa037f
Autor:
Mate Marosi, Miroslav N. Nenov, Jessica Di Re, Nolan M. Dvorak, Musaad Alshammari, Fernanda Laezza
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1700 (2022)
In neurons, changes in Akt activity have been detected in response to the stimulation of transmembrane receptors. However, the mechanisms that lead to changes in neuronal function upon Akt inhibition are still poorly understood. In the present study,
Externí odkaz:
https://doaj.org/article/dcae7ba5c4754ba8a087ea6a402a38b8
Publikováno v:
Toxins, Vol 14, Iss 2, p 88 (2022)
Cardiotoxins (CaTxs) are a group of snake toxins that affect the cardiovascular system (CVS). Two types (S and P) of CaTxs are known, but the exact differences in the effects of these types on CVS have not been thoroughly studied. We investigated cel
Externí odkaz:
https://doaj.org/article/b683c845f2344bb1a6bcad66c52a37df
Autor:
Federico Scala, Miroslav N. Nenov, Elizabeth J. Crofton, Aditya K. Singh, Oluwarotimi Folorunso, Yafang Zhang, Brent C. Chesson, Norelle C. Wildburger, Thomas F. James, Musaad A. Alshammari, Tahani K. Alshammari, Hannah Elfrink, Claudio Grassi, James M. Kasper, Ashley E. Smith, Jonathan D. Hommel, Cheryl F. Lichti, Jai S. Rudra, Marcello D’Ascenzo, Thomas A. Green, Fernanda Laezza
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 555-567 (2018)
Summary: Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na+ channel Nav1.6
Externí odkaz:
https://doaj.org/article/dc94cfdd1eef4764a9b23adba0a07db4
Autor:
Alexey V. Berezhnov, Evgeniya I. Fedotova, Miroslav N. Nenov, Vitaly A. Kasymov, Oleg Yu. Pimenov, Vladimir V. Dynnik
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7461 (2020)
Long-chain acylcarnitines (LCAC) are implicated in ischemia-reperfusion (I/R)-induced myocardial injury and mitochondrial dysfunction. Yet, molecular mechanisms underlying involvement of LCAC in cardiac injury are not sufficiently studied. It is know
Externí odkaz:
https://doaj.org/article/41a10dab52a247f3a062f5cdafc38877
Autor:
A. S. Averin, Svetlana S Popova, Leonid S Kosarsky, L. A. Andreeva, A. I. Anufriev, O. V. Nakipova, Miroslav N. Nenov
Publikováno v:
Journal of Comparative Physiology B. 191:927-939
The effect of phenylephrine (PE) on right ventricle papillary muscle (PM) and aortic segment (AS) contractile activity was studied in long-tailed ground squirrels Urocitellus undulatus during summer activity, torpor and interbout active (IBA) periods
Autor:
S. G. Gaidin, A. I. Sergeev, Valery P. Zinchenko, Artem M. Kosenkov, I. Yu. Teplov, Miroslav N. Nenov
Publikováno v:
Biochemical and Biophysical Research Communications. 553:99-106
Spontaneous burst firing is a hallmark attributed to the neuronal network activity. It is known to be accompanied by intracellular calcium [Са2+]i oscillations within the bursting neurons. Studying mechanisms underlying regulation of burst firing i