Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Miroslav J. Novak"'
Autor:
Miroslav J. Novak, Casey D. Morrow, Lesley E. Smythies, Ken B. Waites, J. Russell Lindsey, Phillip D. Smith
Publikováno v:
Vaccine. 23:901-909
We developed a novel vaccine for Helicobacter pylori based on a poliovirus vector in which capsid genes were replaced with the gene for the B subunit of H. pylori urease (UreB). Mice were vaccinated with UreB or control (L1) replicon and challenged w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b4a9046c3cfab9c0944ffaab34094e
https://doi.org/10.1016/j.vaccine.2004.07.037
https://doi.org/10.1016/j.vaccine.2004.07.037
Autor:
Miroslav J. Novak, Donna C. Porter, Patricia N. Fultz, Jackie Stallworth, Marie J. Anderson, Casey D. Morrow
Publikováno v:
Virology. 315:425-437
In the search for an effective vaccine against the human immunodeficiency virus (HIV), novel ways to deliver viral antigens are being evaluated. One such approach is the use of nonreplicating viral vectors encoding HIV and/or SIV genes that are expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531facb3338f9aba2f75e6e9b3c2c6d6
https://doi.org/10.1016/s0042-6822(03)00546-4
https://doi.org/10.1016/s0042-6822(03)00546-4
Autor:
Matthew T. Palmer, Wen Qiang Huang, Sylvia A. McPherson, Cheryl A. Jackson, Miroslav J. Novak, Casey D. Morrow, Zina Moldoveanu
Publikováno v:
Viral Immunology. 16:169-182
Vaccines that stimulate both cellular and humoral immunity will probably be needed to control many infectious diseases. Previously, our laboratory generated a vaccine vector that uses poliovirus genomes (replicons) in which the capsid genes have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd0eb0fc5708d7ff57952730e18ede8
https://doi.org/10.1089/088282403322017901
https://doi.org/10.1089/088282403322017901
Autor:
Mônica S. Freitas, Ana C. Silva, Luciane Pinto Gaspar, Miroslav J. Novak, Waleska Dias Schwarcz, Andre M. O. Gomes, Jiri Mestecky, Jerson L. Silva, Ana Paula Dinis Ano Bom, Debora Foguel
Publikováno v:
Journal of Biological Chemistry. 277:8433-8439
Enveloped animal viruses must undergo membrane fusion to deliver their genome into the host cell. We demonstrate that high pressure inactivates two membrane-enveloped viruses, influenza and Sindbis, by trapping the particles in a fusion-intermediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132e22eb3a84fb4b3755caa2d60d1848
https://doi.org/10.1074/jbc.m106096200
https://doi.org/10.1074/jbc.m106096200
Publikováno v:
Human Gene Therapy. 12:1827-1841
Poliovirus-based vectors (replicons) can be used for gene delivery to motor neurons of the CNS. In the current study, a replicon encoding green fluorescent protein (GFP) was encapsidated into authentic poliovirions, using established procedures. Intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fa30cc6967988a86450535196465f2
https://doi.org/10.1089/104303401753153893
https://doi.org/10.1089/104303401753153893
Autor:
Lesley E. Smythies, Sylvia A. McPherson, Casey D. Morrow, Miroslav J. Novak, Phillip D. Smith
Publikováno v:
Vaccine. 17:2384-2391
The development of a vaccine for Helicobacter pylori is a key strategy for reducing the worldwide prevalence of H. pylori infection. Although immunization with recombinant B subunit of H. pylori urease (ureB) has yielded promising results, for the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289af1f9c8d51b83eae44a9cd3de0837
https://doi.org/10.1016/s0264-410x(99)00035-3
https://doi.org/10.1016/s0264-410x(99)00035-3
Autor:
F W van Ginkel, Miroslav J. Novak, Jerry R. McGhee, Hiroshi Kiyono, Huan H. Nguyen, Jiri Mestecky, Zina Moldoveanu, E. M. Ban
Publikováno v:
Virology. 254:50-60
Heterosubtypic immunity, defined as cross-reactive immune responses to influenza virus of a different serotype than the virus initially encountered, was investigated in association with virus-specific cytotoxic T lymphocyte (CTL) responses induced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a01bd763921a3b1e3fa323a8749dc7
https://doi.org/10.1006/viro.1998.9521
https://doi.org/10.1006/viro.1998.9521
Autor:
Pei Xuan Wang, Richard W. Compans, Jiri Mestecky, Jacqueline D. Duncan, Dennis P. Schafer, Catherine M. Harrington, Yumiko Matsuoka, Miroslav J. Novak
Publikováno v:
Journal of Controlled Release. 41:237-247
In this paper a comparison of delivery systems for a live rotavirus vaccine is presented. The loss of infectivity was estimated during incorporation into the delivery systems, and during the subsequent processing steps in the preparation of poly( dl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f2b359e6524016b405b76d3c2ef0023
https://doi.org/10.1016/0168-3659(96)01331-4
https://doi.org/10.1016/0168-3659(96)01331-4
Autor:
Richard W. Compans, Wen-Qiang Huang, Richard M. Gilley, Dennis P. Schafer, Jay K. Staas, Miroslav J. Novak, Zina Moldoveanu, Jiri Mestecky
Publikováno v:
Journal of Controlled Release. 28:131-141
Mucosal membranes are the most frequent portals of entry of almost all infectious agents. The most important protective humoral factors on mucosal surfaces are locally produced antibodies predominantly of the IgA isotype. Therefore, the induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96cc63e09131ed3b9d4b247d51f798f6
https://doi.org/10.1016/0168-3659(94)90160-0
https://doi.org/10.1016/0168-3659(94)90160-0
Autor:
Dennis P. Schafer, Richard M. Gilley, Richard W. Compans, Jay K. Staas, Wen-Qiang Huang, Zina Moldoveanu, Jiri Mestecky, Miroslav J. Novak
Publikováno v:
Journal of Infectious Diseases. 167:84-90
Polymeric microspheres were evaluated as an oral antigen delivery system for immunization with influenza virus. The immune responses obtained were compared after either oral or systemic immunization of BALB/c mice using purified, formalin-inactivated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3373063f6447c7652684f2add6fad9f
https://doi.org/10.1093/infdis/167.1.84
https://doi.org/10.1093/infdis/167.1.84