Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Miroslav Huličiak"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1859:2113-2122
The Na+/K+-ATPase plays a key role in ion transport across the plasma membrane of all animal cells. The voltage-sensitive styrylpyrimidium dye RH421 has been used in several laboratories for monitoring of Na+/K+-ATPase kinetics. It is known, that RH4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79e7c80379adadcd1b099f8ca8665f11
https://doi.org/10.1016/j.bbamem.2017.07.016
https://doi.org/10.1016/j.bbamem.2017.07.016
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1859(10)
The Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29118d374c7e0bab99b6a7ec95b929d5
https://pubmed.ncbi.nlm.nih.gov/28774819
https://pubmed.ncbi.nlm.nih.gov/28774819
Autor:
Miroslav Huličiak, Martin Kubala, Joanna Znaleziona, Jan Vacek, Marika Havlikova, Marek Šebela, Eva Orolinová
Publikováno v:
Biochemical Pharmacology. 83:1507-1513
This study was aimed at verifying the hypothesis that acute kidney failure accompanying cisplatin administration in the cancer therapy could be due to cisplatin interaction with the cytoplasmic part of Na + /K + -ATPase. Our results demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5015b538554ccc5e79fa71e6d5cd30
https://doi.org/10.1016/j.bcp.2012.02.015
https://doi.org/10.1016/j.bcp.2012.02.015
Autor:
Miroslav Huličiak, Martin Kubala, Poul Nissen, Mette Laursen, Natalya U. Fedosova, Linda Reinhard
Publikováno v:
Huliciak, M, Reinhard, L, Laursen, M, Fedosova, N, Nissen, P & Kubala, M 2014, ' Crystals of Na(+)/K(+)-ATPase with bound cisplatin ', Biochemical Pharmacology, vol. 92, no. 3, pp. 494-498 . https://doi.org/10.1016/j.bcp.2014.08.029
Biochemical Pharmacology
Biochemical Pharmacology
Cisplatin is the most widely used chemotherapeutics for cancer treatment, however, its administration is connected to inevitable adverse effects. Previous studies suggested that cisplatin is able to inhibit Na(+)/K(+)-ATPase (NKA), the enzyme respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0a93fd86a7fcd6ce5d4ce3eafac211
https://pure.au.dk/portal/da/publications/crystals-of-nakatpase-with-bound-cisplatin(3e1e2e83-b0cf-4b68-ab8f-17045b6ea90f).html
https://pure.au.dk/portal/da/publications/crystals-of-nakatpase-with-bound-cisplatin(3e1e2e83-b0cf-4b68-ab8f-17045b6ea90f).html
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):568-576
Combination of fluorescence techniques and molecular docking was used to monitor interaction of Na,K-ATPase and its large cytoplasmic loop connecting fourth and fifth transmembrane helices (C45) with fluorone dyes (i.e. eosin Y, 5(6)-carboxyeosin, ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d67f4baca3d4b12b019aeedde4b8f5f