Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Miroslav Dostálek"'
Autor:
Miroslav Dostálek, Jana Benešová
Publikováno v:
Acta Medica, Vol 45, Iss 4, Pp 161-166 (2002)
The aim of the study was to evaluate the keystone role of paediatric general practitioners (PGPs) in our system of photoscreening of amblyogenic factors at children younger one year. The parental involvement on the participation of their children at
Externí odkaz:
https://doaj.org/article/50d92a8c435c4dd1a8c5a918357d6a8c
Autor:
Vladimír Liška, Miroslav Dostálek
Publikováno v:
Acta Medica, Vol 42, Iss 4, Pp 133-138 (1999)
Purpose: To confirm the influence of multilevel metabolic disturbance of insulin dependent diabetes mellitus (IDDM) on the vision even before the onset of the other changes routinely evaluated by ophthalmologists. Methods: Contrast sensitivity functi
Externí odkaz:
https://doaj.org/article/3bc00750c5774307bb80084a64d44ed5
Autor:
Michaela Ducháčková, Karel Fliegel, Ladislav Dušek, Tomas Lukes, Rudolf Autrata, Jan Hejda, Miroslav Dostálek, Jiri Hozman
Publikováno v:
Journal of Eye Movement Research; Bd. 12 Nr. 4 (2019): Special Thematic Issue "Vergence Eye Movements: From basic science to clinical application"
Journal of Eye Movement Research; Vol. 12 No. 4 (2019): Special Thematic Issue "Vergence Eye Movements: From basic science to clinical application"
Journal of Eye Movement Research
Journal of Eye Movement Research, Vol 12, Iss 4 (2019)
Journal of Eye Movement Research; Vol. 12 No. 4 (2019): Special Thematic Issue "Vergence Eye Movements: From basic science to clinical application"
Journal of Eye Movement Research
Journal of Eye Movement Research, Vol 12, Iss 4 (2019)
The stability of fusion was evaluated by its breakage when interocular blur differences were presented under vergence demand to healthy subjects. We presumed that these blur differences cause suppression of the more blurred image (interocular blur su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9d128e84a7630300b195afb37cdd2f
https://doi.org/10.16910/jemr.12.4.4
https://doi.org/10.16910/jemr.12.4.4
Publikováno v:
mAbs. 9(5)
Pharmacokinetic studies play an important role in all stages of drug discovery and development. Recent advancements in the tools for discovery and optimization of therapeutic proteins have created an abundance of candidates that may fulfill target pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed08bcc24778b807b99ad73f4a4ef42c
https://pubmed.ncbi.nlm.nih.gov/28463063
https://pubmed.ncbi.nlm.nih.gov/28463063
Publikováno v:
The AAPS Journal. 16:1097-1109
Compared to small chemical molecules, monoclonal antibodies and Fc-containing derivatives (mAbs) have unique pharmacokinetic behaviour characterised by relatively poor cellular permeability, minimal renal filtration, binding to FcRn, target-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6701dec6f9333dc898ab69167a79f2f2
https://doi.org/10.1208/s12248-014-9640-5
https://doi.org/10.1208/s12248-014-9640-5
Publikováno v:
Molecular Immunology. 56:660-674
F.W.R. Brambell deduced the existence of a protective receptor for IgG, the neonatal Fc receptor (FcRn), long before its discovery in the early to mid-1990s. With the coincident, explosive development of IgG-based drugs, FcRn became a popular target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef8ef50d64da3d13fe9743ec1eace3a
https://doi.org/10.1016/j.molimm.2013.05.008
https://doi.org/10.1016/j.molimm.2013.05.008
Autor:
Everson Nogoceke, Kay Stubenrauch, Chui Ming Gemmy Cheung, Peter Lundh von Leithner, Sai Bo Bo Tun, Jörg Moelleken, Pamela Strassburger, Yeo Sia Wey, Daiju Iwata, David T. Shima, Gabriella Widmer, Jörg T. Regula, Veluchamy A Barathi, Michael Janusz Koss, Miroslav Dostálek, Christian Klein, Guido Hartmann, Richard Foxton
Publikováno v:
EMBO Molecular Medicine
Anti‐angiogenic therapies using biological molecules that neutralize vascular endothelial growth factor‐A (VEGF‐A) have revolutionized treatment of retinal vascular diseases including age‐related macular degeneration (AMD). This study reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7449ecfde7f87b302f93b6564a7eb94d
https://pubmed.ncbi.nlm.nih.gov/31040127
https://pubmed.ncbi.nlm.nih.gov/31040127
Autor:
Wai-Johnn Sam, Komal R. Paryani, Reginald Y. Gohh, Fatemeh Akhlaghi, Joyce S. Macwan, Miroslav Dostálek
Publikováno v:
Clinical Pharmacokinetics. 51:591-606
Patients with diabetes mellitus might be at a higher risk of HMG-CoA reductase inhibitor (statin)-induced myotoxicity, possibly because of reduced clearance of the statin lactone. The present study was designed to investigate the effect of diabetes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14f245d4471773bd1fc5aaede987d549
https://doi.org/10.1007/bf03261933
https://doi.org/10.1007/bf03261933
Publikováno v:
Clinical Pharmacokinetics. 51:481-499
The effects of diabetes mellitus on the pharmacokinetics and pharmacodynamics of drugs have been well described in experimental animal models; however, only minimal data exist for humans and the current knowledge regarding the effects of diabetes on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8820584318fdf60ff711084242461ea7
https://doi.org/10.1007/bf03261926
https://doi.org/10.1007/bf03261926
Autor:
Anders Åsberg, Fatemeh Akhlaghi, Rune Amundsen, Miroslav Dostálek, Reginald Y. Gohh, Anisha E. Mendonza, Pål Falck
Publikováno v:
Therapeutic Drug Monitoring. 34:38-45
Diabetes mellitus is prevalent among kidney transplant recipients. The activity of drug metabolizing enzymes or transporters may be altered by diabetes leading to changes in the concentration of parent drug or metabolites. This study was aimed to cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51e497b3d26901be5b71a9357cc35e8
https://doi.org/10.1097/ftd.0b013e318241ac71
https://doi.org/10.1097/ftd.0b013e318241ac71