A Comprehensive Atlas of AAV Tropism in the Mouse.

Autor: Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, Gaitan Y, Duryea J, Hannigan S, Dickinson ME, Mirochnitchenko O, Wang D, Lutz CM, Heaney JD, Gao G, Murray SA, Lagor WR

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 10. Date of Electronic Publication: 2024 Sep 10.

Attenuation of 6‐OHDA‐induced neurotoxicity in glutathione peroxidase transgenic mice.

Autor: Bensadoun, J. C.¹ (AUTHOR), Mirochnitchenko, O.^1,2 (AUTHOR), Inouye, M.^1,2 (AUTHOR), Aebischer, P.¹ (AUTHOR), Zurn, A. D.¹ (AUTHOR)

Publikováno v: European Journal of Neuroscience. Oct98, Vol. 10 Issue 10, p3231-3236. 6p. 1 Chart.

The NIH Somatic Cell Genome Editing program.

Autor: Saha K; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu.; Department of Medical History & Bioethics, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu.; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu., Sontheimer EJ; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA. erik.sontheimer@umassmed.edu., Brooks PJ; Office of Rare Diseases Research, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Bethesda, MD, USA., Dwinell MR; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA., Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Liu DR; Merkin Institute of Transformative Technologies, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Murray SA; The Jackson Laboratory, Bar Harbor, ME, USA., Tsai SQ; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA., Wilson RC; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Anderson DG; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology, Cambridge, MA, USA., Asokan A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, USA., Banfield JF; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, Berkeley, CA, USA., Bankiewicz KS; Department of Neurological Surgery, Ohio State University, Columbus, OH, USA., Bao G; Department of Bioengineering, Rice University, Houston, TX, USA., Bulte JWM; Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Bursac N; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Campbell JM; Recombinetics, Inc, Eagan, MN, USA., Carlson DF; Recombinetics, Inc, Eagan, MN, USA., Chaikof EL; Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA., Chen ZY; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.; Program in Neuroscience, Harvard Medical School, Boston, MA, USA.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA, USA., Cheng RH; Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA, USA., Clark KJ; Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN, USA., Curiel DT; Department of Radiation Oncology, Washington University in St Louis, St Louis, MO, USA., Dahlman JE; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Deverman BE; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Dickinson ME; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Doudna JA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA., Ekker SC; Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN, USA., Emborg ME; Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Feng G; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Freedman BS; Division of Nephrology, University of Washington, Seattle, WA, USA.; Kidney Research Institute, University of Washington, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA., Gamm DM; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Gao G; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA, USA., Ghiran IC; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Glazer PM; Department of Therapeutic Radiology, Yale University, New Haven, CT, USA., Gong S; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA., Heaney JD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Hennebold JD; Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Hinson JT; Pat and Jim Calhoun Cardiology Center, University of Connecticut School of Medicine, Farmington, CT, USA., Khvorova A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Kiani S; Pittsburgh Liver Research Center, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Lam KS; Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, USA., Leong KW; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Levine JE; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Lewis JA; Wyss Institute, Harvard University, Cambridge, MA, USA., Lutz CM; The Jackson Laboratory, Bar Harbor, ME, USA., Ly DH; Department of Chemistry, Carnegie-Mellon University, Pittsburgh, PA, USA., Maragh S; Biomarker and Genomic Sciences Group, National Institute of Standards and Technology, Gaithersburg, MD, USA., McCray PB Jr; Department of Pediatrics, University of Iowa, Iowa City, IA, USA., McDevitt TC; Gladstone Institute of Cardiovascular Disease, Gladstone Institutes, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA., Mirochnitchenko O; Office of Research Infrastructure Programs, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA., Morizane R; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Murthy N; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Prather RS; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Ronald JA; Robarts Research Institute and Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada., Roy S; Department of Pathology, University of California, San Diego, La Jolla, CA, USA., Roy S; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Sabbisetti V; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Saltzman WM; Department of Biomedical Engineering, Yale University, New Haven, CT, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Segal DJ; Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, USA., Shimoyama M; Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, Milwaukee, WI, USA., Skala MC; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA., Tarantal AF; Department of Pediatrics, University of California, Davis, Davis, CA, USA.; Department of Cell Biology and Human Anatomy, University of California, Davis, Davis, CA, USA.; School of Medicine, University of California, Davis, Davis, CA, USA.; California National Primate Research Center, University of California, Davis, Davis, CA, USA., Tilton JC; Department of Nutrition, Case Western Reserve University, Cleveland, OH, USA., Truskey GA; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Vandsburger M; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Watts JK; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Wells KD; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Wolfe SA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Worcester, MA, USA., Xu Q; Department of Biomedical Engineering, Tufts University, Medford, MA, USA., Xue W; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Yi G; Department of Pulmonary Immunology, University of Texas Health Sciences Center at Tyler, Tyler, TX, USA., Zhou J; Department of Neurosurgery, Yale University, New Haven, CT, USA.

Publikováno v: Nature [Nature] 2021 Apr; Vol. 592 (7853), pp. 195-204. Date of Electronic Publication: 2021 Apr 07.

The updated mouse universal genotyping array bioinformatic pipeline improves genetic QC in laboratory mice.

Autor: Blanchard, Matthew W^1,2 (AUTHOR), Sigmon, John Sebastian^2,3 (AUTHOR), Brennan, Jennifer² (AUTHOR), Ahulamibe, Chidima¹ (AUTHOR), Allen, Michelle E^1,4 (AUTHOR), Ardery, Sam⁵ (AUTHOR), Baric, Ralph S⁶ (AUTHOR), Bell, Timothy A¹ (AUTHOR), Farrington, Joseph¹ (AUTHOR), Ciavatta, Dominic^1,2 (AUTHOR), Cisneros, Marta C Cruz^1,5 (AUTHOR), Drushal, Madison^1,4 (AUTHOR), Ferris, Martin T^1,4 (AUTHOR), Fry, Rebecca C⁷ (AUTHOR), Gaines, Christiann¹ (AUTHOR), Gu, Bin⁸ (AUTHOR), Heise, Mark T¹ (AUTHOR), Hock, Pablo¹ (AUTHOR), Hodges, Richard Austin^1,4 (AUTHOR), Hulgin, Mia⁴ (AUTHOR)

Publikováno v: G3: Genes | Genomes | Genetics. Oct2024, Vol. 14 Issue 10, p1-9. 9p.

Humanized immune system mouse models: progress, challenges and opportunities.

Autor: Allen TM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Brehm MA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA., Bridges S; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, National Institutes of Health, Rockville, MD, USA., Ferguson S; Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Kumar P; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA., Mirochnitchenko O; Office of Research Infrastructure Programs, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA., Palucka K; The Jackson Laboratory, Farmington, CT, USA., Pelanda R; Department of Immunology and Microbiology, University of Colorado, Aurora, CO, USA., Sanders-Beer B; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, National Institutes of Health, Rockville, MD, USA., Shultz LD; The Jackson Laboratory, Bar Harbor, ME, USA., Su L; University of North Carolina, Chapel Hill, Chapel Hill, NC, USA., PrabhuDas M; Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA. mprabhudas@niaid.nih.gov.

Publikováno v: Nature immunology [Nat Immunol] 2019 Jul; Vol. 20 (7), pp. 770-774.