Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Miro E. Raeber"'
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104539- (2023)
Summary: Background: The cytokine interleukin-2 (IL-2) can stimulate both effector immune cells and regulatory T (Treg) cells. The ability of selectively engaging either of these effects has spurred interest in using IL-2 for immunotherapy of cancer
Externí odkaz:
https://doaj.org/article/6f24eb0b735344ddbb97e4d54971d983
Autor:
Carlo Cervia, Yves Zurbuchen, Patrick Taeschler, Tala Ballouz, Dominik Menges, Sara Hasler, Sarah Adamo, Miro E. Raeber, Esther Bächli, Alain Rudiger, Melina Stüssi-Helbling, Lars C. Huber, Jakob Nilsson, Ulrike Held, Milo A. Puhan, Onur Boyman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Studying a prospective cohort, the authors develop and validate a predictive score for post-acute COVID-19 syndrome, also known as long-COVID. This score relies on an immunoglobulin signature and is independent of timepoint of blood sampling.
Externí odkaz:
https://doaj.org/article/79cffcd777124d548463576add3f9a75
Publikováno v:
Medicina, Vol 59, Iss 3, p 488 (2023)
Achieving adequate immunosuppression for lung transplant recipients in the first year after lung transplantation is a key challenge. Prophylaxis of allograft rejection must be balanced with the adverse events associated with immunosuppressive drugs,
Externí odkaz:
https://doaj.org/article/f441d04d34cd4c76885318d52342a601
Autor:
Michelle Schorer, Katharina Lambert, Nikolas Rakebrandt, Felix Rost, Kung-Chi Kao, Alexander Yermanos, Roman Spörri, Josua Oderbolz, Miro E. Raeber, Christian W. Keller, Jan D. Lünemann, Gerhard Rogler, Onur Boyman, Annette Oxenius, Nicole Joller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Viral infection transiently depletes T regulatory cells (Treg). Here the authors identify a compensatory induced Treg population, which is required to rapidly replenish the Treg niche and suppress microbiota-driven, virus-induced colitis.
Externí odkaz:
https://doaj.org/article/358d973756854a01949a43086610135a
1.AbstractBackgroundLow-dose interleukin-2 (IL-2) shows promise as a treatment for restoring functional and numerical deficits of regulatory T (Treg) cells in patients with various autoimmune diseases. Several clinical trials testing low-dose IL-2 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8edc3acae055fc865d509ca31d3f131b
https://doi.org/10.1101/2022.12.02.22283038
https://doi.org/10.1101/2022.12.02.22283038
Autor:
Miro E. Raeber, Dominic Caspar, Yves Zurbuchen, Nannan Guo, Jonas Schmid, Jan Michler, Urs C. Steiner, Andreas E. Moor, Frits Koning, Onur Boyman
Due to its stimulatory potential for immunomodulatory CD4+regulatory T (Treg) cells, low-dose interleukin-2 (IL-2) immunotherapy has recently gained considerable attention for treatment of various autoimmune diseases. Although early-stage clinical tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a46cb8334a6ccf0d7b994a269bb0a5a
https://doi.org/10.1101/2022.11.15.22282201
https://doi.org/10.1101/2022.11.15.22282201
Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have resulted in the development of improved IL-2 formulations with IL-2 receptor bias and tissue-targeting properties. Several of these compounds are cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8eb34348255a653686d305bf74ae467
https://www.zora.uzh.ch/id/eprint/229260/
https://www.zora.uzh.ch/id/eprint/229260/
Autor:
Yves Zurbuchen, Jan Michler, Patrick Taeschler, Sarah Adamo, Carlo Cervia, Miro E. Raeber, Ilhan E. Acar, Jakob Nilsson, Michael B. Soyka, Andreas E. Moor, Onur Boyman
B cell responses to different pathogens recruit tailored effector mechanisms, resulting in functionally specialized subsets. For human memory B cells (MBCs), these include CD21+ resting, CD21−CD27+ activated, and CD21−CD27− atypical cells. Whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0e4e4f4fcd704af9c532c2a4a12942b
https://doi.org/10.1101/2022.10.07.511336
https://doi.org/10.1101/2022.10.07.511336
Autor:
Sujana Sivapatham, Sarah Adamo, Dominik J. Schaer, Melina Stüssi-Helbling, Stéphane Chevrier, Miro E. Raeber, Esther Baechli, Jakob Nilsson, Lars C. Huber, Andrea Jacobs, Liliane Yang, Alain Rudiger, Carlo Cervia, Bernd Bodenmiller, Onur Boyman, Yves Zurbuchen
Publikováno v:
Allergy
Allergy, 76 (9)
Allergy, 76 (9)
Background Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and shows a broad clinical presentation ranging from asymptomatic infection to fatal disease. A very prominent fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265e5923615533f8be059078ce3686d8
https://doi.org/10.1111/all.14866
https://doi.org/10.1111/all.14866
Publikováno v:
Medicina. 59:488
Achieving adequate immunosuppression for lung transplant recipients in the first year after lung transplantation is a key challenge. Prophylaxis of allograft rejection must be balanced with the adverse events associated with immunosuppressive drugs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da4cb62e120ad02ac86ea0a5cc3e301c
https://doi.org/10.3390/medicina59030488
https://doi.org/10.3390/medicina59030488