Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Mirna Mourtada-Maarabouni"'
Publikováno v:
Non-Coding RNA, Vol 9, Iss 4, p 47 (2023)
Myocardial Infarction Associated Transcript (MIAT) is a nuclear long non-coding RNA (LncRNA) with four different splicing variants. MIAT dysregulation is associated with carcinogenesis, mainly acting as an oncogene regulating cellular growth, invasio
Externí odkaz:
https://doaj.org/article/a0234f71c33f4a43abd4dccf265a6992
Publikováno v:
The Scientific World Journal, Vol 2, Pp 1885-1890 (2002)
The candidate tumour suppressor gene, LUCA-15, maps to the lung cancer tumour suppressor locus 3p21.3. The LUCA-15 gene locus encodes at least four alternatively spliced transcripts, which have been shown to function as regulators of apoptosis, a fac
Externí odkaz:
https://doaj.org/article/552d6a1bef724d2fb4ce6579b3af3927
Regulation of T-Cell Apoptosis by Sequences Encoded at the Luca-15 Candidate Tumour Suppressor Locus
Autor:
Mirna Mourtada-Maarabouni, Leslie C. Sutherland, Jeremy P. Clark, Colin S. Cooper, Gwyn T. Williams
Publikováno v:
The Scientific World Journal, Vol 1, Pp 38-38 (2001)
Externí odkaz:
https://doaj.org/article/78f3448339ed4f76966e3631407066a3
Publikováno v:
International Journal of Biological Macromolecules. 233:123467
Autor:
Mirna Mourtada-Maarabouni, Eric A. Ortlund, Filipp Frank, Eric B. Dammer, Nadieh Kavousi, Aikaterina Bountali
Publikováno v:
Journal of the Endocrine Society
The growth arrest-specific 5 (gas5) gene encodes a long non-coding RNA (lncRNA) that is required for normal growth arrest, slows down the cell cycle, controls apoptosis, and is required for the inhibition of cell growth by mTOR inhibitors such as rap
Publikováno v:
Cellular Signalling. 28:1389-1400
Background:\ud The control of breast cell survival is of critical importance for preventing breast cancer initiation and progression. The activity of many proteins which regulate cell survival is controlled by reversible phosphorylation, so that the
Myocardial Infarction Associated Transcript (MIAT) is a subnuclear lncRNA that interferes with alternative splicing and is associated with increased risk of various heart conditions and nervous system tumours. The current study aims to elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3635cfa11407855dc5dc575b86faa5
Autor:
Mirna Mourtada-Maarabouni, Eric A. Ortlund, Aikaterini Bountali, Nadieh Kavousi, Filipp Frank, Eric B. Dammer
Publikováno v:
Cell Reports. 32:107933
Summary There is increasing evidence that the architecture of long non-coding RNAs (lncRNAs)—just like that of proteins—is hierarchically organized into independently folding sub-modules with distinct functions. Studies characterizing the cellula
Publikováno v:
ESMO Open. 3:A365-A366
Introduction Of the total human DNA only 1.2% o codes for proteins, with the rest only being transcribed into regulatory RNA, known as non-coding RNA. Long non-coding RNAs (lncRNAs) are non-coding RNAs that have no or limited protein-coding potential
Publikováno v:
ResearcherID
Targets for cancer therapy are conventionally selected by identification of molecules acting downstream of established tumour suppressors and oncoproteins, such as p53, c-Myc and Ras. However, the forward genetics approach provides an alternative, co