Výsledky vyhledávání - "Mirna McDonald"

Akademický článek

Reslizumab as add-on therapy in patients with refractory asthma

Autor: J Christian Virchow, Mirna McDonald, Margaret Garin, Stephanie Korn

Publikováno v: BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)

Externí odkaz: https://doaj.org/article/1b56b1c5d35c4322876d39107df71d36

Pharmacokinetics, metabolism and safety of deuterated L-DOPA (SD-1077)/carbidopa compared to L-DOPA/carbidopa following single oral dose administration in healthy subjects

Autor: Hooman Beygi, Igor D. Grachev, Juha-Matti Savola, Micha Levi, Serge Guzy, Margaret Bradbury, Pippa S. Loupe, Lavi Erisson, Ofer Spiegelstein, Maria Velinova, Spyros Papapetropoulos, William Tracewell, Mirna McDonald, Orit Cohen-Barak, Frank Schneider

Publikováno v: British Journal of Clinical Pharmacology. 84:2422-2432

AIMS SD-1077, a selectively deuterated precursor of dopamine (DA) structurally related to L-3,4-dihydroxyphenylalanine (L-DOPA), is under development for treatment of motor symptoms of Parkinson's disease. Preclinical models have shown slower metabol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66afb0fc32dce1d2a72c8a6e5722f9e3
https://doi.org/10.1111/bcp.13702

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Sustained reductions in migraine days, moderate-to-severe headache days and days with acute medication use for HFEM and CM patients taking fremanezumab: Post-hoc analyses from phase 2 trials

Autor: Ernesto Aycardi, Marcelo E. Bigal, Rashmi B. Halker Singh, David W. Dodick, Pippa S. Loupe, Mirna McDonald

Publikováno v: Cephalalgia. 39:52-60

Background In phase 2 and 3 studies, fremanezumab, a monoclonal CGRP antibody, was an effective preventive treatment for high-frequency episodic migraine (HFEM) and chronic migraine (CM). Objective Post-hoc analyses evaluated population-wise 50%, 75%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70608901866d9007d7bebda0b9d63720
https://doi.org/10.1177/0333102418772585

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Effect of intravenously administered reslizumab on spirometric lung age in patients with moderate-to-severe eosinophilic asthma

Autor: Warner W Carr, Mirna McDonald, Paige Meizlik

Publikováno v: Allergy and asthma proceedings. 40(4)

Background: Spirometric lung age expresses lung function relative to chronological age. It has been effective in encouraging smoking cessation and has been used in the assessment of asthma. Reslizumab, a humanized anti-interleukin-5 monoclonal antibo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952325b1f5d978cc5df26b869d45359f
https://pubmed.ncbi.nlm.nih.gov/31262379

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Reslizumab as add-on therapy in patients with refractory asthma

Autor: Stephanie Korn, Margaret Garin, J. Christian Virchow, Mirna McDonald

Publikováno v: BMJ Open Respiratory Research
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)

Key messages #### What is the key question? #### What is the bottom line? #### Why read on? Asthma is a common disease, affecting an estimated 334 million people worldwide, with considerable impact on quality of life and high associated costs.1–3 A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a47733bba39c7cb36d494b86ae55fe
https://doi.org/10.1136/bmjresp-2019-000494

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Pharmacokinetics, metabolism and safety of deuterated L-DOPA (SD-1077)/carbidopa compared to L-DOPA/carbidopa following single oral dose administration in healthy subjects

Autor: Frank, Schneider, Lavi, Erisson, Hooman, Beygi, Margaret, Bradbury, Orit, Cohen-Barak, Igor D, Grachev, Serge, Guzy, Pippa S, Loupe, Micha, Levi, Mirna, McDonald, Juha-Matti, Savola, Spyros, Papapetropoulos, William G, Tracewell, Maria, Velinova, Ofer, Spiegelstein

Publikováno v: British journal of clinical pharmacology. 84(10)

SD-1077, a selectively deuterated precursor of dopamine (DA) structurally related to L-3,4-dihydroxyphenylalanine (L-DOPA), is under development for treatment of motor symptoms of Parkinson's disease. Preclinical models have shown slower metabolism o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a79b98d8baa7e8ab3ceb6e5e17bd386f
https://pubmed.ncbi.nlm.nih.gov/29959802

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