Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mirko Cevec"'
Autor:
George E. Fox, Melanie Ziegeler, Parin Sripakdeevong, Ryszard Kierzek, Scott D. Kennedy, Xiaolian Gao, Edward P. Nikonowicz, Roland K. O. Sigel, Michèle C. Erat, Harald Schwalbe, Qin Zhao, Andrew T. Chang, Douglas H. Turner, Rhiju Das, Mirko Cevec
Publikováno v:
Nature methods
Nature Methods
Nature Methods
Structured noncoding RNAs underlie fundamental cellular processes, but determining their three-dimensional structures remains challenging. We demonstrate that integrating 1H NMR chemical shift data with Rosetta de novo modeling can be used to consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a690c9cb49ce228868403c8f783923c2
http://europepmc.org/articles/PMC3985481
http://europepmc.org/articles/PMC3985481
Publikováno v:
Journal of Biomolecular NMR. 57:1-9
A 4D (13)C(aromatic),(13)C(ribose)-edited NOESY experiment is introduced to improve sequential assignment of non-coding RNA, often hampered by a limited dispersion of (1)H and (13)C chemical shifts. The (13)C-labeling of RNA is fully utilized by incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7984542d0c806f6ea485b321e693692
https://doi.org/10.1007/s10858-013-9771-5
https://doi.org/10.1007/s10858-013-9771-5
Publikováno v:
Nucleic Acids Research
We have determined the 3D structure of a 34-nt RNA construct, herein named LCS1co, which mimics the interaction of let-7 microRNA (miRNA) to one of its complementary binding sites, LCS1, in the 3′-untranslated region of lin-41 mRNA by solution-stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3255bb9aeb194e4c5b16bad007d3f1c6
http://europepmc.org/articles/PMC2995062
http://europepmc.org/articles/PMC2995062
Publikováno v:
Nucleic Acids Research
let-7 microRNA (miRNA) regulates heterochronic genes in developmental timing of the nematode Caenorhabditis elegans. Binding of miRNA to messenger RNA (mRNA) and structural features of the complex are crucial for gene silencing. We herein present the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99574e65ad5465ca78ca6e11a87b0d7f
http://europepmc.org/articles/PMC2367737
http://europepmc.org/articles/PMC2367737
Publikováno v:
Journal of Biomolecular Nmr
The three-dimensional structure determination of RNAs by NMR spectroscopy requires sequential resonance assignment, often hampered by assignment ambiguities and limited dispersion of (1)H and (13)C chemical shifts, especially of C4'/H4'. Here we pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d1385a4eca63f853b04050403bf01c
https://pubmed.ncbi.nlm.nih.gov/26409925
https://pubmed.ncbi.nlm.nih.gov/26409925
Publikováno v:
Biochimie. 95(12)
The solution-state structure of 2′- O -(2-methoxyethly) substituted dodecamer r(*CG*CGAA*U*U*CG*C)d(G), 2′-MOE RNA, with all cytosines and uracils methylated at the C5-position has been determined by NMR spectroscopy. The chemical modifications w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8168adf4d8e2a5aecaf4c6549caeffa
https://pubmed.ncbi.nlm.nih.gov/24012551
https://pubmed.ncbi.nlm.nih.gov/24012551
Publikováno v:
Chembiochem : a European journal of chemical biology. 13(14)
Comparative genomics has shown that noncoding RNAs can display substantial differences between humans and chimpanzees. The human accelerated region 1 (HAR1) is a section in the human genome that exhibits the most strongly accelerated rate of nucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446e07fec26edf80091084aee093c4ba
https://pubmed.ncbi.nlm.nih.gov/22961937
https://pubmed.ncbi.nlm.nih.gov/22961937
Autor:
Francesca Cantini, Hendrik R. A. Jonker, Mirko Cevec, Christian Richter, Senada Nozinovic, Lucia Banci, Harald Schwalbe
Publikováno v:
NMR of Biomolecules: Towards Mechanistic Systems Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ecdbbbc49349bf253879989e2cffe0
https://doi.org/10.1002/9783527644506.ch2
https://doi.org/10.1002/9783527644506.ch2
Autor:
Mirko, Cevec, Janez, Plavec
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 667
The use of contemporary nuclear magnetic resonance (NMR) methods in the studies of model systems between microRNA (miRNA) and messenger RNA (mRNA) is reviewed. We describe our studies on structural features of 33-nt RNA model construct between let-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27819e2c3af77bc284860aace04ff4a0
https://pubmed.ncbi.nlm.nih.gov/20827539
https://pubmed.ncbi.nlm.nih.gov/20827539
Autor:
Mirko Cevec, Janez Plavec
Publikováno v:
Methods in Molecular Biology ISBN: 9781607618102
The use of contemporary nuclear magnetic resonance (NMR) methods in the studies of model systems between microRNA (miRNA) and messenger RNA (mRNA) is reviewed. We describe our studies on structural features of 33-nt RNA model construct between let-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a58d3d625434623aece038924c819b18
https://doi.org/10.1007/978-1-60761-811-9_17
https://doi.org/10.1007/978-1-60761-811-9_17