Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Mirko, Pham"'
Autor:
Jan Traub, György Homola, Caroline Morbach, Roxanne Sell, Dennis Göpfert, Stefan Frantz, Mirko Pham, Guido Stoll, Stefan Störk, Anna Frey
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3191-3199 (2024)
Abstract Aims Cognitive impairment (CI) is a common, yet frequently unrecognized co‐morbidity in chronic heart failure (HF). We quantified trajectories of cognitive performance, brain volume, and related clinical outcome over a time course of 6 yea
Externí odkaz:
https://doaj.org/article/161d107e3b3e4fbc9919de45c04321d7
Autor:
Andreas Starke, Alexander M. Kollikowski, Vivian Vogt, Guido Stoll, Bernhard Nieswandt, Mirko Pham, David Stegner, Michael K. Schuhmann
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2191 (2024)
Background: Severe acute ischemic stroke (AIS) is mainly caused by thromboembolism originating from symptomatic carotid artery (ICA) stenosis or in the heart due to atrial fibrillation. Glycoprotein VI (GPVI), a principal platelet receptor, facilitat
Externí odkaz:
https://doaj.org/article/f668caeb58f740a484fde12cd765f6f1
Autor:
Alexander M. Kollikowski, Mirko Pham, Alexander G. März, Jörn Feick, Marius L. Vogt, Yanyan Xiong, Marc Strinitz, Christoph Vollmuth, Fabian Essig, Hermann Neugebauer, Karl Georg Haeusler, Christian Hametner, Lena Zimmermann, Guido Stoll, Michael K. Schuhmann
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105095- (2024)
Summary: Background: Matrix metalloproteinases (MMPs) are implied in blood–brain barrier degradation and haemorrhagic transformation following ischaemic stroke, but their local relevance in the hyperacute disease phase is unknown. We aimed to exami
Externí odkaz:
https://doaj.org/article/6cbc00f3ba454381a890f3ccf41b2636
Autor:
Lorenzo Barba, Christoph Vollmuth, Samir Abu-Rumeileh, Steffen Halbgebauer, Patrick Oeckl, Petra Steinacker, Alexander M. Kollikowski, Cara Schultz, Judith Wolf, Mirko Pham, Michael K. Schuhmann, Peter U. Heuschmann, Karl Georg Haeusler, Guido Stoll, Hermann Neugebauer, Markus Otto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract We aimed to assess the prognostic value of serum β-synuclein (β-syn), neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in patients with moderate-to-severe acute ischemic stroke. We measured β-syn, GFAP and NfL in
Externí odkaz:
https://doaj.org/article/e4b568f07c824155bc3dfb236de0636a
Autor:
Jan Traub, Mira Schließer, Caroline Morbach, Stefan Frantz, Mirko Pham, Stefan Störk, Guido Stoll, Anna Frey, Hermann Neugebauer
Publikováno v:
ESC Heart Failure, Vol 10, Iss 5, Pp 3203-3208 (2023)
Abstract Aims Mild cognitive impairment and dementia are common and serious co‐morbidities in people with chronic heart failure (HF) as they increase hospitalization rates, mortality and health care costs. Upon other factors, dysregulated cerebral
Externí odkaz:
https://doaj.org/article/0724e48122e84765ab8f91bfdcd420c4
Autor:
Xiang Zhou, Seungbin Han, Nadine Cebulla, Larissa Haertle, Maximilian J. Steinhardt, Daniel Schirmer, Eva Runau, Leon Flamm, Calvin Terhorst, Laura Jähnel, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Julia Mersi, Umair Munawar, Magnus Schindehütte, Robert Blum, Ann-Kristin Reinhold, Oliver Scherf-Clavel, Heike L. Rittner, Mirko Pham, Leo Rasche, Hermann Einsele, Claudia Sommer, K. Martin Kortüm
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-4 (2023)
Abstract We analyzed single nucleotide polymorphisms (SNPs) in PKNOX1 (rs2839629) and in the intergenic region between PKNOX1 and CBS (rs915854) by Sanger sequencing in 88 patients with multiple myeloma treated with bortezomib. All patients (n = 13)
Externí odkaz:
https://doaj.org/article/e043da7190114504a5058138355ee591
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundNeuromyelitis optica spectrum disorder (NMOSD) is a devastating inflammatory disease of the central nervous system that is often severely disabling from the outset. The lack of pathognomonic aquaporin 4 (AQP4) antibodies in seronegative NMO
Externí odkaz:
https://doaj.org/article/c1351b18489846df877cbdae443511c3
Autor:
Jan Traub, Markus Otto, Roxane Sell, Dennis Göpfert, György Homola, Petra Steinacker, Patrick Oeckl, Caroline Morbach, Stefan Frantz, Mirko Pham, Stefan Störk, Guido Stoll, Anna Frey
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Chronic heart failure (HF) is known to increase the risk of developing Alzheimer’s dementia significantly. Thus, detecting and preventing mild cognitive impairment, which is common in patients with HF, is of great importance. Se
Externí odkaz:
https://doaj.org/article/f55de37237124c76ad76b1e457426664
Autor:
Jan Traub, Markus Otto, Roxane Sell, György A. Homola, Petra Steinacker, Patrick Oeckl, Caroline Morbach, Stefan Frantz, Mirko Pham, Stefan Störk, Guido Stoll, Anna Frey
Publikováno v:
ESC Heart Failure, Vol 9, Iss 4, Pp 2626-2634 (2022)
Abstract Aims Cognitive dysfunction occurs frequently in patients with heart failure (HF), but early detection remains challenging. Serum glial fibrillary acidic protein (GFAP) is an emerging biomarker of cognitive decline in disorders of primary neu
Externí odkaz:
https://doaj.org/article/e660f4b5906f488185232edc894a2898
Autor:
Dennis Göpfert, Jan Traub, Roxane Sell, György A. Homola, Marius Vogt, Mirko Pham, Stefan Frantz, Stefan Störk, Guido Stoll, Anna Frey
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
BackgroundCognitive impairment is a major comorbidity in patients with chronic heart failure (HF) with a wide range of phenotypes. In this study, we aimed to identify and compare different clusters of cognitive deficits.MethodsThe prospective cohort
Externí odkaz:
https://doaj.org/article/e352006f873e469ca71b616836290c99