Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Mirkka Sarparanta"'
Autor:
Shiqi Wang, Mariia V. Shcherbii, Sami-Pekka Hirvonen, Gudrun Silvennoinen, Mirkka Sarparanta, Hélder A. Santos
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Efficient intracellular delivery is crucial for biotherapeutics, such as proteins, oligonucleotides, and CRISPR/Cas9 gene-editing systems, to achieve their efficacy. Despite the great efforts of developing new intracellular delivery carriers
Externí odkaz:
https://doaj.org/article/37b1820ba66b4d2fa4c018750caf3ef8
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Surachet Imlimthan, Olli Aitio, Mirkka Sarparanta, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecules, Vol 29, Iss 17, p 4263 (2024)
Boron Neutron Capture Therapy (BNCT) is a cancer treatment which combines tumor-selective boron delivery agents with thermal neutrons in order to selectively eradicate cancer cells. In this work, we focus on the early-stage development of carbohydrat
Externí odkaz:
https://doaj.org/article/9c47b19bd5b341ce9b2e8aff4ce2ab60
Autor:
Outi Keinänen, Eric J. Dayts, Cindy Rodriguez, Samantha M. Sarrett, James M. Brennan, Mirkka Sarparanta, Brian M. Zeglis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The proliferation of plastics in the environment continues at an alarming rate. Plastic particles have been found to be persistent and ubiquitous pollutants in a variety of environments, including sea water, fresh water, soil, and air. In li
Externí odkaz:
https://doaj.org/article/1dc3c5928bad4f8db06b2d7fd448c29b
Autor:
Outi Keinänen, Kimberly Fung, Jacob Pourat, Vilma Jallinoja, Delphine Vivier, NagaVara Kishore Pillarsetty, Anu J. Airaksinen, Jason S. Lewis, Brian M. Zeglis, Mirkka Sarparanta
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Background Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient. To date, only a few studies have used short-lived radioisotopes for pret
Externí odkaz:
https://doaj.org/article/0fcf170bc14143cab53aa92849dad3cf
Autor:
Outi Keinänen, Ermei M. Mäkilä, Rici Lindgren, Helena Virtanen, Heidi Liljenbäck, Vesa Oikonen, Mirkka Sarparanta, Carla Molthoff, Albert D. Windhorst, Anne Roivainen, Jarno J. Salonen, Anu J. Airaksinen
Publikováno v:
ACS Omega, Vol 2, Iss 1, Pp 62-69 (2017)
Externí odkaz:
https://doaj.org/article/bdf5cede6ff949c596ca835fed9799c3
Autor:
Sofia Otaru, Surachet Imlimthan, Mirkka Sarparanta, Kerttuli Helariutta, Kristiina Wähälä, Anu J. Airaksinen
Publikováno v:
Molecules, Vol 25, Iss 5, p 1208 (2020)
Fluorine-18 is the most widely used positron emission tomography (PET) radionuclide currently in clinical application, due to its optimal nuclear properties. The synthesis of 18F-labeled radiotracers often requires harsh reaction conditions, limiting
Externí odkaz:
https://doaj.org/article/3761c67f6f47490b89366babef7a14ef
Autor:
Maria Rajecki, Mirkka Sarparanta, Tanja Hakkarainen, Mikko Tenhunen, Iulia Diaconu, Venla Kuhmonen, Kalevi Kairemo, Anna Kanerva, Anu J Airaksinen, Akseli Hemminki
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32871 (2012)
Oncolytic adenoviruses can be engineered for better tumor selectivity, gene delivery and be armed for imaging and concentrating radionuclides into tumors for synergistic oncolysis. We constructed Ad5/3-hTERT-hNIS where replication is controlled by hT
Externí odkaz:
https://doaj.org/article/e17cf8fdf1f44f05a7bd565386ab942e
Autor:
Jelena Matović, Katayun Bahrami, Philipp Stockmann, Iris K. Sokka, You Cheng Khng, Mirkka Sarparanta, Evamarie Hey-Hawkins, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c1e4a225677d7dd5243d38b06858293
https://doi.org/10.1021/acs.molpharmaceut.3c00119
https://doi.org/10.1021/acs.molpharmaceut.3c00119
Autor:
Akseli Hemminki, Kalevi Kairemo, Renée A. Desmond, Anu J. Airaksinen, Mikko Tenhunen, Mirkka Sarparanta, Maria Rajecki, Tanja Hakkarainen
Purpose: Oncolytic adenoviruses are promising tools for cancer therapy. Although several clinical reports have indicated both safety and promising antitumor capabilities for these viruses, there are only a few examples of complete tumor eradication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631edf772dae3a85cde1748ab870dff3
https://doi.org/10.1158/1078-0432.c.6517578.v1
https://doi.org/10.1158/1078-0432.c.6517578.v1
Autor:
Akseli Hemminki, Kalevi Kairemo, Renée A. Desmond, Anu J. Airaksinen, Mikko Tenhunen, Mirkka Sarparanta, Maria Rajecki, Tanja Hakkarainen
Supplementary Data from Targeted Radiotherapy for Prostate Cancer with an Oncolytic Adenovirus Coding for Human Sodium Iodide Symporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbf9c3d08d96500f9b076de8e0f0e51
https://doi.org/10.1158/1078-0432.22440228
https://doi.org/10.1158/1078-0432.22440228