Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Mirka, Uhlirova"'
Autor:
Swann Floc'hlay, Ramya Balaji, Dimitrije Stanković, Valerie M Christiaens, Carmen Bravo González-Blas, Seppe De Winter, Gert J Hulselmans, Maxime De Waegeneer, Xiaojiang Quan, Duygu Koldere, Mardelle Atkins, Georg Halder, Mirka Uhlirova, Anne-Kathrin Classen, Stein Aerts
Publikováno v:
eLife, Vol 12 (2023)
Wound response programs are often activated during neoplastic growth in tumors. In both wound repair and tumor growth, cells respond to acute stress and balance the activation of multiple programs, including apoptosis, proliferation, and cell migrati
Externí odkaz:
https://doaj.org/article/466fad16d6af41f0a02156a24ebcaa84
Publikováno v:
eLife, Vol 9 (2020)
Blood development in multicellular organisms relies on specific tissue microenvironments that nurture hematopoietic precursors and promote their self-renewal, proliferation, and differentiation. The mechanisms driving blood cell homing and their inte
Externí odkaz:
https://doaj.org/article/93fc270162894b86aa451f1761f16544
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 6 (2020)
Retinitis pigmentosa (RP) represents genetically heterogeneous and clinically variable disease characterized by progressive degeneration of photoreceptors resulting in a gradual loss of vision. The autosomal dominant RP type 13 (RP13) has been linked
Externí odkaz:
https://doaj.org/article/4f11d4c3f57a478d8510b3f294da03ce
Publikováno v:
Cell Reports, Vol 27, Iss 10, Pp 3019-3033.e5 (2019)
Summary: Homeostatic renewal and stress-related tissue regeneration rely on stem cell activity, which drives the replacement of damaged cells to maintain tissue integrity and function. The Jun N-terminal kinase (JNK) signaling pathway has been establ
Externí odkaz:
https://doaj.org/article/4ed65337c57e4fa18d12e5c183f766cd
Autor:
Andrea Cosolo, Janhvi Jaiswal, Gábor Csordás, Isabelle Grass, Mirka Uhlirova, Anne-Kathrin Classen
Publikováno v:
eLife, Vol 8 (2019)
The restoration of homeostasis after tissue damage relies on proper spatial-temporal control of damage-induced apoptosis and compensatory proliferation. In Drosophila imaginal discs these processes are coordinated by the stress response pathway JNK.
Externí odkaz:
https://doaj.org/article/c729baca0cf24f6fb98cdc297a44aa18
Co-transcriptional processing of nascent pre-mRNAs by the spliceosome is vital to regulating gene expression and maintaining genome integrity. Here, we show that the deficiency of functional U5 snRNPs inDrosophilaimaginal cells causes extensive trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::305c1cc63df989a1f97d885d16f86091
https://doi.org/10.1101/2023.04.06.535851
https://doi.org/10.1101/2023.04.06.535851
Autor:
Colin D Donohoe, Gábor Csordás, Andreia Correia, Marek Jindra, Corinna Klein, Bianca Habermann, Mirka Uhlirova
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007241 (2018)
Interplay between apicobasal cell polarity modules and the cytoskeleton is critical for differentiation and integrity of epithelia. However, this coordination is poorly understood at the level of gene regulation by transcription factors. Here, we est
Externí odkaz:
https://doaj.org/article/bc96d75b631940de9a73a964f449af4b
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 10, Pp 1279-1293 (2015)
Cancer initiation and maintenance of the transformed cell state depend on altered cellular signaling and aberrant activities of transcription factors (TFs) that drive pathological gene expression in response to cooperating genetic lesions. Decipherin
Externí odkaz:
https://doaj.org/article/078d8ace304948d5882a5ffe5e166db1
Autor:
Ann-Katrin Claudius, Steffen Erkelenz, Juliane Mundorf, Niels H. Gehring, Dimitrije Stanković, Volker Boehm, Mirka Uhlirova, Tina Bresser
Publikováno v:
Nucleic Acids Research
Pre-mRNA splicing catalyzed by the spliceosome represents a critical step in the regulation of gene expression contributing to transcriptome and proteome diversity. The spliceosome consists of five small nuclear ribonucleoprotein particles (snRNPs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10970a7d42a53256c2935550f320f34
https://doi.org/10.1093/nar/gkaa1274
https://doi.org/10.1093/nar/gkaa1274