Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mirjana Lilić"'
Publikováno v:
Immunogenetics. 55:740-747
MHC class I molecules are heterotrimeric complexes composed of heavy chain, beta2-microglobulin (beta2m) and short peptide. This trimeric complex is generated in the endoplasmic reticulum (ER), where a peptide loading complex (PLC) facilitates transp
Publikováno v:
The Journal of Immunology. 169:4945-4950
Mice with fibroblast-specific expression of TAP-1 were generated by expressing the TAP-1 transgene under the control of the fibroblast-specific protein (FSP) 1 promoter/enhancer on TAP-1-deficient background. MHC class I expression in primary fibrobl
Autor:
Anastasia Gkeka, Francisco Aresta-Branco, Gianna Triller, Evi P. Vlachou, Monique van Straaten, Mirjana Lilic, Paul Dominic B. Olinares, Kathryn Perez, Brian T. Chait, Renata Blatnik, Thomas Ruppert, Joseph P. Verdi, C. Erec Stebbins, F. Nina Papavasiliou
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112262- (2023)
Summary: The African trypanosome survives the immune response of its mammalian host by antigenic variation of its major surface antigen (the variant surface glycoprotein or VSG). Here we describe the antibody repertoires elicited by different VSGs. W
Externí odkaz:
https://doaj.org/article/eb43510b214a4df1a0e7c607d76c984e
Autor:
Mila Jankovic, Stanislav Vukmanovic, Kimary Kulig, Mirjana Lilić, Kristin Remus, Ilhem Messaoudi, Janko Nikolić-Žugić
Publikováno v:
European Journal of Immunology. 29:3971-3977
Cytotoxicity is a major effector function of CD8(+) T cells. Although mitogen-activated protein kinase (MAP kinase) / extracellular regulatory kinase (ERK) activity is indispensable for cytotoxic activity of most CD8(+) T cells a portion of CD8(+) T
Publikováno v:
Immunogenetics. 55(11)
MHC class I molecules are heterotrimeric complexes composed of heavy chain, beta2-microglobulin (beta2m) and short peptide. This trimeric complex is generated in the endoplasmic reticulum (ER), where a peptide loading complex (PLC) facilitates transp
Autor:
Cristina Colarossi, Fabio R. Santori, Yan Chen, Mirjana Lilić, Daniel B. Rifkin, Branka Dabovic, Stanislav Vukmanovic
Publikováno v:
Journal of cellular physiology. 196(2)
The latent TGF-β binding protein (LTBP)-3 is an extracellular matrix (ECM) protein that binds the small latent complex (SLC) of TGF-β. Disruption of the Ltbp-3 gene by homologous recombination in mice yields mutant animals that display multiple ske
Publikováno v:
The Journal of Immunology. 169:4674-4674
Allelic exclusion is inefficient at the TCRα locus, allowing a sizeable portion of T cells to carry two functional TCRs. The potential danger of dual TCR expression is a rescue of autoreactive TCRs during selection in the thymus and subsequent devel
Autor:
James Peek, Mirjana Lilic, Daniel Montiel, Aleksandr Milshteyn, Ian Woodworth, John B. Biggins, Melinda A. Ternei, Paula Y. Calle, Michael Danziger, Thulasi Warrier, Kohta Saito, Nathaniel Braffman, Allison Fay, Michael S. Glickman, Seth A. Darst, Elizabeth A. Campbell, Sean F. Brady
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Resistance to rifamycin antibiotics, which target bacterial RNA polymerases, is a growing problem. Here, the authors identify gene clusters from soil metagenomes encoding production of rifamycin analogues that are active against rifampicin-resistant
Externí odkaz:
https://doaj.org/article/9a2754d11dc34b7e92b8fd4db1a27cbf
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that rev
Externí odkaz:
https://doaj.org/article/133287ec42704d49bf169ec537d59a2a
Autor:
Hande Boyaci, James Chen, Mirjana Lilic, Margaret Palka, Rachel Anne Mooney, Robert Landick, Seth A Darst, Elizabeth A Campbell
Publikováno v:
eLife, Vol 7 (2018)
Fidaxomicin (Fdx) is an antimicrobial RNA polymerase (RNAP) inhibitor highly effective against Mycobacterium tuberculosis RNAP in vitro, but clinical use of Fdx is limited to treating Clostridium difficile intestinal infections due to poor absorption
Externí odkaz:
https://doaj.org/article/ed35d087085b40cab9518a2253b5c555