Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Mirjam de With"'
Autor:
Mirjam de With, Leni van Doorn, Demi C. Maasland, Tessa A.M. Mulder, Esther Oomen-de Hoop, Bianca Mostert, Marjolein Y.V. Homs, Samira El Bouazzaoui, Ron H.J. Mathijssen, Ron H.N. van Schaik, Sander Bins
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114232- (2023)
Aim of the study: Occurrence of hand-foot syndrome (HFS) during capecitabine treatment often results in treatment interruptions (26 %) or treatment discontinuation (17 %), and can severely decrease quality of life. In this study, we investigated whet
Externí odkaz:
https://doaj.org/article/22d712ca5f2d4b6f9d5ea8fc0cd5da1f
Autor:
Tessa A. M. Mulder, Ruben A. G. van Eerden, Mirjam de With, Laure Elens, Dennis A. Hesselink, Maja Matic, Sander Bins, Ron H. J. Mathijssen, Ron H. N. van Schaik
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Cytochrome P450 3A4 (CYP3A4) is the most important drug metabolizing enzyme in the liver, responsible for the oxidative metabolism of ∼50% of clinically prescribed drugs. Therefore, genetic variation in CYP3A4 could potentially affect the pharmacok
Externí odkaz:
https://doaj.org/article/80b85a597c65408aa28ded486cfab7e7
Autor:
Mirjam de With, Daan P. Hurkmans, Esther Oomen-de Hoop, Ayoub Lalouti, Sander Bins, Samira El Bouazzaoui, Mandy van Brakel, Reno Debets, Joachim G. J. V. Aerts, Ron H. N. van Schaik, Ron H. J. Mathijssen, Astrid A. M. van der Veldt
Publikováno v:
Cancers, Vol 13, Iss 6, p 1370 (2021)
A substantial number of melanoma patients do not benefit from therapy with anti-PD-1. Therefore, we investigated the predictive value of single nucleotide polymorphisms (SNPs) in genes related to the PD-1 axis in patients with metastatic melanoma. Fr
Externí odkaz:
https://doaj.org/article/80870d1cbe06490eb2522fc633a65fa5
Autor:
Tessa A. M. Mulder, Mirjam de With, Marzia del Re, Romano Danesi, Ron H. J. Mathijssen, Ron H. N. van Schaik
Publikováno v:
Cancers, Vol 13, Iss 4, p 771 (2021)
Tamoxifen is a major option for adjuvant endocrine treatment in estrogen receptor (ER) positive breast cancer patients. The conversion of the prodrug tamoxifen into the most active metabolite endoxifen is mainly catalyzed by the enzyme cytochrome P45
Externí odkaz:
https://doaj.org/article/86be4f072425464e853c57d34737328d
Autor:
Bram C. Agema, Stijn L.W. Koolen, Mirjam de With, Nadia van Doorn, Niels Heersche, Esther Oomen-de Hoop, Sabine Visser, Joachim G.J.V. Aerts, Sander Bins, Ron H.N. van Schaik, Ron H.J. Mathijssen
Publikováno v:
Genes, Vol 11, Iss 4, p 358 (2020)
Cisplatin is a chemotherapeutic agent widely used for multiple indications. Unfortunately, in a substantial set of patients treated with cisplatin, dose-limiting acute kidney injury (AKI) occurs. Here, we assessed the association of 3 catechol-O-meth
Externí odkaz:
https://doaj.org/article/cf1c68e17c244ecca7095093d6e0a4e2
Publikováno v:
BMJ case reports. 15(11)
Two patients with an acute left-sided colonic obstruction had a successful decompression after construction of a blowhole transverse colostomy as a bridge to surgery. However, they presented with two rather unknown stoma-related complications during
Autor:
Bruijn, Mirjam De, author
Publikováno v:
Strength beyond Structure: Social and Historical Trajectories of Agency in Africa. 6:263-284
Autor:
Melina De Dijn, Catho Jacobs, Eline Zenner, Laura Ihalainen, Minna Palander-Collin, Elizabeth Peterson, Sanne Arens, Mirjam De Baar, Jeroen Touwen, Liesbet Heyvaert
Publikováno v:
Arts and Humanities in Higher Education. 22:194-210
OECD reports a mismatch between field of study and job content for Humanities students, while at the same time signalling labour market shortages for skills that seem clearly linked with the Humanities, e.g. delivering information. In order to invest
Publikováno v:
HRI 2023-Companion of the ACM/IEEE International Conference on Human-Robot Interaction, 495-499
STARTPAGE=495;ENDPAGE=499;TITLE=HRI 2023-Companion of the ACM/IEEE International Conference on Human-Robot Interaction
STARTPAGE=495;ENDPAGE=499;TITLE=HRI 2023-Companion of the ACM/IEEE International Conference on Human-Robot Interaction
Gender and anthropomorphism play a substantial role in how social robots are perceived. In child-robot interaction, children's perception of the robot can be influenced by individual factors, such as the robot's gender. The purpose of this study is t
Autor:
Mirjam de Bruin-Hoegée, Latifa Lamriti, Jan P. Langenberg, René C. M. Olivier, Lai Fun Chau, Marcel J. van der Schans, Daan Noort, Arian C. van Asten
Publikováno v:
Analytical Methods. 15:142-153
The continuing threats of military conflicts and terrorism may involve the misuse of chemical weapons. The present study aims to use environmental samples to find evidence of the release of such agents at an incident scene. A novel approach was devel