Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mirjam Weibel"'
Publikováno v:
The Journal of Neuroscience. 28:5149-5158
In the genesis of Alzheimer's disease (AD), converging lines of evidence suggest that amyloid-β peptide (Aβ) triggers a pathogenic cascade leading to neuronal loss. It was long assumed that Aβ had to be assembled into extracellular amyloid fibrils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828d98b5bb93bf39b3e39d35dbb7d1d2
https://doi.org/10.1523/jneurosci.4878-07.2008
https://doi.org/10.1523/jneurosci.4878-07.2008
Publikováno v:
Journal of Biological Chemistry. 281:38905-38917
S100A16 protein is a new and unique member of the EF-hand Ca(2+)-binding proteins. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. In the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5096738be998bc9bcbdcf20c77b70537
https://doi.org/10.1074/jbc.m605798200
https://doi.org/10.1074/jbc.m605798200
Autor:
Peter Kleinert, Claus W. Heizmann, Mirjam Weibel, Günter Fritz, Peter M. H. Kroneck, Thorsten Ostendorp, Estelle Leclerc
Publikováno v:
Biochemical and Biophysical Research Communications. 347:4-11
RAGE is a multi-ligand receptor involved in various human diseases including diabetes, cancer or Alzheimer's disease. Engagement of RAGE by its ligands triggers activation of key cellular signalling pathways such as the MAP kinase and NF-kappaB pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8c8cb8e7d3b090d0afdd60ce26cd23
https://doi.org/10.1016/j.bbrc.2006.04.077
https://doi.org/10.1016/j.bbrc.2006.04.077
The receptor for advanced glycation endproducts (RAGE) interacts with several ligands and is involved in various human diseases. RAGE_v1 or sRAGE, a RAGE splice variant, is secreted and contributes to the removal of RAGE ligands. Because RAGE blockad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f64e8da19602081953e2f1f0116118
https://doi.org/10.5167/uzh-4577
https://doi.org/10.5167/uzh-4577
Publikováno v:
The Journal of biological chemistry. 282(43)
S100 proteins are EF-hand calcium-binding proteins with various intracellular functions including cell proliferation, differentiation, migration, and apoptosis. Some S100 proteins are also secreted and exert extracellular paracrine and autocrine func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca05b3e36923fb878c4cce20a12e10cb
https://pubmed.ncbi.nlm.nih.gov/17726019
https://pubmed.ncbi.nlm.nih.gov/17726019
Autor:
Mirjam Weibel, Beat W. Schäfer, Matthias Höchli, Stefano Ferrari, Miro Makek, Andrea Mueller, Claus W. Heizmann
Head and neck squamous cell carcinoma express high levels of the EF-hand calcium-binding protein S100A2 in contrast to other tumorigenic tissues and cell lines where the expression of this protein is reduced. Subtractive hybridization of tumorigenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4a02a96b6575f7710b1c6ab4ca0c21
https://doi.org/10.5167/uzh-34239
https://doi.org/10.5167/uzh-34239