The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophagesin vivo

Autor: Akram A. Da’dara, Donald A. Harn, Mirjam Walker, Olga Atochina

Publikováno v: Immunology. 125:111-121

The early pathogen-macrophage interactions that help drive macrophage maturation towards classically or alternatively activated are largely unknown. To examine this question we utilized the immunomodulatory glycan Lacto-N-fucopentaose III (LNFPIII),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb0793a09ba20db4a1777d2a5161124
https://doi.org/10.1111/j.1365-2567.2008.02826.x

Secondary and primary murine alveolar echinococcosis: combined albendazole/nitazoxanide chemotherapy exhibits profound anti-parasitic activity

Autor: Regula Theurillat, Eric Dricot, Renate Fink, Bruno Gottstein, Andrew Hemphill, Mirjam Walker, Wolfgang Thormann, Marianne Stettler, Jean François Rossignol, Michael Merli, Rudi Segers

Publikováno v: International Journal for Parasitology. 34:615-624

In this study, the efficacies of chemotherapy employing nitazoxanide (NTZ), albendazole (ABZ), and a NTZ/ABZ-combination against alveolar echinococcosis (AE) were investigated in an experimental murine model. Following secondary infection, meaning i.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ef4b42ee59ad18dc04a5fd17fc7190
https://doi.org/10.1016/j.ijpara.2004.01.006

In Vitro Parasiticidal Effect of Nitazoxanide against Echinococcus multilocularis Metacestodes

Autor: Bruno Gottstein, Andrew Hemphill, Mirjam Walker, Timothy G. Geary, Jean François Rossignol, Marianne Stettler, Renate Fink

Publikováno v: Antimicrobial Agents and Chemotherapy. 47:467-474

When humans serve as inadvertent intermediate hosts for Echinococcus multilocularis , disease (alveolar echinococcosis [AE]) may result from the expanding parasite metacestode in visceral organs, mostly in the liver. Benzimidazole carbamate derivativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8681eecfe0b2441229495b6d249f2c7a
https://doi.org/10.1128/aac.47.2.467-474.2003

The separate and combined effects of MHC genotype, parasite clone, and host gender on the course of malaria in mice

Autor: Mirjam Walker, Tom J. Little, Claus Wedekind

Publikováno v: Wedekind, C, Walker, M & Little, T 2006, ' The separate and combined effects of MHC genotype, parasite clone, and host gender on the course of malaria in mice ', BMC Genetics, vol. 7, no. 55, pp.-. https://doi.org/10.1186/1471-2156-7-55
BMC Genetics, vol. 7, pp. 55
BMC Genetics
BMC Genetics, Vol 7, Iss 1, p 55 (2006)

Background The link between host MHC (major histocompatibility complex) genotype and malaria is largely based on correlative data with little or no experimental control of potential confounding factors. We used an experimental mouse model to test for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aacc858c0888074feda885ad9500bc
https://hdl.handle.net/20.500.11820/ef967123-7634-4eaf-9f37-4bfc53cb0a85

The Course of Malaria in Mice: Major Histocompatibility Complex (MHC) Effects, but No General MHC Heterozygote Advantage in Single-Strain Infections

Autor: Claus Wedekind, Mirjam Walker, Tom J. Little

A general MHC-heterozygote advantage in parasite-infected organisms is often assumed, although there is little experimental evidence for this. We tested the response of MHC-congenic mice (F2 segregants) to malaria and found the course of infection to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2f09d7cd6e1710318db60b8d603471
https://europepmc.org/articles/PMC1451180/