Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Mirjam Koker"'
Autor:
Caroline Volz, Sara Breid, Carolin Selenz, Alina Zaplatina, Kristina Golfmann, Lydia Meder, Felix Dietlein, Sven Borchmann, Sampurna Chatterjee, Maike Siobal, Jakob Schöttle, Alexandra Florin, Mirjam Koker, Marieke Nill, Luka Ozretić, Niklas Uhlenbrock, Steven Smith, Reinhard Büttner, Hui Miao, Bingcheng Wang, H. Christian Reinhardt, Daniel Rauh, Michael Hallek, Amparo Acker-Palmer, Lukas C. Heukamp, Roland T. Ullrich
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp - (2020)
Summary: Anti-angiogenic treatment targeting vascular endothelial growth factor (VEGF)-VEGFR2 signaling has shown limited efficacy in lung cancer patients. Here, we demonstrate that inhibition of VEGFR2 in tumor cells, expressed in ∼20% of non-squa
Externí odkaz:
https://doaj.org/article/facb3169b7084c8eb4f67f107da06c75
Autor:
Martin Peifer, Jonathan Weiss, Martin L Sos, Mirjam Koker, Stefanie Heynck, Christian Netzer, Stefanie Fischer, Haridas Rode, Daniel Rauh, Jörg Rahnenführer, Roman K Thomas
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8919 (2010)
Despite the successful introduction of potent anti-cancer therapeutics, most of these drugs lead to only modest tumor-shrinkage or transient responses, followed by re-growth of tumors. Combining different compounds has resulted in enhanced tumor cont
Externí odkaz:
https://doaj.org/article/d43d914520a846449df82e6532342907
Autor:
Tiago Fleming Outeiro, Preeti Putcha, Julie E Tetzlaff, Robert Spoelgen, Mirjam Koker, Filipe Carvalho, Bradley T Hyman, Pamela J McLean
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1867 (2008)
Misfolding, oligomerization, and fibrillization of alpha-synuclein are thought to be central events in the onset and progression of Parkinson's disease (PD) and related disorders. Although fibrillar alpha-synuclein is a major component of Lewy bodies
Externí odkaz:
https://doaj.org/article/b569cc7153d54f5ab0860498cc320da9
Autor:
Tiago Fleming Outeiro, Preeti Putcha, Julie E. Tetzlaff, Robert Spoelgen, Mirjam Koker, Filipe Carvalho, Bradley T. Hyman, Pamela J. McLean
Publikováno v:
PLoS ONE, Vol 3, Iss 5 (2008)
Externí odkaz:
https://doaj.org/article/87500420071f489b83281ab9e8f0f4e6
Autor:
Roland T Ullrich, Thomas Zander, Bernd Neumaier, Mirjam Koker, Takeshi Shimamura, Yannic Waerzeggers, Christa L Borgman, Samir Tawadros, Hongfeng Li, Martin L Sos, Heiko Backes, Geoffrey I Shapiro, Jürgen Wolf, Andreas H Jacobs, Roman K Thomas, Alexandra Winkeler
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3908 (2008)
BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations of EGFR were found in lung adenocarcinoma that lead to exquisite dependen
Externí odkaz:
https://doaj.org/article/8f3796ed7f8842debdaa3df812da553c
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
mp3 file (6.8 MB). In the inaugural edition of the Cancer Discovery podcast, Executive Editor Mark Landis talks with Matthew Meyerson about his paper, which describes the identification of the DDR2 kinase as a therapeutic target in squamous cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e5addd2d5a8ac8b634e34fdba42185
https://doi.org/10.1158/2159-8290.22529081
https://doi.org/10.1158/2159-8290.22529081
Autor:
Roman K. Thomas, Yasushi Yatabe, Stefan A. Haas, Sascha Ansén, Sven Perner, Jürgen Wolf, Thomas Zander, Reinhard Buettner, Lukas C. Heukamp, Martin Vingron, Dirk Brehmer, Marc Parade, Souichi Ogata, Timothy Perera, Idoya Lahortiga, Vito M. Fazio, Annamaria la Torre, Lucia A. Muscarella, Jörg Sänger, Joachim H. Clement, Iver Petersen, Erich Stoelben, Johannes M. Heuckmann, Peter Nürnberg, Christian Becker, Janine Altmüller, Sylvie Lantuejoul, Christian G. Brambilla, Denis Moro-Sibilot, Hélène Nagy-Mignotte, Elisabeth Brambilla, Benjamin Solomon, Zoe Wainer, Prudence A. Russell, Gavin M. Wright, Roland T. Ullrich, Mirjam Koker, Ilona Dahmen, Wenzel Vogel, Jakob Schöttle, Florian Malchers, Juliane Daßler, Marc Bos, Martin Peifer, Sandra Ortiz-Cuaran, Frauke Leenders, Roopika Menon, Ruping Sun, Hirotaka Osada, Dennis Plenker, Lynnette Fernandez-Cuesta
XLSX file 75K, This is an excel file containing 9 sheets, one for each of the 9 supplementary tables (S1 to S9) mentioned in the main text
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f2683ba8a868adc9f8a76d6605235a
https://doi.org/10.1158/2159-8290.22530114.v1
https://doi.org/10.1158/2159-8290.22530114.v1
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
Supplementary Table 1 from Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db13f0f0711315c79b59f97a73ae407
https://doi.org/10.1158/2159-8290.22529072
https://doi.org/10.1158/2159-8290.22529072
Autor:
Roman K. Thomas, Yasushi Yatabe, Stefan A. Haas, Sascha Ansén, Sven Perner, Jürgen Wolf, Thomas Zander, Reinhard Buettner, Lukas C. Heukamp, Martin Vingron, Dirk Brehmer, Marc Parade, Souichi Ogata, Timothy Perera, Idoya Lahortiga, Vito M. Fazio, Annamaria la Torre, Lucia A. Muscarella, Jörg Sänger, Joachim H. Clement, Iver Petersen, Erich Stoelben, Johannes M. Heuckmann, Peter Nürnberg, Christian Becker, Janine Altmüller, Sylvie Lantuejoul, Christian G. Brambilla, Denis Moro-Sibilot, Hélène Nagy-Mignotte, Elisabeth Brambilla, Benjamin Solomon, Zoe Wainer, Prudence A. Russell, Gavin M. Wright, Roland T. Ullrich, Mirjam Koker, Ilona Dahmen, Wenzel Vogel, Jakob Schöttle, Florian Malchers, Juliane Daßler, Marc Bos, Martin Peifer, Sandra Ortiz-Cuaran, Frauke Leenders, Roopika Menon, Ruping Sun, Hirotaka Osada, Dennis Plenker, Lynnette Fernandez-Cuesta
PDF file 234K, This is a file containing the list of supplementary tables, the list of supplementary figures, as well as the 7 supplementary figures (S1 to S7) and their correspondent legends, mentioned in the main text
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000f05e4cc23df9c591b388d0865f7bb
https://doi.org/10.1158/2159-8290.22530117
https://doi.org/10.1158/2159-8290.22530117
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
Supplementary Figures 1-7 from Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531f85fe4c83a1a8d4a9016eb995d4c2
https://doi.org/10.1158/2159-8290.22529075.v1
https://doi.org/10.1158/2159-8290.22529075.v1