Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mirjam H Koster"'
Autor:
Christine Müller, Laura M Zidek, Sabrina Eichwald, Gertrud Kortman, Mirjam H Koster, Cornelis F Calkhoven
Publikováno v:
eLife, Vol 11 (2022)
Chronic obesity is correlated with severe metabolic and cardiovascular diseases as well as with an increased risk for developing cancers. Obesity is usually characterized by fat accumulation in enlarged – hypertrophic – adipocytes that are a sour
Externí odkaz:
https://doaj.org/article/64bcc64988804739878871afa33841a6
Autor:
Onne A H O Ronda, Bert J M van de Heijning, Alain de Bruin, Rachel E Thomas, Ingrid Martini, Martijn Koehorst, Albert Gerding, Mirjam H Koster, Vincent W Bloks, Angelika Jurdzinski, Niels L Mulder, Rick Havinga, Eline M van der Beek, Dirk-Jan Reijngoud, Folkert Kuipers, Henkjan J Verkade
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0232069 (2020)
Mouse models are frequently used to study mechanisms of human diseases. Recently, we observed a spontaneous bimodal variation in liver weight in C57BL/6JOlaHsd mice fed a semisynthetic diet. We now characterized the spontaneous variation in liver wei
Externí odkaz:
https://doaj.org/article/7a34a45721614e4783dbcd572ecf0fb3
Autor:
Martijn G. S. Rutten, Yu Lei, Joanne H. Hoogerland, Vincent W. Bloks, Hong Yang, Trijnie Bos, Kishore A. Krishnamurthy, Aycha Bleeker, Mirjam H. Koster, Rachel E. Thomas, Justina C. Wolters, Hilda van den Bos, Gilles Mithieux, Fabienne Rajas, Adil Mardinoglu, Diana C. J. Spierings, Alain de Bruin, Bart van de Sluis, Maaike H. Oosterveer
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background Glycogen storage disease type 1a (GSD Ia) is an inborn error of metabolism caused by a defect in glucose-6-phosphatase (G6PC1) activity, which induces severe hepatomegaly and increases the risk for liver cancer. Hepatic GSD Ia is
Externí odkaz:
https://doaj.org/article/176971327ab64839a0921d89e984a866
Autor:
Catriona Ling, Christian J. Versloot, Matilda E. Arvidsson Kvissberg, Guanlan Hu, Nathan Swain, José M. Horcas-Nieto, Emily Miraglia, Mehakpreet K. Thind, Amber Farooqui, Albert Gerding, Karen van Eunen, Mirjam H. Koster, Niels J. Kloosterhuis, Lijun Chi, YueYing ChenMi, Miriam Langelaar-Makkinje, Celine Bourdon, Jonathan Swann, Marieke Smit, Alain de Bruin, Sameh A. Youssef, Marjon Feenstra, Theo H. van Dijk, Kathrin Thedieck, Johan W. Jonker, Peter K. Kim, Barbara M. Bakker, Robert H.J. Bandsma
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104809- (2023)
Summary: Background: The intestine of children with severe malnutrition (SM) shows structural and functional changes that are linked to increased infection and mortality. SM dysregulates the tryptophan-kynurenine pathway, which may impact processes s
Externí odkaz:
https://doaj.org/article/030dcd61c99342418554af2a1f59e28d
Autor:
Andrea C. Postmus, Janine K. Kruit, Roos E. Eilers, Rick Havinga, Mirjam H. Koster, Yoshikazu Johmura, Makoto Nakanishi, Bart van de Sluis, Johan W. Jonker
Publikováno v:
Toxicology and Applied Pharmacology. 468
Cancer survivors who received chemotherapy, such as the anthracycline doxorubicin (DOX), have an increased risk of developing complications later in life, including the development of chronic metabolic diseases. Although the etiology of this increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8711e2b18ac3119e7e4ea289730001a
https://doi.org/10.1016/j.taap.2023.116531
https://doi.org/10.1016/j.taap.2023.116531
Autor:
Angela J. C. Tol, Kaja Hribar, Janine Kruit, Laura Bongiovanni, Marcel A. Vieira‐Lara, Mirjam H. Koster, Niels J. Kloosterhuis, Rick Havinga, Martijn Koehorst, Alain de Bruin, Barbara M. Bakker, Maaike H. Oosterveer, Eline M. van der Beek
Publikováno v:
Journal of Physiology, 601(10), 1761-1780. Wiley-Blackwell
Journal of Physiology, 601(10), 1761-1780. BLACKWELL PUBLISHING
Tol, A J C, Hribar, K, Kruit, J, Bongiovanni, L, Vieira-Lara, M A, Koster, M H, Kloosterhuis, N J, Havinga, R, Koehorst, M, de Bruin, A, Bakker, B M, Oosterveer, M H & van der Beek, E M 2023, ' Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model ', Journal of Physiology, vol. 601, no. 10, pp. 1761-1780 . https://doi.org/10.1113/JP284061
Journal of Physiology, 601(10), 1761-1780. BLACKWELL PUBLISHING
Tol, A J C, Hribar, K, Kruit, J, Bongiovanni, L, Vieira-Lara, M A, Koster, M H, Kloosterhuis, N J, Havinga, R, Koehorst, M, de Bruin, A, Bakker, B M, Oosterveer, M H & van der Beek, E M 2023, ' Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model ', Journal of Physiology, vol. 601, no. 10, pp. 1761-1780 . https://doi.org/10.1113/JP284061
Hyperglycaemia in pregnancy (HIP) is a pregnancy complication characterized by mild to moderate hyperglycaemia that negatively impacts short- and long-term health of mother and child. However, relationships between severity and timing of pregnancy hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1ee18648d2bd9e7fcfb867525e4768
https://dspace.library.uu.nl/handle/1874/429424
https://dspace.library.uu.nl/handle/1874/429424
Autor:
José M. Horcas-Nieto, Christian J. Versloot, Miriam Langelaar-Makkinje, Albert Gerding, Tjasso Blokzijl, Mirjam H. Koster, Mirjam Baanstra, Ingrid A. Martini, Robert P. Coppes, Céline Bourdon, Sven C.D. van Ijzendoorn, Peter Kim, Robert H.J. Bandsma, Barbara M. Bakker
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1869(3):166635. ELSEVIER SCIENCE BV
Hospitalized children with severe malnutrition face high mortality rates and often suffer from hepatic and intestinal dysfunction, with negative impacts on their survival. New treatments cannot be developed without understanding the underlying pathop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7048c101f100238dd1fe5d1f89b110
https://pubmed.ncbi.nlm.nih.gov/36581145
https://pubmed.ncbi.nlm.nih.gov/36581145
Autor:
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven
Publikováno v:
Hepatology
The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co-expressed with the MT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb94768e1a81ce10629a43080da15007
https://hdl.handle.net/1887/3502375
https://hdl.handle.net/1887/3502375
Autor:
Anouk M. La Rose, Anouk G. Groenen, Benedek Halmos, Venetia Bazioti, Martijn G.S. Rutten, Kishore A. Krishnamurthy, Mirjam H. Koster, Niels J. Kloosterhuis, Marieke Smit, Rick Havinga, Gilles Mithieux, Fabienne Rajas, Folkert Kuipers, Maaike H. Oosterveer, Marit Westerterp
Publikováno v:
Molecular genetics and metabolism reports, 31:100872. ELSEVIER SCIENCE BV
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Elsevier, 2022, 31, pp.100872. ⟨10.1016/j.ymgmr.2022.100872⟩
Molecular genetics and metabolism reports, 31. ELSEVIER SCIENCE BV
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Elsevier, 2022, 31, pp.100872. ⟨10.1016/j.ymgmr.2022.100872⟩
Molecular genetics and metabolism reports, 31. ELSEVIER SCIENCE BV
International audience; Glycogen storage disease type 1a (GSD Ia) is an inborn error of carbohydrate metabolism. Despite severe hyperlipidemia, GSD Ia patients show limited atherogenesis compared to age-and-gender matched controls. Employing a GSD Ia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06623b936939b70b1a20d74655821967
https://doi.org/10.1016/j.ymgmr.2022.100872
https://doi.org/10.1016/j.ymgmr.2022.100872
Autor:
Venetia Bazioti, Anouk M. La Rose, Sjors Maassen, Frans Bianchi, Rinse de Boer, Emma Guilbaud, Arthur Flohr-Svendsen, Anouk G. Groenen, Alejandro Marmolejo-Garza, Mirjam H. Koster, Niels J. Kloosterhuis, Alle T. Pranger, Miriam Langelaar-Makkinje, Alain de Bruin, Bart van de Sluis, Alison B. Kohan, Laurent Yvan-Charvet, Geert van den Bogaart, Marit Westerterp
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During aging, T-cells accumulate cholesterol, which could lead to a pro-inflammatory phenotype. However, the role of cholesterol efflux pathways mediated by ATP-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f3f0739dddbc3921360c452fcf7e068
https://doi.org/10.1101/2022.04.10.487770
https://doi.org/10.1101/2022.04.10.487770