Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mirjam E Belderbos"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33419 (2012)
Human neonates are highly susceptible to infection, which may be due in part to impaired innate immune function. Neonatal Toll-like receptor (TLR) responses are biased against the generation of pro-inflammatory/Th1-polarizing cytokines, yet the under
Externí odkaz:
https://doaj.org/article/0495c8d01767430d9ec34521a5d43bca
Autor:
Edyta E. Wojtowicz, Jayna J. Mistry, Vladimir Uzun, Charlotte Hellmich, Anita Scoones, Desmond W. Chin, Laura M. Kettyle, Francesca Grasso, Allegra M. Lord, David J. Wright, Graham J. Etherington, Petter S. Woll, Mirjam E. Belderbos, Kristian M. Bowles, Claus Nerlov, Wilfried Haerty, Leonid V. Bystrykh, Sten Eirik W. Jacobsen, Stuart A. Rushworth, Iain C. Macaulay
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-27 (2023)
Abstract Background Platelets and erythrocytes constitute over 95% of all hematopoietic stem cell output. However, the clonal dynamics of HSC contribution to these lineages remains largely unexplored. Results We use lentiviral genetic labeling of mou
Externí odkaz:
https://doaj.org/article/1e471c0563ff42f9a6e250e9ee8b4611
Autor:
Joost B. Koedijk, Thomas B. van Beek, Marijn A. Vermeulen, Lennart A. Kester, Elizabeth K. Schweighart, Stefan Nierkens, Mirjam E. Belderbos, C. Michel Zwaan, Katja M. J. Heitink-Pollé, Olaf Heidenreich
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Regression of leukemia in the absence of disease-modifying therapy remains poorly understood, although immunological mechanisms are thought to play a role. Here, we present a unique case of a 17-year-old boy with immune dysregulation and long-lasting
Externí odkaz:
https://doaj.org/article/b1ef9090fbca46babb653538dcd1bab1
Publikováno v:
Cells, Vol 10, Iss 8, p 2051 (2021)
Graft-versus-host disease (GvHD) is a major complication of allogeneic hematopoietic (stem) cell transplantation (HCT). Clinically, GvHD is associated with severe and long-lasting hematopoietic dysfunction, which may contribute to the high mortality
Externí odkaz:
https://doaj.org/article/41f86d2fe0594e88ae4ef7216a24cc5d
Autor:
Athel Cornish-Bowden, David Rasnick, Henry H. Heng, Steven Horne, Batoul Abdallah, Guo Liu, Christine J. Ye, Mathew Bloomfield, Mark D. Vincent, C. Marcelo Aldaz, Jenny Karlsson, Anders Valind, Caroline Jansson, David Gisselsson, Jennifer A. Marshall Graves, Aleksei A. Stepanenko, Svitlana V. Andreieva, Kateryna V. Korets, Dmytro O. Mykytenko, Nataliya L. Huleyuk, Vladimir P. Baklaushev, Oksana A. Kovaleva, Vladimir P. Chekhonin, Yegor S. Vassetzky, Stanislav S. Avdieiev, Bjorn Bakker, Aaron S. Taudt, Mirjam E. Belderbos, David Porubsky, Diana C. J. Spierings, Tristan V. de Jong, Nancy Halsema, Hinke G. Kazemier, Karina Hoekstra-Wakker, Allan Bradley, Eveline S. J. M. de Bont, Anke van den Berg, Victor Guryev, Peter M. Lansdorp, Maria Colomé Tatché, Floris Foijer, Thomas Liehr, Nicolaas C. Baudoin, Joshua M. Nicholson, Kimberly Soto, Isabel Quintanilla, Jordi Camps, Daniela Cimini, M. Dürrbaum, N. Donnelly, V. Passerini, C. Kruse, B. Habermann, Z. Storchová, Daniele Mandrioli, Fiorella Belpoggi, Ellen K Silbergeld, Melissa J Perry, Rolf I. Skotheim, Marthe Løvf, Bjarne Johannessen, Andreas M. Hoff, Sen Zhao, Jonas M. SveeStrømme, Anita Sveen, Ragnhild A. Lothe, R. Hehlmann, A. Voskanyan, A. Fabarius, Alfred Böcking, Stefan Biesterfeld, Leonid Berynskyy, Christof Börgermann, Rainer Engers, Josef Dietz, A. Fritz, N. Sehgal, J. Vecerova, B. Stojkovicz, H. Ding, N. Page, C. Tye, S. Bhattacharya, J. Xu, G. Stein, J. Stein, R. Berezney, Xue Gong, Sarah Grasedieck, Julian Swoboda, Frank G. Rücker, Lars Bullinger, Jonathan R. Pollack, Fani-Marlen Roumelioti, Maria Chiourea, Christina Raftopoulou, Sarantis Gagos, Peter Duesberg, Mat Bloomfield, Sunyoung Hwang, Hans Tobias Gustafsson, Ciara O’Sullivan, Aracelli Acevedo-Colina, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, Eduardo M. Torres, Martha R. Stampfer, Lukas Vrba, Mark A. LaBarge, Bernard Futscher, James C. Garbe, Yi-Hong Zhou, Andrew L. Trinh, Michelle Digman
Publikováno v:
Molecular Cytogenetics, Vol 10, Iss S2, Pp 77-94 (2017)
Externí odkaz:
https://doaj.org/article/b6866d4289674f288bf6c946e8f882e4
Autor:
Ruben van Boxtel, Mirjam E. Belderbos, Joske Ubels, Freek Manders, Mark Verheul, Rurika Oka, Damon A. Hofman, Markus J. van Roosmalen, Eline J.M. Bertrums, Arianne M. Brandsma
Supplementary Table S1-10 providing details on study cohorts and sequencing results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604bd120ff80da895a88fc9deab43276
https://doi.org/10.1158/2643-3230.22543153.v1
https://doi.org/10.1158/2643-3230.22543153.v1
Autor:
Ruben van Boxtel, Mirjam E. Belderbos, Joske Ubels, Freek Manders, Mark Verheul, Rurika Oka, Damon A. Hofman, Markus J. van Roosmalen, Eline J.M. Bertrums, Arianne M. Brandsma
Acquisition of oncogenic mutations with age is believed to be rate limiting for carcinogenesis. However, the incidence of leukemia in children is higher than in young adults. Here we compare somatic mutations across pediatric acute myeloid leukemia (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691d34e613ed0a121287422ff56513f1
https://doi.org/10.1158/2643-3230.c.6550159
https://doi.org/10.1158/2643-3230.c.6550159
Autor:
Ruben van Boxtel, Mirjam E. Belderbos, Joske Ubels, Freek Manders, Mark Verheul, Rurika Oka, Damon A. Hofman, Markus J. van Roosmalen, Eline J.M. Bertrums, Arianne M. Brandsma
Overview of supplementary data of this manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52f7bb39b4fdd69d494d7bbd74cf2cd
https://doi.org/10.1158/2643-3230.22543156.v1
https://doi.org/10.1158/2643-3230.22543156.v1
Autor:
Ruben van Boxtel, Mirjam E. Belderbos, Joske Ubels, Freek Manders, Mark Verheul, Rurika Oka, Damon A. Hofman, Markus J. van Roosmalen, Eline J.M. Bertrums, Arianne M. Brandsma
Supplementary Figures S1-S6 with figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1efcacdc11519bb33bce4d29d7f6ba
https://doi.org/10.1158/2643-3230.22543159.v1
https://doi.org/10.1158/2643-3230.22543159.v1
Autor:
Joost B. Koedijk, Inge van der Werf, Marijn A. Vermeulen, Alicia Perzolli, Marta Fiocco, Hester A. de Groot-Kruseman, Rubina Moeniralam, Stefan Nierkens, Mirjam E. Belderbos, C. Michel Zwaan, Olaf Heidenreich
Pediatric cancers are characterized by a relatively low mutational burden and therefore, children are thought to be poor candidates for T cell-engaging immunotherapies. Here, we performed a multidimensional characterization of the tumor immune microe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc67c90206be9a5cd7841f3a964695f6
https://doi.org/10.1101/2023.03.03.23286485
https://doi.org/10.1101/2023.03.03.23286485