Zobrazeno 1 - 10
of 724
pro vyhledávání: '"Mirjam Christ‐Crain"'
Autor:
Milica Wälchli-Popovic, Sophie Monnerat, Angela E. Taylor, Lorna C. Gilligan, Lina Schiffer, Wiebke Arlt, Deborah R. Vogt, Christian De Geyter, Nina Hutter, Marc Y. Donath, Gideon Sartorius, Mirjam Christ-Crain
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionChronic low-grade inflammation might contribute to hyperandrogenemia and metabolic complications in polycystic ovary syndrome (PCOS). The proinflammatory cytokine interleukin (IL)-1 stimulates androgen production from ovarian cells, where
Externí odkaz:
https://doaj.org/article/f9d69dc80b9d4028ad3e110759f5c3fa
Autor:
Salome Rudin, Lilian Kriemler, Tolga D. Dittrich, Annaelle Zietz, Juliane Schweizer, Markus Arnold, Nils Peters, Filip Barinka, Simon Jung, Marcel Arnold, Katharina Rentsch, Mirjam Christ-Crain, Mira Katan, Gian Marco De Marchis
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 4 (2024)
BACKGROUND: Lipoprotein (a) [Lp(a)] serum levels are highly genetically determined and promote atherogenesis. High Lp(a) levels are associated with increased cardiovascular morbidity. Serum Lp(a) levels have recently been associated with large artery
Externí odkaz:
https://doaj.org/article/73ea661fe01d4fb3bb7e6aa3f2db59d1
Autor:
Claudine A. Blum, Eva A. Roethlisberger, Nicole Cesana-Nigro, Bettina Winzeler, Nicolas Rodondi, Manuel R. Blum, Matthias Briel, Beat Mueller, Mirjam Christ-Crain, Philipp Schuetz
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Several trials and meta-analyses found a benefit of adjunct corticosteroids for community-acquired pneumonia with respect to short-term outcome, but there is uncertainty about longer-term health effects. Herein, we evaluated clini
Externí odkaz:
https://doaj.org/article/e7c13ba4ed6e475fae45dea938d10faf
Autor:
Hualin Lüthi, Sophia Lengsfeld, Thilo Burkard, Andrea Meienberg, Nica Jeanloz, Tanja Vukajlovic, Katja Bologna, Michelle Steinmetz, Cemile Bathelt, Clara O. Sailer, Mirjam Laager, Deborah R. Vogt, Lars G. Hemkens, Benjamin Speich, Sandrine A. Urwyler, Jill Kühne, Fabienne Baur, Linda N. Lutz, Tobias E. Erlanger, Mirjam Christ-Crain, Bettina Winzeler
Publikováno v:
EClinicalMedicine, Vol 68, Iss , Pp 102429- (2024)
Summary: Background: Smoking cessation is challenging, despite making use of established smoking cessation therapies. Preclinical studies and one clinical pilot study suggest the antidiabetic drug glucagon-like peptide-1 (GLP-1) analogue to modulate
Externí odkaz:
https://doaj.org/article/8c47a01a7b914ca09c486ee55de1736c
Autor:
Agathoklis Efthymiadis, Riccardo Pofi, Hussam Rostom, Tim James, Brian Shine, Nish Guha, Simon Cudlip, Mirjam Christ‐Crain, Aparna Pal
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Objective This study evaluates the predictive value of copeptin for syndrome of inappropriate antidiuresis (SIAD) postpituitary transsphenoidal surgery (TSS). Design Data from 133 consecutive patients undergoing TSS (November 2017–October
Externí odkaz:
https://doaj.org/article/7443af573bcc446f94d842a19a5d06cc
Autor:
Sophia Lengsfeld, Thilo Burkard, Andrea Meienberg, Nica Jeanloz, David Coynel, Deborah R. Vogt, Lars G. Hemkens, Benjamin Speich, Davide Zanchi, Tobias E. Erlanger, Mirjam Christ-Crain, Bettina Winzeler
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Cigarette smoking is the leading preventable cause of premature death. Despite dedicated programmes, quit rates remain low due to barriers such as nicotine withdrawal syndrome or post-cessation weight gain. Glucagon-like peptide-1
Externí odkaz:
https://doaj.org/article/44510571840b4e0ba0925baafd2209e3
Autor:
Mirjam Christ-Crain, Andrea Meienberg, Thilo Burkard, Bettina Winzeler, Fabienne Baur, Cihan Atila, Sophia Lengsfeld, Cemile Bathelt
Publikováno v:
BMJ Nutrition, Prevention & Health, Vol 6, Iss 2 (2023)
Background Women seem to have more difficulty quitting smoking than men. This is particularly concerning as smoking puts women at a higher risk of developing smoking-associated diseases. Greater concerns about postcessation weight gain in women have
Externí odkaz:
https://doaj.org/article/ee78d16bce184c48884f5d275ceef6ad
Autor:
Leila Probst, Sophie Monnerat, Deborah R. Vogt, Sophia Lengsfeld, Thilo Burkard, Andrea Meienberg, Cemile Bathelt, Mirjam Christ-Crain, Bettina Winzeler
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
BACKGROUND Alcohol use disorder has a detrimental impact on global health and new treatment targets are needed. Preclinical studies show attenuating effects of glucagon-like peptide-1 (GLP-1) agonists on addiction-related behaviors in rodents and non
Externí odkaz:
https://doaj.org/article/41d350321f8641f5a391807fdafd05c9
Autor:
Sofia Roth, Emilio Flint, Lea Ghataore, Vishal C. Patel, Arjuna Singanayagam, Royce P. Vincent, Evangelos Triantafyllou, Yun Ma, William Bernal, Georg Auzinger, Michael Heneghan, Charalambos Antoniades, Mirjam Christ-Crain, Mark J.W. McPhail, David R. Taylor, Julia Wendon, Christine Bernsmeier
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 1, Pp 72-82 (2023)
Background and Aims: The clinical, prognostic, and therapeutic impact of adrenal insufficiency in acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) remains controversial and exact diagnostic criteria are lacking. We sought to determ
Externí odkaz:
https://doaj.org/article/88eb0ec5b8d1477e8d7ccd3b1994e26e
Autor:
Luca Liberale, Stefano Ministrini, Markus Arnold, Yustina M. Puspitasari, Thomas Pokorny, Georgia Beer, Natalie Scherrer, Juliane Schweizer, Mirjam Christ-Crain, Fabrizio Montecucco, Giovanni G. Camici, Mira Katan Kahles
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract In a murine model of acute ischemic stroke, SIRT6 knockdown resulted in larger cerebral infarct size, worse neurological outcome, and higher mortality, indicating a possible neuro-protective role of SIRT6. In this study, we aimed at evaluati
Externí odkaz:
https://doaj.org/article/d6ced1e73e2e42338a2efb2724d7a9d2