Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Mirjam B Zeisel"'
Autor:
Giulia Manzoni, Carine Marinach, Selma Topçu, Sylvie Briquet, Morgane Grand, Matthieu Tolle, Marion Gransagne, Julien Lescar, Chiara Andolina, Jean-François Franetich, Mirjam B Zeisel, Thierry Huby, Eric Rubinstein, Georges Snounou, Dominique Mazier, François Nosten, Thomas F Baumert, Olivier Silvie
Publikováno v:
eLife, Vol 6 (2017)
Plasmodium sporozoites, the mosquito-transmitted forms of the malaria parasite, first infect the liver for an initial round of replication before the emergence of pathogenic blood stages. Sporozoites represent attractive targets for antimalarial prev
Externí odkaz:
https://doaj.org/article/b4f9109adff8452b8f21f8a38e13c330
Autor:
Fei Xiao, Isabel Fofana, Laura Heydmann, Heidi Barth, Eric Soulier, François Habersetzer, Michel Doffoël, Jens Bukh, Arvind H Patel, Mirjam B Zeisel, Thomas F Baumert
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004128 (2014)
Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes. Viral cell-cell transmission has been shown to play an important role in viral persistence
Externí odkaz:
https://doaj.org/article/3d82659e652242da9ba2435e2b6c3d43
Autor:
Isabel Fofana, Fei Xiao, Christine Thumann, Marine Turek, Laetitia Zona, Rajiv G Tawar, Fritz Grunert, John Thompson, Mirjam B Zeisel, Thomas F Baumert
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64221 (2013)
Hepatitis C virus (HCV) infection is a challenge to prevent and treat because of the rapid development of drug resistance and escape. Viral entry is required for initiation, spread, and maintenance of infection, making it an attractive target for ant
Externí odkaz:
https://doaj.org/article/29ea22798fa342abb6262078b3c059ec
Autor:
John M Murray, Rémy Moenne-Loccoz, Aurélie Velay, François Habersetzer, Michel Doffoël, Jean-Pierre Gut, Isabel Fofana, Mirjam B Zeisel, Françoise Stoll-Keller, Thomas F Baumert, Evelyne Schvoerer
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67254 (2013)
The poor response to the combined antiviral therapy of pegylated alfa-interferon and ribavarin for hepatitis C virus (HCV) infection may be linked to mutations in the viral envelope gene E1E2 (env), which can result in escape from the immune response
Externí odkaz:
https://doaj.org/article/2b29502375e949a3a5c99bda65528c54
Autor:
Julia Bitzegeio, Dorothea Bankwitz, Kathrin Hueging, Sibylle Haid, Christiane Brohm, Mirjam B Zeisel, Eva Herrmann, Marcus Iken, Michael Ott, Thomas F Baumert, Thomas Pietschmann
Publikováno v:
PLoS Pathogens, Vol 6, p e1000978 (2010)
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined. Virus cell entry involves human scavenger receptor class B type I (SR-BI), CD81, claudin-1 and o
Externí odkaz:
https://doaj.org/article/8993a7a785aa4054a305c13b2cffd220
Autor:
Natascha Roehlen, Marion Muller, Zeina Nehme, Emilie Crouchet, Frank Jühling, Fabio Del Zompo, Sara Cherradi, Francois H.T. Duong, Nuno Almeida, Antonio Saviano, Mirian Fernández-Vaquero, Tobias Riedl, Houssein El Saghire, Sarah C. Durand, Clara Ponsolles, Marine A. Oudot, Romain Martin, Nicolas Brignon, Emanuele Felli, Patrick Pessaux, Antonin Lallement, Irwin Davidson, Simonetta Bandiera, Christine Thumann, Patrice Marchand, Solange Moll, Brandon Nicolay, Nabeel Bardeesy, Yujin Hoshida, Mathias Heikenwälder, Roberto Iacone, Alberto Toso, Markus Meyer, Greg Elson, Tamas Schweighoffer, Geoffrey Teixeira, Mirjam B. Zeisel, Patrice Laquerriere, Joachim Lupberger, Catherine Schuster, Laurent Mailly, Thomas F. Baumert
Publikováno v:
Journal of Hepatology
Journal of Hepatology, 2023, 78 (2), pp.343-355. ⟨10.1016/j.jhep.2022.10.011⟩
Journal of Hepatology, 2023, 78 (2), pp.343-355. ⟨10.1016/j.jhep.2022.10.011⟩
Despite recent approvals, the response to treatment and prognosis of patients with advanced hepatocellular carcinoma (HCC) remain poor. Claudin-1 (CLDN1) is a membrane protein that is expressed at tight junctions, but it can also be exposed non-junct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea961a92db13717003dd14f794826042
Autor:
Natascha Roehlen, Antonio Saviano, Houssein El Saghire, Emilie Crouchet, Zeina Nehme, Fabio Del Zompo, Frank Jühling, Marine A. Oudot, Sarah C. Durand, François H. T. Duong, Sara Cherradi, Victor Gonzalez Motos, Nuno Almeida, Clara Ponsolles, Laura Heydmann, Tessa Ostyn, Antonin Lallement, Patrick Pessaux, Emanuele Felli, Andrea Cavalli, Jacopo Sgrignani, Christine Thumann, Olga Koutsopoulos, Bryan C. Fuchs, Yujin Hoshida, Maike Hofmann, Mogens Vyberg, Birgitte Martine Viuff, Elisabeth D. Galsgaard, Greg Elson, Alberto Toso, Markus Meyer, Roberto Iacone, Tamas Schweighoffer, Geoffrey Teixeira, Solange Moll, Claudio De Vito, Tania Roskams, Irwin Davidson, Danijela Heide, Mathias Heikenwälder, Mirjam B. Zeisel, Joachim Lupberger, Laurent Mailly, Catherine Schuster, Thomas F. Baumert
Publikováno v:
Roehlen, N, Saviano, A, El Saghire, H, Crouchet, E, Nehme, Z, Del Zompo, F, Jühling, F, Oudot, M A, Durand, S C, Duong, F H T, Cherradi, S, Gonzalez Motos, V, Almeida, N, Ponsolles, C, Heydmann, L, Ostyn, T, Lallement, A, Pessaux, P, Felli, E, Cavalli, A, Sgrignani, J, Thumann, C, Koutsopoulos, O, Fuchs, B C, Hoshida, Y, Hofmann, M, Vyberg, M, Viuff, B M, Galsgaard, E D, Elson, G, Toso, A, Meyer, M, Iacone, R, Schweighoffer, T, Teixeira, G, Moll, S, De Vito, C, Roskams, T, Davidson, I, Heide, D, Heikenwälder, M, Zeisel, M B, Lupberger, J, Mailly, L, Schuster, C & Baumert, T F 2022, ' A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity ', Science Translational Medicine, vol. 14, no. 676, eabj4221, pp. eabj4221 . https://doi.org/10.1126/scitranslmed.abj4221
Tissue fibrosis is a key driver of end-stage organ failure and cancer, overall accounting for up to 45% of deaths in developed countries. There is a large unmet medical need for antifibrotic therapies. Claudin-1 (CLDN1) is a member of the tight junct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a15761706f515b3e02c2102683616d7
https://vbn.aau.dk/da/publications/ae147006-4f6f-4e57-bf99-f23fc8da0fa9
https://vbn.aau.dk/da/publications/ae147006-4f6f-4e57-bf99-f23fc8da0fa9
Autor:
Catherine, Fauvelle, Laura, Heydmann, Mirjam B, Zeisel, Thomas F, Baumert, Françoise, Stoll-Keller, Samira, Fafi-Kremer
Publikováno v:
Virologie (Montrouge, France). 15(5)
Neutralizing antibodies represent a key component of immune control in many viral infections. For a long time, these antibodies were thought to play a marginal role in hepatitis C virus (HCV) infection, and that cellular immune responses are more cri
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 1715, p 1715 (2021)
Journal of Clinical Medicine, Vol 10, Iss 1715, p 1715 (2021)
Hepatocellular carcinoma (HCC) is the most frequent primary malignancy of the liver and a leading cause of cancer-related deaths worldwide. Although much progress has been made in HCC drug development in recent years, treatment options remain limited
Publikováno v:
Gut
Gut, 2018, Epub ahead of print. ⟨10.1136/gutjnl-2018-316906⟩
Gut, In press, Epub ahead of print. ⟨10.1136/gutjnl-2018-316906⟩
Gut, BMJ Publishing Group, In press, Epub ahead of print. ⟨10.1136/gutjnl-2018-316906⟩
Gut, 2018, Epub ahead of print. ⟨10.1136/gutjnl-2018-316906⟩
Gut, In press, Epub ahead of print. ⟨10.1136/gutjnl-2018-316906⟩
Gut, BMJ Publishing Group, In press, Epub ahead of print. ⟨10.1136/gutjnl-2018-316906⟩
Over the past two decades a growing body of evidence has demonstrated an important role of tight junction (TJ) proteins in the physiology and disease biology of gastrointestinal (GI) and liver disease. On one side, TJ proteins exert their functional