Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Mirjam B Zeisel"'
Autor:
Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero, Tobias Riedl, Xiaochen Sun, Hadassa Hirschfield, Frank Jühling, Shijia Zhu, Natascha Roehlen, Clara Ponsolles, Laura Heydmann, Antonio Saviano, Tongqi Qian, Anu Venkatesh, Joachim Lupberger, Eloi R. Verrier, Mozhdeh Sojoodi, Marine A. Oudot, François H. T. Duong, Ricard Masia, Lan Wei, Christine Thumann, Sarah C. Durand, Victor González-Motos, Danijela Heide, Jenny Hetzer, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Roberto Sanchez, Rosa S. Kim, C. Billie Bian, Karun Kiani, Tom Croonenborghs, Aravind Subramanian, Raymond T. Chung, Beate K. Straub, Detlef Schuppan, Maliki Ankavay, Laurence Cocquerel, Evelyne Schaeffer, Nicolas Goossens, Anna P. Koh, Milind Mahajan, Venugopalan D. Nair, Ganesh Gunasekaran, Myron E. Schwartz, Nabeel Bardeesy, Alex K. Shalek, Orit Rozenblatt-Rosen, Aviv Regev, Emanuele Felli, Patrick Pessaux, Kenneth K. Tanabe, Mathias Heikenwälder, Catherine Schuster, Nathalie Pochet, Mirjam B. Zeisel, Bryan C. Fuchs, Yujin Hoshida, Thomas F. Baumert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Drug and target discovery for advanced liver disease are hampered by a lack of suitable models for clinical translation. Here the authors present a human liver cell-based system modeling a clinical prognostic signature allowing to propose nizatidine
Externí odkaz:
https://doaj.org/article/454d7d31ae1e40b7812cd73b90a2e7e3
Autor:
Nassim Dali‐Youcef, Michel Vix, Federico Costantino, Houssein El‐Saghire, Benoit Lhermitte, Cosimo Callari, Jacopo D’Agostino, Silvana Perretta, Stefan Paveliu, Monica Gualtierotti, Edith Dumeny, Marine A. Oudot, Amélie Jaulin, Doulaye Dembélé, Mirjam B. Zeisel, Catherine Tomasetto, Thomas F. Baumert, Michel Doffoël
Publikováno v:
Hepatology Communications, Vol 3, Iss 9, Pp 1205-1220 (2019)
Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder due to increased accumulation of fat in the liver and in many cases to enhanced inflammation. Although the contribution of inflammation in the pathogenesis of NAFLD is well established,
Externí odkaz:
https://doaj.org/article/5c47567d5a5f4bdea27e87f48d9dd20c
Autor:
Eloi R. Verrier, Che C. Colpitts, Charlotte Bach, Laura Heydmann, Laetitia Zona, Fei Xiao, Christine Thumann, Emilie Crouchet, Raphaël Gaudin, Camille Sureau, François-Loïc Cosset, Jane A. McKeating, Patrick Pessaux, Yujin Hoshida, Catherine Schuster, Mirjam B. Zeisel, Thomas F. Baumert
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1357-1368 (2016)
Summary: Chronic hepatitis B, C, and D virus (HBV, HCV, and HDV) infections are the leading causes of liver disease and cancer worldwide. Recently, the solute carrier and sodium taurocholate co-transporter NTCP has been identified as a receptor for H
Externí odkaz:
https://doaj.org/article/76450073a1274eef974ae6d6530f7e6f
Autor:
Natascha Roehlen, Marion Muller, Zeina Nehme, Emilie Crouchet, Frank Jühling, Fabio Del Zompo, Sara Cherradi, Francois H.T. Duong, Nuno Almeida, Antonio Saviano, Mirian Fernández-Vaquero, Tobias Riedl, Houssein El Saghire, Sarah C. Durand, Clara Ponsolles, Marine A. Oudot, Romain Martin, Nicolas Brignon, Emanuele Felli, Patrick Pessaux, Antonin Lallement, Irwin Davidson, Simonetta Bandiera, Christine Thumann, Patrice Marchand, Solange Moll, Brandon Nicolay, Nabeel Bardeesy, Yujin Hoshida, Mathias Heikenwälder, Roberto Iacone, Alberto Toso, Markus Meyer, Greg Elson, Tamas Schweighoffer, Geoffrey Teixeira, Mirjam B. Zeisel, Patrice Laquerriere, Joachim Lupberger, Catherine Schuster, Laurent Mailly, Thomas F. Baumert
Publikováno v:
Journal of Hepatology
Journal of Hepatology, 2023, 78 (2), pp.343-355. ⟨10.1016/j.jhep.2022.10.011⟩
Journal of Hepatology, 2023, 78 (2), pp.343-355. ⟨10.1016/j.jhep.2022.10.011⟩
Despite recent approvals, the response to treatment and prognosis of patients with advanced hepatocellular carcinoma (HCC) remain poor. Claudin-1 (CLDN1) is a membrane protein that is expressed at tight junctions, but it can also be exposed non-junct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea961a92db13717003dd14f794826042
Autor:
Florian Wrensch, Emilie Crouchet, Gaetan Ligat, Mirjam B. Zeisel, Zhen-Yong Keck, Steven K. H. Foung, Catherine Schuster, Thomas F. Baumert
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
With more than 71 million people chronically infected, hepatitis C virus (HCV) is one of the leading causes of liver disease and hepatocellular carcinoma. While efficient antiviral therapies have entered clinical standard of care, the development of
Externí odkaz:
https://doaj.org/article/89e24b5529904263880055316701d415
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 11 (2018)
Chronic hepatitis C virus (HCV) infection is a leading cause of chronic liver diseases and hepatocellular carcinoma (HCC) worldwide. In the past few years, anti-HCV therapies have undergone a revolution with the approval of multiple direct-acting ant
Externí odkaz:
https://doaj.org/article/ef647efaf2444f6685d3ac548346da93
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 5659-5685 (2015)
Chronic hepatitis C virus (HCV) infection is a major cause of liver cirrhosis and hepatocellular carcinoma (HCC) which are leading indications of liver transplantation (LT). To date, there is no vaccine to prevent HCV infection and LT is invariably f
Externí odkaz:
https://doaj.org/article/6ad2ad0bb17946e69b9f9d50931c7081
Autor:
Natascha Roehlen, Antonio Saviano, Houssein El Saghire, Emilie Crouchet, Zeina Nehme, Fabio Del Zompo, Frank Jühling, Marine A. Oudot, Sarah C. Durand, François H. T. Duong, Sara Cherradi, Victor Gonzalez Motos, Nuno Almeida, Clara Ponsolles, Laura Heydmann, Tessa Ostyn, Antonin Lallement, Patrick Pessaux, Emanuele Felli, Andrea Cavalli, Jacopo Sgrignani, Christine Thumann, Olga Koutsopoulos, Bryan C. Fuchs, Yujin Hoshida, Maike Hofmann, Mogens Vyberg, Birgitte Martine Viuff, Elisabeth D. Galsgaard, Greg Elson, Alberto Toso, Markus Meyer, Roberto Iacone, Tamas Schweighoffer, Geoffrey Teixeira, Solange Moll, Claudio De Vito, Tania Roskams, Irwin Davidson, Danijela Heide, Mathias Heikenwälder, Mirjam B. Zeisel, Joachim Lupberger, Laurent Mailly, Catherine Schuster, Thomas F. Baumert
Publikováno v:
Roehlen, N, Saviano, A, El Saghire, H, Crouchet, E, Nehme, Z, Del Zompo, F, Jühling, F, Oudot, M A, Durand, S C, Duong, F H T, Cherradi, S, Gonzalez Motos, V, Almeida, N, Ponsolles, C, Heydmann, L, Ostyn, T, Lallement, A, Pessaux, P, Felli, E, Cavalli, A, Sgrignani, J, Thumann, C, Koutsopoulos, O, Fuchs, B C, Hoshida, Y, Hofmann, M, Vyberg, M, Viuff, B M, Galsgaard, E D, Elson, G, Toso, A, Meyer, M, Iacone, R, Schweighoffer, T, Teixeira, G, Moll, S, De Vito, C, Roskams, T, Davidson, I, Heide, D, Heikenwälder, M, Zeisel, M B, Lupberger, J, Mailly, L, Schuster, C & Baumert, T F 2022, ' A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity ', Science Translational Medicine, vol. 14, no. 676, eabj4221, pp. eabj4221 . https://doi.org/10.1126/scitranslmed.abj4221
Tissue fibrosis is a key driver of end-stage organ failure and cancer, overall accounting for up to 45% of deaths in developed countries. There is a large unmet medical need for antifibrotic therapies. Claudin-1 (CLDN1) is a member of the tight junct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a15761706f515b3e02c2102683616d7
https://vbn.aau.dk/da/publications/ae147006-4f6f-4e57-bf99-f23fc8da0fa9
https://vbn.aau.dk/da/publications/ae147006-4f6f-4e57-bf99-f23fc8da0fa9
Autor:
Giulia Manzoni, Carine Marinach, Selma Topçu, Sylvie Briquet, Morgane Grand, Matthieu Tolle, Marion Gransagne, Julien Lescar, Chiara Andolina, Jean-François Franetich, Mirjam B Zeisel, Thierry Huby, Eric Rubinstein, Georges Snounou, Dominique Mazier, François Nosten, Thomas F Baumert, Olivier Silvie
Publikováno v:
eLife, Vol 6 (2017)
Plasmodium sporozoites, the mosquito-transmitted forms of the malaria parasite, first infect the liver for an initial round of replication before the emergence of pathogenic blood stages. Sporozoites represent attractive targets for antimalarial prev
Externí odkaz:
https://doaj.org/article/b4f9109adff8452b8f21f8a38e13c330
Autor:
Catherine, Fauvelle, Laura, Heydmann, Mirjam B, Zeisel, Thomas F, Baumert, Françoise, Stoll-Keller, Samira, Fafi-Kremer
Publikováno v:
Virologie (Montrouge, France). 15(5)
Neutralizing antibodies represent a key component of immune control in many viral infections. For a long time, these antibodies were thought to play a marginal role in hepatitis C virus (HCV) infection, and that cellular immune responses are more cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::801b7d10c7a54ccea110d2bb43ef4ce3
https://pubmed.ncbi.nlm.nih.gov/36151691
https://pubmed.ncbi.nlm.nih.gov/36151691