Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Mirim Jin"'
Autor:
Byung Hoon Lee, Young Gon Na, Seong Hyup Ham, Mirim Jin, Yoon Tae Kim, Kyung-Ok Kim, Jae Ang Sim
Publikováno v:
Knee Surgery & Related Research, Vol 36, Iss 1, Pp 1-9 (2024)
Abstract Background To evaluate the diagnostic characteristics of tryptophanyl tRNA synthetase (WRS) for the diagnosis of septic arthritis of the knee joint and to determine whether it is a reliable and sensitive synovial biomarker for discriminating
Externí odkaz:
https://doaj.org/article/bf1a4dbdf18846f5b4fdf8262da1d4be
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 3, Pp 559-569 (2024)
Abstract Secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome (sHLH/MAS) is a life-threatening immune disorder triggered by rheumatic disease, infections, malignancies, or medications. Characterized by the presence of hemophago
Externí odkaz:
https://doaj.org/article/cdb065c671c74b969126a4ecd93e4b5c
Autor:
Yoon Tae Kim, Jin Won Huh, Yun Hui Choi, Hee Kyeong Yoon, Tram TT Nguyen, Eunho Chun, Geunyeol Jeong, Sunyoung Park, Sungwoo Ahn, Won-Kyu Lee, Young-Woock Noh, Kyoung Sun Lee, Hee-Sung Ahn, Cheolju Lee, Sang Min Lee, Kyung Su Kim, Gil Joon Suh, Kyeongman Jeon, Sunghoon Kim, Mirim Jin
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 1, Pp 40-63 (2023)
Abstract Despite intensive clinical and scientific efforts, the mortality rate of sepsis remains high due to the lack of precise biomarkers for patient stratification and therapeutic guidance. Secreted human tryptophanyl-tRNA synthetase 1 (WARS1), an
Externí odkaz:
https://doaj.org/article/95aa08b534b248e8b6128193ae67ae34
Autor:
Yoon Tae Kim, Jin Won Huh, Yun Hui Choi, Hee Kyeong Yoon, Tram TT Nguyen, Eunho Chun, Geunyeol Jeong, Sunyoung Park, Sungwoo Ahn, Won-Kyu Lee, Young-Woock Noh, Kyoung Sun Lee, Hee-Sung Ahn, Cheolju Lee, Sang Min Lee, Kyung Su Kim, Gil Joon Suh, Kyeongman Jeon, Sunghoon Kim, Mirim Jin
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 665-665 (2024)
Externí odkaz:
https://doaj.org/article/5be677541efd41a2b8e01e7a1f60e14e
Autor:
Tram Thuy Thuy Nguyen, Yun Hui Choi, Won-Kyu Lee, Yeounjung Ji, Eunho Chun, Yi Hyo Kim, Joo-Eun Lee, Hyun Suk Jung, Ji Hun Suh, Sunghoon Kim, Mirim Jin
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111905- (2023)
Summary: While cytoplasmic tryptophanyl-tRNA synthetase (WARS1) ligates tryptophan (Trp) to its cognate tRNAs for protein synthesis, it also plays a role as an innate immune activator in extracellular space. However, its secretion mechanism remains e
Externí odkaz:
https://doaj.org/article/f9bea3ba15b044638fbbfd530f900ae7
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 6, Pp 706-716 (2021)
Background: Irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder, is characterized by chronic abdominal pain and bowel habit changes. Although diverse complicated etiologies are involved in its pathogenesis, a dysregul
Externí odkaz:
https://doaj.org/article/9af27194fbb6409cb107eb22514bfb17
Autor:
Mirim Jin
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 1, Pp 1-10 (2019)
Protein synthesis: An unexpected link with immune regulation Targeting tryptophanyl tRNA synthetase (WRS), an evolutionarily conserved enzyme involved in protein synthesis, could be an effective strategy for modulating the immune system. In addition
Externí odkaz:
https://doaj.org/article/61a7545ee6cb48468bf5d0c17ada3ba2
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background So-ochim-tang-gamibang (SOCG) is a traditional Korean medicine frequently used for depression in the clinical field. In this study, we evaluated the potential genotoxicity of SOCG using three standard batteries of tests as part of
Externí odkaz:
https://doaj.org/article/15be05f39beb4a97b734a6eabe316c83
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1283 (2020)
Tryptophanyl-tRNA synthetase 1 (WARS1) is an endogenous ligand of mammalian Toll-like receptors (TLR) 2 and TLR4. Microarray data, using mRNA from WARS1-treated human peripheral blood mononuclear cells (PBMCs), had indicated WARS1 to mainly activate
Externí odkaz:
https://doaj.org/article/c742950f9c8249b1a0131d7c004e214a
Publikováno v:
Biomolecules & Therapeutics. 31:148-160