GOIZ ZAINDU study: a FINGER-like multidomain lifestyle intervention feasibility randomized trial to prevent dementia in Southern Europe

Autor: Mikel Tainta, Mirian Ecay-Torres, Maria de Arriba, Myriam Barandiaran, Ane Otaegui-Arrazola, Ane Iriondo, Maite Garcia-Sebastian, Ainara Estanga, Jon Saldias, Montserrat Clerigue, Alazne Gabilondo, Naia Ros, Justo Mugica, Aitziber Barandiaran, Francesca Mangialasche, Miia Kivipelto, Arantzazu Arrospide, Javier Mar, Pablo Martinez-Lage, on behalf of the GOIZ ZAINDU study group

Publikováno v: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)

Abstract Background GOIZ ZAINDU (“caring early” in Basque) is a pilot study to adapt the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) methodology to the Basque population and evaluate the feasibilit

Externí odkaz: https://doaj.org/article/fd23187f3d7a4d8f9dddeaa3f310873b

Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data

Autor: Isabelle Bos, Stephanie J. B. Vos, Willemijn J. Jansen, Rik Vandenberghe, Silvy Gabel, Ainara Estanga, Mirian Ecay-Torres, Jori Tomassen, Anouk den Braber, Alberto Lleó, Isabel Sala, Anders Wallin, Petronella Kettunen, José L. Molinuevo, Lorena Rami, Gaël Chetelat, Vincent de la Sayette, Magda Tsolaki, Yvonne Freund-Levi, Peter Johannsen, The Alzheimer's Disease Neuroimaging Initiative, Gerald P. Novak, Inez Ramakers, Frans R. Verhey, Pieter Jelle Visser

Publikováno v: Frontiers in Aging Neuroscience, Vol 10 (2018)

We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. We included

Externí odkaz: https://doaj.org/article/7d99b5ef6ae14298a061444872adece3

Accelerated long‐term forgetting in individuals with subjective cognitive decline and amyloid‐β positivity

Autor: Juan Fortea, María León, Pablo Martinez-Lage, José Luis Molinuevo, Natalia Valech, Lorena Rami, Raquel Sánchez-Valle, Matti Laine, Adrià Tort-Merino, Ainara Estanga, Antoni Rodríguez-Fornells, Jaume Olives, Mirian Ecay-Torres

Publikováno v: International Journal of Geriatric Psychiatry. 36:1037-1049

OBJECTIVES We studied a sample of cognitively unimpaired individuals, with and without subjective cognitive decline (SCD), in order to investigate accelerated long-term forgetting (ALF) and to explore the relationships between objective and subjectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31510a83651e7576824132498de4299
https://doi.org/10.1002/gps.5539

Cerebrospinal Fluid 7-Ketocholesterol Level is Associated with Amyloid-β42 and White Matter Microstructure in Cognitively Healthy Adults

Autor: Pablo Martinez-Lage, Javier Mar, Maria de Arriba, Henrik Zetterberg, Myriam Barandiaran, Maite Garcia-Sebastian, Mirian Ecay-Torres, Jon Saldias, Irundika H.K. Dias, Alazne Gabilondo, Jorge Villanua, Félix M. Goñi, Ane Iriondo, Arantzazu Arrospide, Ainara Estanga, Kaj Blennow, Andrea Izagirre, Beatriz Abad-García, Sara Aurtenetxe, Mikel Tainta, Montserrat Clerigue

Publikováno v: Journal of Alzheimer's Disease. 76:643-656

Background: Abnormal cholesterol metabolism changes the neuronal membrane and may promote amyloidogenesis. Oxysterols in cerebrospinal fluid (CSF) are related to Alzheimer's disease (AD) biomarkers in mild cognitive impairment and dementia. Cholester

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81285ddfa31f348cbd303ad63bdda2ad
https://doi.org/10.3233/jad-200105

On the Analysis of Speech and Disfluencies for Automatic Detection of Mild Cognitive Impairment

Autor: U. Martinez-de-Lizarduy, Elsa Fernández, Mirian Ecay-Torres, J. Garcia-Melero, Marcos Faundez-Zanuy, Blanca Beitia, Pilar Sanz, Karmele López-de-Ipiña, Pilar M. Calvo

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco

Alzheimer's disease is characterized by a progressive and irreversible cognitive deterioration. In a previous stage, the so-called Mild Cognitive Impairment or cognitive loss appears. Nevertheless, this previous stage does not seem sufficiently sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23c9c7938a6135ece6baea431dce3e9
http://hdl.handle.net/10810/50209