Výsledky vyhledávání - "Miriam Yaniz"

In Contrast to Platelet Microparticles, Red Cell Microparticles Are Anti-Inflammatory, Judging By Effect on CD11b Expression on Neutrophils

Autor: Wenche Jy, Henry Y Ahn, Robert Forestal McCauley, Martha Q. Gonzalez, Lawrence L. Horstman, Miriam Yaniz

Publikováno v: Blood. 134:3591-3591

BACKGROUND: It has been shown that platelet microparticles (PMP) exert pro-inflammatory activity. It has also been suggested that red cell MP (RMP) are similarly pro-inflammatory, but the evidence is less clear. This issue has clinical significance f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c61072b8bdc0d6989fbcaa3f7ab96df
https://doi.org/10.1182/blood-2019-128939

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Microparticle Profiles in Patients with TTP Vs. ITP

Autor: Martha Q. Gonzalez, Wenche Jy, Yeon S. Ahn, Yonette Paul, Robert Forestal McCauley, Lawrence L. Horstman, Miriam Yaniz, Robert A. Ali

Publikováno v: Blood. 132:3749-3749

BACKGROUND: Immune Thrombocytopenic Purpura (ITP) is an autoimmune disorder in which the production of antiplatelet antibodies stimulates increased clearance of platelets by macrophages of the mononuclear phagocytic system, resulting in thrombocytope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf19622fbe2d603a611f42fcb397c1e5
https://doi.org/10.1182/blood-2018-99-112963

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Cell Derived Microparticles (MP) in Different Phases of Thrombotic Thrombocytopenic Purpura (TTP) and Effect of Exchange Plasmapheresis (EPP) on Their Profiles

Autor: Wenche Jy, Lawrence L. Horstman, Miriam Yaniz, Yeon S. Ahn, Martha Q. Gonzalez, Robert A. Ali, Yonette Paul, Robert Forestal McCauley

Publikováno v: Blood. 132:3736-3736

BACKGROUND: Cell derived MPs are small membrane vesicles released during cell activation or apoptosis. They express an inside-out membrane, which exposes the negatively charged phospholipid layer outside, allowing clotting factors to be anchored and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c90545c6f86305732931f76472b9b26
https://doi.org/10.1182/blood-2018-99-115651

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Factor VII/VIIa: a new antigen in the anti-phospholipid antibody syndrome

Autor: Joaquin J. Jimenez, Carlos J. Bidot, Wenche Jy, Lawrence L. Horstman, Miriam Yaniz, Yeon S. Ahn, Huang Huisheng

Publikováno v: British Journal of Haematology. 120:618-626

We investigated antibodies to factor VII/VIIa (FVII/VIIa) and five other common target antigens in 33 patients with a history of anti-phospholipid syndrome (APS) and 50 healthy controls using an enzyme-linked immunosorbent assay (ELISA) technique. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db9be2c9dd35c40416419a5dd11e2430
https://doi.org/10.1046/j.1365-2141.2003.04161.x

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Functional Heterogeneity of Red Cell-Derived Microparticles from Different Sources: Calcium Ionophore Vs. Storage Vs. Extrusion

Autor: Sunjoo Cho, Carlos J. Bidot, Yeon S. Ahn, Wenche Jy, Lawrence L. Horstman, Miriam Yaniz

Publikováno v: Blood. 128:3770-3770

BACKGROUND. Cell derived microparticles (MP), are small vesicle ( METHODS. For RMP-Stor, samples were taken at intervals up to 42 days of PC stored at 4oC, then centrifuged to recover the RMP released. For RMP-CaI, supernatants of fresh RBC exposed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85982f7ae4d962da19e6705cb69f79ab
https://doi.org/10.1182/blood.v128.22.3770.3770

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Antiphospholipid antibodies in immune thrombocytopenic purpura tend to emerge in exacerbation and decline in remission

Autor: Wenche Jy, Yeon S. Ahn, Joaquin J. Jimenez, Carlos J. Bidot, Lawrence L. Horstman, Miriam Yaniz, Gabriela Lander, Eugene R. Ahn

Publikováno v: British journal of haematology. 128(3)

Although the presence of antiphospholipid antibodies (APLA) in immune thrombocytopenic purpura (ITP) has been reported, their clinical significance is not clear. The present study investigated APLA profiles in relation to the clinical stages of ITP.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b1ae78d8a07adf53ff13c6b45c3cc4
https://pubmed.ncbi.nlm.nih.gov/15667539

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Increased Prevalence of Anti-CD36 and Elevated Endothelial Microparticles in Patients with Recurrent Thrombosis

Autor: Wenche Jy, Carlos Bidot, Larry Horstman, Miriam Yaniz, Vincenzo Fontana, Carlos J. Bidot, Camile Ortega, Loreta Bidot, Yeon-Soong Ahn, Cynthia Petit

Publikováno v: Blood. 110:1632-1632

BACKGROUND: CD36 is a widely distributed transmembrane glycoprotein, called GpIV on platelets, involved in various physiologic processes. It has been implicated in thrombogenic pathologies such as diabetes, atherosclerosis and anti-phospholipid syndr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::061539d5237713fb17d60c5d24af57fc
https://doi.org/10.1182/blood.v110.11.1632.1632

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Antibodies Against Platelet Glycoprotein Target Antigens in Antiphospholipid Syndrome (APS)

Autor: Carlos Bidot, Martha Gonzalez, Yeon S. Ahn, Vincenzo Fontana, Wenche Jy, Lawrence L. Horstman, Miriam Yaniz, Carlos J. Bidot

Publikováno v: Blood. 108:3973-3973

Introduction: Antiphospholipid syndrome (APS) is characterized clinically by thrombotic events and the presence of antiphospholipid antibodies (aPLA) and/or lupus anticoagulant (LA). It is frequently associated with thrombocytopenia and anti-platelet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcf26a5c082a26cbb0438ddd58d7ad4b
https://doi.org/10.1182/blood.v108.11.3973.3973

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Multiple Species of Endothelial Microparticles (EMP) Released from Different Membrane Protein Clustering Domains Exhibit Distinctive Phenotypes and Activities

Autor: Lucia M. Mauro, Martha Gonzalez, Carlos J. Bidot, Joaquin J. Jimenez, Lawrence L. Horstman, Wenche Jy, Miriam Yaniz, Yeon-Soong Ahn

Publikováno v: Blood. 108:1802-1802

INTRODUCTION: We have previously shown that EMP comprise multiple species of vesicles released from endothelial cells (EC) upon stimulation. However, the mechanism underlying EMP release is not clear, nor is their functional role. We postulated that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a33b165cc478d7847532a04eba23d13
https://doi.org/10.1182/blood.v108.11.1802.1802

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Increased Procoagulant Cell-Derived Microparticles (MP) in Splenectomized Patients with ITP: New Prediisposing Factors for Thrombosis

Autor: Joaquin J. Jimenez, Carlos J. Bidot, Miriam Yaniz, Yeon S. Ahn, Pamela Dudkiewicz, Wenche Jy, Vincenzo Fontana

Publikováno v: Blood. 106:2637-2637

INTRODUCTION: Splenectomy has been widely employed in the treatment of immune thrombocytopenic purpura (ITP) and various other disorders. Increased life threatening infection is well recognized but the long-term safety of splenectomy has not yet been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c121bfdc0953d8064f6e88a983b91c75
https://doi.org/10.1182/blood.v106.11.2637.2637

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