Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Miriam Wissam Saab"'
Autor:
Renata Mangione, Cesarina Giallongo, Andrea Duminuco, Enrico La Spina, Lucia Longhitano, Sebastiano Giallongo, Daniele Tibullo, Giuseppe Lazzarino, Miriam Wissam Saab, Arianna Sbriglione, Giuseppe A. Palumbo, Andrea Graziani, Amer M. Alanazi, Valentina Di Pietro, Barbara Tavazzi, Angela Maria Amorini, Giacomo Lazzarino
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 490 (2024)
To date, little is known concerning the circulating levels of biochemically relevant metabolites (antioxidants, oxidative/nitrosative stress biomarkers, purines, and pyrimidines) in patients with primary myelofibrosis (PMF), a rare form of myeloproli
Externí odkaz:
https://doaj.org/article/c4fff10865004c64a8c0c75fd6bf624e
Autor:
Anna Privitera, Vincenzo Cardaci, Dhanushka Weerasekara, Miriam Wissam Saab, Lidia Diolosà, Annamaria Fidilio, Renaud Blaise Jolivet, Giuseppe Lazzarino, Angela Maria Amorini, Massimo Camarda, Susan Marie Lunte, Filippo Caraci, Giuseppe Caruso
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Carnosine (β-alanyl-L-histidine) is a naturally occurring endogenous peptide widely distributed in excitable tissues such as the brain. This dipeptide possesses well-demonstrated antioxidant, anti-inflammatory, and anti-aggregation properties, and i
Externí odkaz:
https://doaj.org/article/788c4e4dc10b4032950643d211bbf34b
Autor:
Giacomo Lazzarino, Renata Mangione, Miriam Wissam Saab, Barbara Tavazzi, Alessandra Pittalà, Stefano Signoretti, Valentina Di Pietro, Giuseppe Lazzarino, Angela Maria Amorini
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 985 (2023)
To date, there is no information on the effect of TBI on the changes in brain CoQ levels and possible variations in its redox state. In this study, we induced graded TBIs (mild TBI, mTBI and severe TBI, sTBI) in male rats, using the weight-drop close
Externí odkaz:
https://doaj.org/article/17bbf2aa8d1a457fa6ac1d273d7b181b
Autor:
Giuseppe Caruso, Anna Privitera, Miriam Wissam Saab, Nicolò Musso, Salvatore Maugeri, Annamaria Fidilio, Anna Provvidenza Privitera, Alessandra Pittalà, Renaud Blaise Jolivet, Luca Lanzanò, Giuseppe Lazzarino, Filippo Caraci, Angela Maria Amorini
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 474 (2023)
The activity of microglia is fundamental for the regulation of numerous physiological processes including brain development, synaptic plasticity, and neurogenesis, and its deviation from homeostasis can lead to pathological conditions, including nume
Externí odkaz:
https://doaj.org/article/578389f3abce4bf287c34aae31ee9a46
Autor:
Giacomo Lazzarino, Angela M. Amorini, Renata Mangione, Miriam Wissam Saab, Enrico Di Stasio, Michelino Di Rosa, Barbara Tavazzi, Giuseppe Lazzarino, Graziano Onder, Angelo Carfì
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1208 (2022)
Down Syndrome (DS) is a neurodevelopmental disorder that is characterized by an accelerated aging process, frequently associated with the development of Alzheimer’s disease (AD). Previous studies evidenced that DS patients have various metabolic an
Externí odkaz:
https://doaj.org/article/ce877677eba94bb8ac555832920ec049
Publikováno v:
Life, Vol 11, Iss 11, p 1256 (2021)
Brain-derived neurotrophic factor (BDNF) represents one of the most widely studied neurotrophins because of the many mechanisms in which it is involved. Among these, a growing body of evidence indicates BDNF as a pleiotropic signaling molecule and un
Externí odkaz:
https://doaj.org/article/635e84d7a21343ab9035c596acfaf436
Autor:
Angela Maria Amorini, Ilaria Listorti, Gabriele Bilotta, Romina Pallisco, Miriam Wissam Saab, Renata Mangione, Benedetta Manca, Giacomo Lazzarino, Barbara Tavazzi, Giuseppe Lazzarino, Pasquale Bilotta
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 220 (2021)
Under physiological conditions, reactive oxygen species (ROS) play pivotal roles in various processes of human spermatozoa. Indeed, semen requires the intervention of ROS to accomplish different stages of its maturation. However, ROS overproduction i
Externí odkaz:
https://doaj.org/article/86e3c118661e4eec8a50b2aa2e752e75
Autor:
Daniele Tibullo, Cesarina Giallongo, Alessandra Romano, Nunzio Vicario, Alessandro Barbato, Fabrizio Puglisi, Rosalba Parenti, Angela Maria Amorini, Miriam Wissam Saab, Barbara Tavazzi, Renata Mangione, Maria Violetta Brundo, Giacomo Lazzarino, Giuseppe Alberto Palumbo, Giovanni Li Volti, Francesco Di Raimondo, Giuseppe Lazzarino
Publikováno v:
Biomolecules, Vol 10, Iss 5, p 696 (2020)
The proteasome inhibitor bortezomib (BTZ) has emerged as an effective drug for the treatment of multiple myeloma even though many patients relapse from BTZ therapy. The present study investigated the metabolic pathways underlying the acquisition of b
Externí odkaz:
https://doaj.org/article/afb6104d5ad14a24a39567924c6114ba
Autor:
Andrea Magrì, Salvatore Antonio Maria Cubisino, Giuseppe Battiato, Cristiana Lucia Rita Lipari, Stefano Conti Nibali, Miriam Wissam Saab, Alessandra Pittalà, Angela Maria Amorini, Vito De Pinto, Angela Messina
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3687
Volume 24
Issue 4
Pages: 3687
Voltage-Dependent Anion-selective Channel isoform 1 (VDAC1) is the most abundant isoform of the outer mitochondrial membrane (OMM) porins and the principal gate for ions and metabolites to and from the organelle. VDAC1 is also involved in a number of
Autor:
Romina Pallisco, Giacomo Lazzarino, Gabriele Bilotta, Francesca Marroni, Renata Mangione, Miriam Wissam Saab, Maria Violetta Brundo, Alessandra Pittalà, Giuseppe Caruso, Elena Capoccia, Giuseppe Lazzarino, Barbara Tavazzi, Pasquale Bilotta, Angela Maria Amorini
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 890
Notwithstanding the great improvement of ART, the overall rate of successful pregnancies from implanted human embryos is definitely low. The current routine embryo quality assessment is performed only through morphological criteria, which has poor pr