Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Miriam Tschirschmann"'
Autor:
Georg Matziolis, Jens Tuischer, Moritz Hoeft, Desiree Zander, Mark S. Thompson, Niels Dankert, Miriam Tschirschmann, Juliane D. Glaeser, Timo Gaber, Grit Kasper, Georg N. Duda
In fracture and bone defect healing, MSCs largely drive tissue regeneration. MSCs have been shown to promote angiogenesis both in vivo and in vitro. Angiogenesis is a prerequisite to large tissue reconstitution. The present study investigated how mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a751cc2a00a1d60000811b745a4b8d06
https://ora.ox.ac.uk/objects/uuid:a9ca34b8-b56e-4fef-8c65-0c4533b560d6
https://ora.ox.ac.uk/objects/uuid:a9ca34b8-b56e-4fef-8c65-0c4533b560d6
Autor:
Frank Buttgereit, Gerd-Rüdiger Burmester, Grit Sandig, René Dziurla, Monique Fangradt, Karolina Tykwinska, Kerem Erekul, Paula Kolar, Martin Lautenbach, Miriam Tschirschmann, Timo Gaber, Thomas Häupl, M. Hahne
Publikováno v:
The Journal of Rheumatology. 36:2655-2669
Objective.Inflamed tissues are usually characterized by low oxygen levels. We investigated whether pathophysiological hypoxia (pO2< 1%) as found in the rheumatoid synovium modulates the transcriptome of human CD4+ T cells.Methods.We analyzed the exte
Insights into Mesenchymal Stem Cell Aging: Involvement of Antioxidant Defense and Actin Cytoskeleton
Autor:
Grit Kasper, Albena Draycheva, Georg N. Duda, Lei Mao, Miriam Tschirschmann, Joachim Klose, Jirko Kühnisch, Sven Geissler, Jessica Trippens, Carsten Perka, Katharina Kaspar
Publikováno v:
Stem Cells. 27:1288-1297
Progenitor cells such as mesenchymal stem cells (MSCs) have elicited great hopes for therapeutic augmentation of physiological regeneration processes, e.g., for bone fracture healing. However, regeneration potential decreases with age, which raises q
Autor:
René Dziurla, Robert Tripmacher, Gerd-Rüdiger Burmester, Timo Gaber, Thomas Häupl, Andreas Radbruch, Andreas Grützkau, Kerem Erekul, Frank Buttgereit, Alexander Scheffold, Miriam Tschirschmann
Publikováno v:
European Journal of Immunology. 38:1631-1642
We investigated the energy-adaptive potential of human CD4(+) T cells under conditions of impaired oxidative phosphorylation (OXPHOS) and/or low glucose (inhibiting glycolysis). These cells often encounter these conditions when executing their functi
Publikováno v:
Artificial Organs. 30:775-784
A promising strategy for the regeneration of degenerated cartilage tissue structure in osteoarthritic joints is the use of mesenchymal precursor cells. These cells can be triggered to undergo differentiation into functional active chondrocytes result
Autor:
Karen Stout-Weider, Niels Dankert, Grit Kasper, Detlev Mennerich, Miriam Tschirschmann, Matthias Reule, Kerstin Lehmann, Evelin Schröck, Roland Lauster, Georg N. Duda
Publikováno v:
BMC Cancer, Vol 7, Iss 1, p 12 (2007)
BMC Cancer
BMC Cancer
Background Stromelysin-3 (ST-3) is over-expressed in the majority of human carcinomas including breast carcinoma. Due to its known effect in promoting tumour formation, but its impeding effect on metastasis, a dual role of ST-3 in tumour progression,
Publikováno v:
Chemie Ingenieur Technik. 79:1382-1383
Autor:
Miriam Tschirschmann, Radoslav Chekerov, Jalid Sehouli, Christina Fotopoulou, Toralf Reimer, Lukas Angleitner-Boubenizek, Elena Ioana Braicu, Horst Lindhofer, Klaus Pietzner, Alexander Reinthaller, Daniel Reimer
Publikováno v:
Journal of Clinical Oncology. 30:5080-5080
5080 Background: Advanced ovarian cancer is still connected to high mortality rates due to intraperitoneal tumor cells that survive radical cytoreductive surgery as well as adjuvant chemotherapy. These persistent tumor cells need to be targeted in or